Independent provider comparison
Updated September 21, 2026
PeterMD vs SynergyRx: Which GLP-1 provider is better?
A side-by-side look at total cost, medication format, care, commitment and the situations where each option makes more sense.
The decision
Which should you choose, PeterMD or SynergyRx?
Short answer: SynergyRx scores higher on our published rubric, 7.6/10 against 7.3/10. Published pricing is not a like-for-like monthly comparison: PeterMD is from $149/mo; SynergyRx is from $199/mo.
Consider PeterMD if
Budget-conscious users looking for the lowest monthly GLP-1 cost.
Consider SynergyRx if
Needle-phobic users who want oral dissolving tablets for semaglutide or tirzepatide, with 24/7 support included.
Scores follow our published methodology. Partnership status does not change the score or the factual comparison.
Cost
First charge, renewal and commitment
Treatment
Medication, form and approval status
Care
Clinical review and ongoing support
Terms
Cancellation and material cautions
PeterMD
#14 of 36Best for budget-conscious users looking for the lowest monthly glp-1 cost.
Visit PeterMD
SynergyRx
#9 of 36Best for needle-phobic users who want oral dissolving tablets for semaglutide or tirzepatide, with 24/7 support included.
View SynergyRx termsSide by side
PeterMD vs SynergyRx at a glance
Compare the price unit as well as the number. A medication-only price, prepaid monthly equivalent and complete recurring program are not the same thing.
| Feature | PeterMD | SynergyRx |
|---|---|---|
| Why each one | Two compounded programs at two prices: GLP1 plus B12 from $149/mo, and tirzepatide plus B12 at $209/mo for any dose, with the page stating the price does not rise as your dose increases. | Offers oral dissolving tablets for semaglutide and tirzepatide alongside injectable options. Discuss the specific formulation and its supporting evidence with your prescriber rather than assuming the same results across routes. |
| Our Score | 7.3/10 | 7.6/10 |
| Headline Price | from $149/mo | from $199/mo |
| Medication Type | Compounded | Both |
| Insurance Accepted | No | No |
| Best For | Budget-conscious users looking for the lowest monthly GLP-1 cost | Needle-phobic users who want oral dissolving tablets for semaglutide or tirzepatide, with 24/7 support included |
| Watch out for | The excluded states differ by page: the GLP1 plus B12 program lists AL, ID, AK and HI, the tirzepatide page lists only AL and ID, and the intake form asks about Alabama, Arkansas, Idaho and Hawaii. Confirm your own state during signup before planning around PeterMD. | The Casper, WY address in its terms is a suite mailbox rather than a clinic, and the brand has no Trustpilot profile, so there is little independent feedback to weigh against its own testimonials. |
| Ranking | #14 | #9 |
| Get started | Visit PeterMD | View SynergyRx terms |
Trade-offs
Strengths and cautions compared
PeterMD
Pros
- +The tirzepatide plus B12 program is one price for any dose, $209/mo, and the page says it does not go up as you titrate
- +PeterMD advertises more than 400,000 patients served and a 4.9 out of 5 rating from over 20,000 reviews
- +Semaglutide + B12 formulation helps reduce nausea, the most common GLP-1 side effect
1 more documented strengths
- +Video consultations with physicians included, real face-to-face medical oversight
Cons
- −The excluded states differ by page: the GLP1 plus B12 program lists AL, ID, AK and HI, the tirzepatide page lists only AL and ID, and the intake form asks about Alabama, Arkansas, Idaho and Hawaii. Confirm your own state during signup before planning around PeterMD.
- −Not BBB accredited, and some documented complaints cite delayed medication fulfillment. Order refills ahead of your last dose rather than at the last minute.
- −PeterMD began as a testosterone replacement therapy platform; GLP-1 is an expansion, not the original core. The included video consultations give you a direct read on the clinical team.
SynergyRx
Pros
- +Oral dissolving tablets for BOTH semaglutide AND tirzepatide, one of the few platforms with needle-free tirzepatide
- +Free expedited shipping included with all orders
- +24/7 support with unlimited messaging, no per-visit fees for follow-up questions or dose adjustments
1 more documented strengths
- +Both compounded and brand-name options available (Ozempic, Wegovy, Mounjaro)
Cons
- −The Casper, WY address in its terms is a suite mailbox rather than a clinic, and the brand has no Trustpilot profile, so there is little independent feedback to weigh against its own testimonials.
- −Brand-name pricing ($499-947/mo) is very high compared to direct manufacturer programs like LillyDirect. Use SynergyRx for its compounded oral tablets; source brand-name directly if that's what you need.
- −Founding date and ownership are not shown on the site's contact, about, terms or FAQ pages (rendered check 2026-09-03); the terms disclose only a Delaware corporation. The terms also name Usable Health, PC as the medical group while the FAQ names Lion MD.
Our Verdict
SynergyRx edges out PeterMD with a score of 7.6/10 vs 7.3/10. Published pricing is not a like-for-like monthly comparison: PeterMD is from $149/mo; SynergyRx is from $199/mo. SynergyRx offers both brand-name and compounded medications, giving you more flexibility.
Keep narrowing the decision
What should you compare next?
Use the unresolved part of this choice, not a generic related article. These guides own the broader medication, coverage or complete-cost question.
- Cost decisionCompare complete recurring program costsSee which prices include medication, clinical care and shipping, and which headline amounts require another fee or commitment.Continue
- Treatment decisionCompare semaglutide providers and pricesMove from this head-to-head to the broader semaglutide market without confusing compounded products with FDA-approved brands.Continue
- Treatment decisionCompare tirzepatide providers and pricesReview provider options, price units and treatment context across the wider tirzepatide market.Continue
Cheapest complete recurring price in our index
Eden Health GLP-1
$99/mo month-to-month, from $34 on a plan · 6.9/10 · Both
Both PeterMD and SynergyRx start above the cheapest complete recurring program we track. Across all 36 providers in our index, the lowest price with affirmative medication, consultation, and shipping inclusion is Eden Health GLP-1 at $99/mo, price checked August 28, 2026. It scores 6.9/10 and is not the highest-scored provider in our full rankings, so this is a cost floor rather than a recommendation. Worth knowing before you decide.
Reviews and pricing sources
Related comparisons
More head-to-head comparisons involving PeterMD and SynergyRx.
Not comparing, just asking? Quick answers to the most-asked GLP-1 questions →
- Compare PeterMD and bmiMDfrom $159/mo
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- Compare PeterMD and TMatesfrom $158/mo
- Compare SynergyRx and Shedfrom $159/mo
- Compare SynergyRx and bmiMDfrom $159/mo
- Compare SynergyRx and Hers$188 first month, then $298/mo
Not sure which one is right for you?
Answer a few quick questions and we'll match you to the best GLP-1 provider for your needs. Or keep exploring below.
Still working out whether either one is above board? We check that separately: is PeterMD legit, with the verification evidence behind each answer.
Our pick of these two: SynergyRx · 7.6/10