MangoRx vs Willow: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher

Reviewed & updated August 14, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

54 providers verified independently·Independent research·How we rank →

Short answer: MangoRx and Willow tie at 7.5/10 on our rubric, so the decision comes down to price and format rather than overall quality. Full reasoning, pricing and the cases where the other one wins are below.

Visit MangoRx - our pick of these two →or find your match

MangoRx and Willow are tied at 7.5/10. Choose MangoRx for needle-phobic users who want oral-only glp-1 tablets from a publicly traded company. Choose Willow for users who want comprehensive clinical support with flexibility between injectable and oral compounded semaglutide routes.

A side-by-side look at MangoRx and Willow to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

MangoRx

#22 of 54

7.5/10

Multi-service telehealth platform offering compounded GLP-1 alongside other health services.

Visit MangoRx

Willow

#20 of 54

7.5/10

Personalized GLP-1 weight loss with ongoing clinical support. Compounded semaglutide and tirzepatide only, Willow explicitly does not prescribe brand-name Wegovy or Zepbound. Added oral compounded semaglutide tablets as a non-injectable option.

Visit Willow

Feature	MangoRx	Willow
Why each one	Oral dissolving tablets exclusively (zero injections) from a publicly traded company (NASDAQ: MGRX) with SEC-level financial transparency.	One of the few compounded-only platforms offering both injectable and daily oral semaglutide tablets, useful for users who want a non-injectable option without leaving the GLP-1 compounded category.
Our Score	7.5/10	7.5/10
Headline Price	from $299/mo	from $299/mo
Medication Type	Compounded	Compounded
Insurance Accepted	No	No
Best For	Needle-phobic users who want oral-only GLP-1 tablets from a publicly traded company	Users who want comprehensive clinical support with flexibility between injectable and oral compounded semaglutide routes
Watch out for	Oral semaglutide at $299/mo runs 2-3x injectable alternatives ($99-149/mo). The premium only makes sense if needles are a hard no for you.	Compounded-only, no brand-name Wegovy or Zepbound through the platform
Ranking	#22	#20
Get started	Visit MangoRx	Visit Willow

Pros & Cons Compared

MangoRx

Pros

+Oral dissolving tablets exclusively, zero injections for any GLP-1 option
+Publicly traded on NASDAQ (MGRX), SEC-required financial transparency that private competitors can't match
+Semaglutide tablet includes Vitamin B6 to help reduce nausea during treatment
+Free 100% online consultation with no video call required

Cons

−Oral semaglutide at $299/mo runs 2-3x injectable alternatives ($99-149/mo). The premium only makes sense if needles are a hard no for you.
−Early-stage public company with limited revenue; the same SEC filings that provide transparency also show the financial uncertainty reflected in the stock.
−Oral tablets are the only format, with no injectable option if you want higher bioavailability. If you may switch to injections later, pick a platform that carries both.

Willow

Pros

+Includes monthly provider check-ins and dose adjustments at no extra cost
+Offers both injectable AND oral compounded semaglutide, one of few platforms with a daily oral tablet option
+$299/mo all-in for compounded semaglutide with monthly provider support
+90%+ patient retention rate after 3 months per their published outcomes data

Cons

−Compounded-only, no brand-name Wegovy or Zepbound through the platform
−Tirzepatide pricing reaches $499-$524 at higher doses, starting dose is $399/mo
−Cash-pay only, no insurance billing, though they provide superbills for FSA/HSA
−Founded in 2024, less track record than Ro or Hims, though growth has been fast

Our Verdict

MangoRx and Willow are closely matched with identical scores of 7.5/10.

Cheapest complete recurring price in our index

Trimi Health

$175/mo month-to-month, from $99 on a plan · 4.2/10 · Compounded

Both MangoRx and Willow start above the cheapest complete recurring program we track. Across all 54 providers in our index, the lowest price with affirmative medication, consultation, and shipping inclusion is Trimi Health at $175/mo. It scores 4.2/10 and is not the highest-scored provider in our full rankings, so this is a cost floor rather than a recommendation. Worth knowing before you decide.