MangoRx vs Willow: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher

Reviewed & updated September 3, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

34 providers verified independently·Independent research·How we rank →

Short answer: MangoRx and Willow tie at 7.5/10 on our rubric, so the decision comes down to price and format rather than overall quality. Full reasoning, pricing and the cases where the other one wins are below.

Visit MangoRx - our pick of these two →or find your match

MangoRx and Willow are tied at 7.5/10. Published pricing is not a like-for-like monthly comparison: MangoRx is from $299/mo; Willow is $299 first month, then $499/mo. Choose MangoRx for needle-phobic users who want oral-only glp-1 tablets from a publicly traded company. Choose Willow for users who want comprehensive clinical support with a needle-free daily tablet option on both semaglutide and tirzepatide.

A side-by-side look at MangoRx and Willow to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

MangoRx

#12 of 34

7.5/10

Men's telehealth platform built around erectile function, testosterone and hair treatments, with one compounded GLP-1 tablet, Slim, as its entire weight loss line.

Visit MangoRx

Willow

#10 of 34

7.5/10

Personalized GLP-1 weight loss with ongoing clinical support. The catalogue is compounded semaglutide, compounded tirzepatide and a compounded combination tablet carrying both, with no brand-name Wegovy or Zepbound page anywhere on the site. Daily oral dissolving tablets exist for BOTH molecules alongside the injectables, level with the corresponding injection at the starting doses. Willow serves 36 states, not all 50.

Visit Willow

Feature	MangoRx	Willow
Why each one	Oral dissolving tablets exclusively (zero injections) from a publicly traded company (NASDAQ: MGRX) with SEC-level financial transparency.	The only compounded platform on our index with daily dissolving tablets for BOTH semaglutide and tirzepatide at the injection's starting price, plus a combination tablet carrying the two molecules together, the widest needle-free menu in the compounded category.
Our Score	7.5/10	7.5/10
Headline Price	from $299/mo	$299 first month, then $499/mo
Medication Type	Compounded	Compounded
Insurance Accepted	No	No
Best For	Needle-phobic users who want oral-only GLP-1 tablets from a publicly traded company	Users who want comprehensive clinical support with a needle-free daily tablet option on both semaglutide and tirzepatide
Watch out for	Oral semaglutide at $299/mo runs 2-3x injectable alternatives ($99-149/mo). The premium only makes sense if needles are a hard no for you.	Compounded-only, no brand-name Wegovy or Zepbound through the platform
Ranking	#12	#10
Get started	Visit MangoRx	Visit Willow

Pros & Cons Compared

MangoRx

Pros

+Oral dissolving tablets exclusively, zero injections for any GLP-1 option
+Publicly traded on NASDAQ (MGRX), SEC-required financial transparency that private competitors can't match
+Semaglutide tablet includes Vitamin B6 to help reduce nausea during treatment
+Intake is 100% online with no insurance needed, and the provider visit costs nothing when it ends in a prescription

Cons

−Oral semaglutide at $299/mo runs 2-3x injectable alternatives ($99-149/mo). The premium only makes sense if needles are a hard no for you.
−Early-stage public company with limited revenue; the same SEC filings that provide transparency also show the financial uncertainty reflected in the stock.
−Oral tablets are the only format, with no injectable option if you want higher bioavailability. If you may switch to injections later, pick a platform that carries both.

Willow

Pros

+Includes monthly provider check-ins and dose adjustments at no extra cost
+Daily oral tablets for BOTH semaglutide and tirzepatide, one of the only platforms with a needle-free route on both molecules
+$299/mo covers compounded semaglutide at the starting doses, injectable or tablet, with monthly provider support and no separate consultation fee
+A US licensed doctor reviews and confirms the prescription the same day, and two-day shipping is free, both stated on the product pages (verified 2026-09-03)

Cons

−Compounded-only, no brand-name Wegovy or Zepbound through the platform
−Both headline prices are floors. Tirzepatide starts at $399/mo against $299 for semaglutide, and on the help center pricing article maintenance tirzepatide injections run $499/mo from 8.5 mg, $524/mo at 13.5 mg and $549/mo at 17 mg (checked 2026-09-03)
−Cash-pay only. Willow does not bill insurance. You pay with an HSA or FSA card at checkout, or pay out of pocket and submit receipts to your insurer yourself, with reimbursement depending on your plan and deductible (checked 2026-09-03)
−The program auto-renews, and a cancellation has to reach the care team at least two business days before the next processing date to stop a charge. A full refund only applies if you cancel before the prescription goes to the pharmacy, and the informed consent page says orders cannot be cancelled, returned or refunded once shipped (checked 2026-09-03)

Our Verdict

MangoRx and Willow are closely matched with identical scores of 7.5/10. Published pricing is not a like-for-like monthly comparison: MangoRx is from $299/mo; Willow is $299 first month, then $499/mo.

Cheapest complete recurring price in our index

Eden Health GLP-1

$99/mo month-to-month, from $34 on a plan · 6.9/10 · Both

Both MangoRx and Willow start above the cheapest complete recurring program we track. Across all 34 providers in our index, the lowest price with affirmative medication, consultation, and shipping inclusion is Eden Health GLP-1 at $99/mo, price checked August 28, 2026. It scores 6.9/10 and is not the highest-scored provider in our full rankings, so this is a cost floor rather than a recommendation. Worth knowing before you decide.