Comparison · updated October 16, 2026

MEDGm vs SynergyRx: Costs, care and treatment fit

MEDGm and SynergyRx differ in what you pay, which medicines they list and their insurance terms. Compounded medicines are not FDA-approved.

These two prices are different kinds of bill, so read the line under each price before you compare them.

Compare plans and terms

MEDGm pays us a commission when you join through our links. SynergyRx does not. That never changes a score, an order or a fact on this page. How we make money

Our MEDGm referral excludes Louisiana; Nebraska patients must be 19 or older. The provider must confirm your eligibility and medication availability. A prescription is required and is issued only if a licensed clinician finds treatment appropriate.

Which should you choose, MEDGm or SynergyRx?

Short answer: MEDGm and SynergyRx differ in what you pay, which medicines they list and their insurance terms, so the plans below decide it.

MEDGm is best for

Shoppers comparing compounded starting prices who want named pharmacy partners and are willing to confirm their exact medication and renewal cost before paying.

SynergyRx is best for

Needle-phobic users who want oral dissolving tablets for semaglutide or tirzepatide, with 24/7 support included.

The available assessments do not establish a score winner, so choose by the medicine, total cost and care you need.

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

MEDGm vs SynergyRx side by side

MEDGm and SynergyRx compared fact by fact
MEDGmSynergyRx
Price$169/mo equivalent$2,028 upfront for 12 months; applicable taxes may add to the billfrom $199/mo
MedicineBothBrand-name and compounded
Needle-free optionBothYes, a pill or other oral form
InsuranceCash-pay programNo insurance listed
ConsultationAdvertised as included in the compounded plansIncluded
ShippingIncludedFree expedited
Where it shipsOur MEDGm referral excludes Louisiana and patients under 19 in NebraskaAvailability depends on the patient's state, the service and clinician eligibility under the terms reviewed October 8, 2026; no all-state GLP-1 service list was verified
Our score7/10 Good6.2/10 Fair
Assessment limitsChecked Sep 11, 2026.Checked Oct 16, 2026; few independent reviews yet.

What MEDGm and SynergyRx plans cost

MEDGm

Publishes compounded starting prices, names its clinical group and pharmacy partners, and advertises included labs.

All 15 MEDGm plans
How MEDGm bills

Compounded semaglutide injection is $169/mo equivalent with $2,028 prepaid for 12 months. Its monthly plan is $179 for the first month with WELCOME120OFF, then $299. Tirzepatide injection and tablets have separate prices: compounded semaglutide tablets are $239/mo equivalent with $2,868 prepaid for 12 months. Brand-name membership and medication charges are separate; applicable taxes may add to the total.

We checked MEDGm's prices on October 9, 2026.

SynergyRx

Offers oral dissolving tablets for semaglutide and tirzepatide alongside injectable options. Discuss the specific formulation and its supporting evidence with your prescriber rather than assuming the same results across routes.

  • Compounded Semaglutide (injection)$199Injectable format, listed as starting at $199 on the products page
  • Compounded Semaglutide (oral dissolving tablet)$299Needle-free tablet, listed as starting at $299 on the products page
  • Compounded Tirzepatide (injection)$349Injectable format, listed as starting at $349 on the products page
All 6 SynergyRx plans
  • Compounded Tirzepatide (oral dissolving tablet)$399Needle-free tablet, listed as starting at $399 on the products page
  • Brand-Name Ozempic$499FDA-approved Ozempic with clinical support
  • Brand-Name Wegovy/Mounjaro$947FDA-approved brand-name with full clinical support
How SynergyRx bills

The $199 is the lowest compounded semaglutide injection price on its products page; the oral dissolving tablet is $299. A $100 welcome credit is advertised as applied at checkout with no code needed

We checked SynergyRx's prices on September 3, 2026.

What to watch for with MEDGm and SynergyRx

MEDGm

  • Brand-name cards show membership fees only: $99 for Zepbound or Wegovy and $171 for Ozempic, with medication charged separately
  • The $169 injection headline requires $2,028 prepaid for a year of semaglutide; monthly plans cost more and welcome discounts end after month one
MEDGm's strengths, cautions and terms

Strengths

  • Publishes compounded plan prices before intake, with consultation, labs, medication, support and delivery advertised as included
  • Names OpenLoop Health and four pharmacy partners: RedRock Pharmacy, Health Warehouse, Precision Medicine and Triad Rx
  • Advertises included labs; the specific tests and requirements need confirmation with the provider
  • Displays a linked LegitScript seal and supplied certification documentation
  • Publishes a full current-term refund if the clinician disqualifies you before the first medication shipment

