PeterMD vs SynergyRx: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher

Reviewed & updated August 14, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

54 providers verified independently·Independent research·How we rank →

Short answer: SynergyRx scores higher on our rubric, 7.6/10 against 7.3/10. Full reasoning, pricing and the cases where the other one wins are below.

Visit PeterMD - from $165/mo →or find your match

SynergyRx beats PeterMD overall, scoring 7.6/10 vs 7.3/10. Published pricing is not a like-for-like monthly comparison: PeterMD is from $165/mo; SynergyRx is from $199/mo. Choose PeterMD for budget-conscious users looking for the lowest monthly glp-1 cost. Choose SynergyRx for needle-phobic users who want oral dissolving tablets for semaglutide or tirzepatide, with 24/7 support included.

A side-by-side look at PeterMD and SynergyRx to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

PeterMD

#28 of 54

7.3/10

One of the most affordable compounded GLP-1 options on the market, ideal for budget-conscious patients.

Visit PeterMD

Higher Rated

SynergyRx

#18 of 54

7.6/10

Bundled GLP-1 program with predictable pricing and round-the-clock support access for peace of mind.

Visit SynergyRx

Feature	PeterMD	SynergyRx
Why each one	Flat $165/mo pricing at all doses with semaglutide + B12 formulation (B12 helps reduce nausea), backed by 100,000+ patients and 14,000+ Trustpilot reviews.	Oral dissolving tablets for BOTH semaglutide AND tirzepatide, serving needle-phobic patients who want injectable-level results without injections.
Our Score	7.3/10	7.6/10
Headline Price	from $165/mo	from $199/mo
Medication Type	Compounded	Both
Insurance Accepted	No	No
Best For	Budget-conscious users looking for the lowest monthly GLP-1 cost	Needle-phobic users who want oral dissolving tablets for semaglutide or tirzepatide, with 24/7 support included
Watch out for	Available in 42 states, not all 50 (8 states are excluded). Check your state during signup before planning around PeterMD.	Registered at a Casper, WY address with limited independent reviews. Verify pharmacy partners and provider credentials before enrolling.
Ranking	#28	#18
Get started	Visit PeterMD	Visit SynergyRx

Pros & Cons Compared

PeterMD

Pros

+Flat $165/mo at all dose levels, price doesn't increase as you titrate up to maintenance doses
+100,000+ patient base with 4.9/5 Trustpilot rating from 14,000+ reviews, strong social proof
+Semaglutide + B12 formulation helps reduce nausea, the most common GLP-1 side effect
+Video consultations with physicians included, real face-to-face medical oversight

Cons

−Available in 42 states, not all 50 (8 states are excluded). Check your state during signup before planning around PeterMD.
−Not BBB accredited, and some documented complaints cite delayed medication fulfillment. Order refills ahead of your last dose rather than at the last minute.
−PeterMD began as a testosterone replacement therapy platform; GLP-1 is an expansion, not the original core. The included video consultations give you a direct read on the clinical team.

SynergyRx

Pros

+Oral dissolving tablets for BOTH semaglutide AND tirzepatide, one of the few platforms with needle-free tirzepatide
+Free expedited shipping included with all orders
+24/7 support with unlimited messaging, no per-visit fees for follow-up questions or dose adjustments
+Both compounded and brand-name options available (Ozempic, Wegovy, Mounjaro)

Cons

−Registered at a Casper, WY address with limited independent reviews. Verify pharmacy partners and provider credentials before enrolling.
−Brand-name pricing ($499-947/mo) is very high compared to direct manufacturer programs like LillyDirect. Use SynergyRx for its compounded oral tablets; source brand-name directly if that's what you need.
−Company history, founding date, and ownership structure are not publicly disclosed. Ask support for pharmacy and prescriber details upfront.

Our Verdict

SynergyRx edges out PeterMD with a score of 7.6/10 vs 7.3/10. Published pricing is not a like-for-like monthly comparison: PeterMD is from $165/mo; SynergyRx is from $199/mo. SynergyRx offers both brand-name and compounded medications, giving you more flexibility.