Sesame Care vs Wellorithm: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice
36 providers verified independently·Independent researchHow we rank →

Short answer: Sesame Care scores higher on our rubric, 7.9/10 against 7.4/10. Full reasoning, pricing and the cases where the other one wins are below.

Sesame Care beats Wellorithm overall, scoring 7.9/10 vs 7.4/10. Published pricing is not a like-for-like monthly comparison: Sesame Care is published $99/mo; total not verified; Wellorithm is from $147/mo. Choose Sesame Care for users who want cheap fda-approved brand-name glp-1 access ($149-349/mo wegovy and zepbound via success by sesame), or insured patients who just need a prescriber. Choose Wellorithm for cash-pay patients who want compounded semaglutide or tirzepatide in a rare oral dissolving tablet format, backed by a 10% weight-loss money-back guarantee and 24/7 support.

A side-by-side look at Sesame Care and Wellorithm to help you decide. We compare them on:

  • Starting price and billing period
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for
Higher Rated

Sesame Care

#3 of 36
7.9/10

Telehealth marketplace with two routes to a GLP-1 prescription: one-off video visits that start at $34 on the homepage, and the Success by Sesame subscription, which the weight loss program page prices at $59/mo on a 12-month commitment or $99 billed every 28 days with no commitment. It coordinates FDA-approved brand-name medication only, including Foundayo (orforglipron), the Wegovy pen and pill, and Zepbound. Medication is billed separately.

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Wellorithm

#13 of 36
7.4/10

Telehealth platform offering compounded semaglutide and tirzepatide in BOTH injectable and oral dissolving tablet formats, alongside brand-name Wegovy, Ozempic, Zepbound and Mounjaro on their own product pages, plus NAD+ and Sermorelin on the same pricing grid (verified 2026-09-03). A 10% weight-loss guarantee refunds up to four months of program fees if the patient does not lose at least 10% of baseline weight after 16 weeks of medication adherence (terms apply). 28-day recurring billing, non-refundable per-cycle.

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FeatureSesame CareWellorithm
Why each oneThe broadest FDA-approved brand-name GLP-1 menu among low-cost telehealth options, Wegovy pen and pill, Zepbound, Ozempic, Mounjaro, Rybelsus, and Foundayo, coordinated through the Success by Sesame membership at $59/mo on a 12-month commitment plus medication.
The combination of compounded GLP-1 in BOTH injectable and oral dissolving tablet formats AND a 10% weight-loss money-back guarantee, a format breadth and outcome-tied refund policy that few compounded-only platforms offer in combination, paired with the trade-off that no founder or legal entity is named on the site.
Our Score7.9/107.4/10
Headline Pricepublished $99/mo; total not verifiedfrom $147/mo
Medication TypeBrandBoth
Insurance AcceptedYesNo
Best ForUsers who want cheap FDA-approved brand-name GLP-1 access ($149-349/mo Wegovy and Zepbound via Success by Sesame), or insured patients who just need a prescriber
Cash-pay patients who want compounded semaglutide or tirzepatide in a rare oral dissolving tablet format, backed by a 10% weight-loss money-back guarantee and 24/7 support
Watch out forSesame runs three separate routes under one brand: the Success by Sesame weight loss subscription, EverydayRx for diabetes, and one-off visits from $34. Check which one you are signing up for before you pay.
Founding year, corporate ownership and the legal entity behind the program are not published on wellorithm.com; the Terms describe it only as 'a Miami-based company' that connects patients with unnamed 'Professional Entities' (verified 2026-09-03). The program page and every medication page do name three partner physicians, and the contact page gives a Miami street address and phone, so the gap is corporate rather than clinical
Ranking#3#13
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Pros & Cons Compared

Sesame Care

Pros

  • +Success by Sesame is $59/mo on the 12-month commitment and includes provider visits, unlimited messaging and provider choice; lab work is covered only at Quest Diagnostics and not in AZ, HI, ND, NJ, NY, OK, RI, SD or WY, where lab fees are extra; medication is separate
  • +Brand-name cash pricing is competitive, Wegovy pen $199 intro / $349 ongoing, Zepbound vial $299, Wegovy pill $149
  • +Foundayo (Lilly's FDA-approved oral GLP-1) available as of April 2026 at $149/mo
  • +The pay-per-visit route is still there, with visits starting at $34, for users who just need a prescriber

Cons

  • Sesame runs three separate routes under one brand: the Success by Sesame weight loss subscription, EverydayRx for diabetes, and one-off visits from $34. Check which one you are signing up for before you pay.
  • The $59/mo Success by Sesame rate applies only on a 12-month commitment. The 3-month plan works out near $79/mo and the 6-month near $69/mo from the savings the FAQ publishes, and the no-commitment plan is $99 billed every 28 days, which is 13 charges a year.
  • There is no compounded option. Sesame states that compounded semaglutide is not currently available through it, so every route here is brand-name and the medication is billed on top of the program fee.
  • A marketplace rather than a concierge, expect less hand-holding than dedicated subscription platforms

Wellorithm

Pros

  • +Compounded GLP-1 available in BOTH injectable AND oral dissolving tablet formats, semaglutide and tirzepatide each in two formats, broader format menu than most compounded-only platforms
  • +10% weight-loss money-back guarantee: patients who don't lose at least 10% of baseline weight after 16 weeks of medication adherence may be eligible for refund of up to four months of program fees (verified weight documentation required)
  • +Competitive entry pricing, $147/mo compounded semaglutide and $249/mo compounded tirzepatide put Wellorithm near the cheaper end of the compounded market
  • +Short online eligibility quiz, virtual consultation, 24/7 support availability claimed
  • +23,000+ reviews and 4.9-star rating reported (volume is unusually high for this market segment, verify on independent third-party sources before relying on it)
  • +Spring promotion advertised at $147 with free shipping included

Cons

  • Founding year, corporate ownership and the legal entity behind the program are not published on wellorithm.com; the Terms describe it only as 'a Miami-based company' that connects patients with unnamed 'Professional Entities' (verified 2026-09-03). The program page and every medication page do name three partner physicians, and the contact page gives a Miami street address and phone, so the gap is corporate rather than clinical
  • 49 states only, service is unavailable in Louisiana and outside the United States
  • Billing runs on a 28-day recurring cycle and payments are non-refundable once processed, with no proration for partial months; cancel before your next cycle processes to avoid paying for an unused month
  • The weight-loss guarantee has strict eligibility terms: verified weight documentation (doctor attestation or video evidence), prior medication history disclosure, consistent dosing adherence, and refund processed within 30 days of approval, with only fees actually paid refundable and baseline payments non-refundable; document your starting weight from day one if you plan to rely on it
  • Brand-name prices carry conditions the headline figures do not show: the Ozempic and Zepbound pages advertise $1,119 a month at the top and $1,199 a month in the pricing card, and all four brand pages footnote that the figure applies to a 500mg three-month plan paid upfront or through a buy now, pay later program (verified 2026-09-03). Budget for the prepaid plan, not the monthly number

Our Verdict

Sesame Care edges out Wellorithm with a score of 7.9/10 vs 7.4/10. Published pricing is not a like-for-like monthly comparison: Sesame Care is published $99/mo; total not verified; Wellorithm is from $147/mo. Sesame Care accepts insurance, which can significantly reduce your out-of-pocket costs. Wellorithm offers both brand-name and compounded medications, giving you more flexibility.

Try Wellorithm

Headline price: from $147/mo

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