More to watch for

  • The tablet's $239 monthly equivalent requires $2,868 prepaid for 12 months; the monthly welcome discount does not continue at renewal
  • No individual medical director or prescribing clinician is named on the pages checked
  • Cancel at least 72 hours before renewal. Voluntary cancellation does not refund the paid term; dispensed medication is non-refundable
Medicines listed
  • Semaglutide (compounded weekly injection; not FDA-approved)
  • Tirzepatide (compounded weekly injection; not FDA-approved)
  • Semaglutide (compounded dissolvable tablet; not FDA-approved)
  • Zepbound injection (advertised; availability subject to change)
  • Wegovy pill or pen (advertised; availability subject to change)
  • Ozempic injection (advertised; FDA-approved for type 2 diabetes)
Insurance
Cash-pay program. HSA/FSA payments are advertised, but reimbursement depends on your benefit plan.
Consultation
Advertised as included in the compounded plans
Shipping
Included
States
Our MEDGm referral excludes Louisiana and patients under 19 in Nebraska. The provider's broader US service statement remains subject to medication availability and state-specific consultation requirements. Confirm your eligibility before paying; referral restrictions checked October 8, 2026
Cancellation
Give at least 72 hours' notice before renewal. No refund for voluntary cancellation of a paid term. Medical disqualification can qualify for a full or partial refund; dispensed medication is non-refundable.

SynergyRx

  • The terms publish a Casper, WY address. The October 8, 2026 source check did not confirm a Trustpilot profile on its exact domain; that does not establish that no profile or reviews exist.
  • Historical brand-name prices were $499-947/mo. Compare the same medication, dose, eligibility and complete charge with the relevant manufacturer's program; a compounded tablet is not an FDA-approved brand equivalent.
SynergyRx's strengths, cautions and terms

Strengths

  • Oral dissolving tablets for BOTH semaglutide AND tirzepatide, one of the few platforms with needle-free tirzepatide
  • Free expedited shipping included with all orders
  • 24/7 support with unlimited messaging, no per-visit fees for follow-up questions or dose adjustments
  • Both compounded and brand-name options available (Ozempic, Wegovy, Mounjaro)

More to watch for

  • Founding date and ownership are not shown on the site's contact, about, terms or FAQ pages (rendered check 2026-09-03); the terms disclose only a Delaware corporation. The terms also name Usable Health, PC as the medical group while the FAQ names Lion MD.
Medicines listed
  • Semaglutide (compounded, injectable and oral dissolving tablet)
  • Tirzepatide (compounded, injectable and oral dissolving tablet)
  • Ozempic (brand-name)
  • Wegovy (brand-name)
  • Mounjaro (brand-name)
Insurance
No insurance support listed
Consultation
Included
Shipping
Free expedited
States
Availability depends on the patient's state, the service and clinician eligibility under the terms reviewed October 8, 2026; no all-state GLP-1 service list was verified. Confirm your state before paying.
Cancellation
All sales final. The terms say medical consult fees are not eligible for a refund and prescription products cannot be returned, and no cancellation or auto-renewal clause appears in them, yet the about page still shows a Money Back Guarantee badge with no terms attached.

Compounded medicines are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality before they are sold. Read the FDA's explanation of the risks.

MEDGm vs SynergyRx: common questions

Is MEDGm or SynergyRx cheaper?

At least one headline price is a starting, introductory, prepaid or partial figure, so neither is simply cheaper.

  • MEDGm$169/mo equivalent$2,028 upfront for 12 months; applicable taxes may add to the bill
  • SynergyRxfrom $199/mostarting price

Which is better, MEDGm or SynergyRx?

Neither wins outright on our scores, so the better one is the one that fits your medicine, budget and care needs.

Do MEDGm and SynergyRx offer brand-name medication?

MEDGm and SynergyRx both list brand-name and compounded medication.

Compounded medications are not FDA-approved. Your prescriber decides which medicine suits you.

Do MEDGm and SynergyRx take insurance?

Coverage depends on your plan and prescription, so read each provider's insurance terms.

Confirm coverage for your exact plan and prescription before you pay.

Where these facts come from

MEDGm:prices checked October 9, 2026.Read our MEDGm review

SynergyRx:prices checked September 3, 2026, score evidence assessed October 16, 2026.SynergyRx pricing and sources

We score on a published methodology, and partnership never changes a score or a fact here.

What should you compare next?

Both MEDGm and SynergyRx start above the cheapest complete recurring program we track. Across all 39 providers in our index, the lowest price that includes the medicine, consultation and shipping is Eden Health GLP-1 at $99/mo, checked August 28, 2026. This is a price fact, not a treatment recommendation. Compare every program by its complete price

MEDGm reviewSynergyRx prices and sourcesAll comparisonsFind your match

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