PeterMD vs SynergyRx: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher

Reviewed & updated September 3, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

54 providers verified independently·Independent research·How we rank →

Short answer: SynergyRx scores higher on our rubric, 7.6/10 against 7.3/10. Full reasoning, pricing and the cases where the other one wins are below.

Visit SynergyRx - our pick of these two →or find your match

SynergyRx beats PeterMD overall, scoring 7.6/10 vs 7.3/10. Published pricing is not a like-for-like monthly comparison: PeterMD is from $149/mo; SynergyRx is from $199/mo. Choose PeterMD for budget-conscious users looking for the lowest monthly glp-1 cost. Choose SynergyRx for needle-phobic users who want oral dissolving tablets for semaglutide or tirzepatide, with 24/7 support included.

A side-by-side look at PeterMD and SynergyRx to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

PeterMD

#25 of 54

7.3/10

One of the most affordable compounded GLP-1 options on the market, ideal for budget-conscious patients.

Visit PeterMD

Higher Rated

SynergyRx

#15 of 54

7.6/10

Bundled GLP-1 program covering the consult, medication and shipping in one monthly price, with round-the-clock support and needle-free tablet options.

Visit SynergyRx

Feature	PeterMD	SynergyRx
Why each one	Two compounded programs at two prices: GLP1 plus B12 from $149/mo, and tirzepatide plus B12 at $209/mo for any dose, with the page stating the price does not rise as your dose increases.	Oral dissolving tablets for BOTH semaglutide AND tirzepatide, serving needle-phobic patients who want injectable-level results without injections.
Our Score	7.3/10	7.6/10
Headline Price	from $149/mo	from $199/mo
Medication Type	Compounded	Both
Insurance Accepted	No	No
Best For	Budget-conscious users looking for the lowest monthly GLP-1 cost	Needle-phobic users who want oral dissolving tablets for semaglutide or tirzepatide, with 24/7 support included
Watch out for	The excluded states differ by page: the GLP1 plus B12 program lists AL, ID, AK and HI, the tirzepatide page lists only AL and ID, and the intake form asks about Alabama, Arkansas, Idaho and Hawaii. Confirm your own state during signup before planning around PeterMD.	The Casper, WY address in its terms is a suite mailbox rather than a clinic, and the brand has no Trustpilot profile, so there is little independent feedback to weigh against its own testimonials.
Ranking	#25	#15
Get started	Visit PeterMD	Visit SynergyRx

Pros & Cons Compared

PeterMD

Pros

+The tirzepatide plus B12 program is one price for any dose, $209/mo, and the page says it does not go up as you titrate
+PeterMD advertises more than 400,000 patients served and a 4.9 out of 5 rating from over 20,000 reviews
+Semaglutide + B12 formulation helps reduce nausea, the most common GLP-1 side effect
+Video consultations with physicians included, real face-to-face medical oversight

Cons

−The excluded states differ by page: the GLP1 plus B12 program lists AL, ID, AK and HI, the tirzepatide page lists only AL and ID, and the intake form asks about Alabama, Arkansas, Idaho and Hawaii. Confirm your own state during signup before planning around PeterMD.
−Not BBB accredited, and some documented complaints cite delayed medication fulfillment. Order refills ahead of your last dose rather than at the last minute.
−PeterMD began as a testosterone replacement therapy platform; GLP-1 is an expansion, not the original core. The included video consultations give you a direct read on the clinical team.

SynergyRx

Pros

+Oral dissolving tablets for BOTH semaglutide AND tirzepatide, one of the few platforms with needle-free tirzepatide
+Free expedited shipping included with all orders
+24/7 support with unlimited messaging, no per-visit fees for follow-up questions or dose adjustments
+Both compounded and brand-name options available (Ozempic, Wegovy, Mounjaro)

Cons

−The Casper, WY address in its terms is a suite mailbox rather than a clinic, and the brand has no Trustpilot profile, so there is little independent feedback to weigh against its own testimonials.
−Brand-name pricing ($499-947/mo) is very high compared to direct manufacturer programs like LillyDirect. Use SynergyRx for its compounded oral tablets; source brand-name directly if that's what you need.
−Founding date and ownership are not shown on the site's contact, about, terms or FAQ pages (rendered check 2026-09-03); the terms disclose only a Delaware corporation. The terms also name Usable Health, PC as the medical group while the FAQ names Lion MD.

Our Verdict

SynergyRx edges out PeterMD with a score of 7.6/10 vs 7.3/10. Published pricing is not a like-for-like monthly comparison: PeterMD is from $149/mo; SynergyRx is from $199/mo. SynergyRx offers both brand-name and compounded medications, giving you more flexibility.

Cheapest complete recurring price in our index

Eden Health GLP-1

$99/mo month-to-month, from $34 on a plan · 6.9/10 · Both

Both PeterMD and SynergyRx start above the cheapest complete recurring program we track. Across all 54 providers in our index, the lowest price with affirmative medication, consultation, and shipping inclusion is Eden Health GLP-1 at $99/mo, price checked August 28, 2026. It scores 6.9/10 and is not the highest-scored provider in our full rankings, so this is a cost floor rather than a recommendation. Worth knowing before you decide.