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Sesame Care vs Trimi Health: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice
54 providers verified independently·Independent researchHow we rank →

Short answer: Sesame Care scores higher on our rubric, 7.9/10 against 4.2/10. Full reasoning, pricing and the cases where the other one wins are below.

Sesame Care beats Trimi Health overall, scoring 7.9/10 vs 4.2/10. Published pricing is not a like-for-like monthly comparison: Sesame Care is published $99/mo; total not verified; Trimi Health is $175/mo month-to-month. Choose Sesame Care for users who want cheap fda-approved brand-name glp-1 access ($149-349/mo wegovy and zepbound via success by sesame), or insured patients who just need a prescriber. Choose Trimi Health for cash-pay patients who want the cheapest flat-price compounded semaglutide we track ($99/mo on the annual plan) and will accept a weak trustpilot record plus no-pro-rating cancellation terms in exchange.

A side-by-side look at Sesame Care and Trimi Health to help you decide. We compare them on:

  • Starting price per month
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for
Higher Rated

Sesame Care

#5 of 54
7.9/10

Telehealth marketplace offering both a low-cost consultation model ($25/visit) and the new Success by Sesame membership program ($59/mo on 3/6/12-month plans), which coordinates access to FDA-approved brand-name GLP-1 medications including Foundayo (orforglipron), Wegovy pen and pill, and Zepbound. Medication is billed separately.

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Trimi Health

#52 of 54
4.2/10

Telehealth platform for compounded semaglutide and tirzepatide. Weekly injections in vial-and-syringe format only, no pens, no oral option. Pricing is flat across all doses, with the consult and overnight shipping included. Prescriptions route through the Arora Health medical group (Dr. Sean Arora MD, medical director) and are filled by VialsRx and GreenwichRx, the same backend that powers Telos RX. Founded May 2024 per the site's own schema markup; no legal entity suffix or street address is disclosed.

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FeatureSesame CareTrimi Health
Our Score7.9/104.2/10
Headline Pricepublished $99/mo; total not verified$175/mo month-to-month
Medication TypeBothCompounded
Insurance AcceptedYesNo
Best ForUsers who want cheap FDA-approved brand-name GLP-1 access ($149-349/mo Wegovy and Zepbound via Success by Sesame), or insured patients who just need a prescriberCash-pay patients who want the cheapest flat-price compounded semaglutide we track ($99/mo on the annual plan) and will accept a weak Trustpilot record plus no-pro-rating cancellation terms in exchange
Watch out forTwo distinct products (pay-per-visit vs the Success membership) sit side by side, so decide which you're buying before checkoutTrustpilot FELL from 4.6 earlier in 2026 to 3.4 across 71 reviews, ranking #62 of 70 in its category, recurring complaints cite account closures and withheld refunds
Ranking#5#52
Get startedVisit Sesame CareVisit Trimi Health

Pros & Cons Compared

Sesame Care

Pros

  • +Success by Sesame program launched 2026, $59/mo on a 3/6/12-month plan, includes labs, unlimited messaging, and provider choice; medication is separate
  • +Brand-name cash pricing is competitive, Wegovy pen $199 intro / $349 ongoing, Zepbound vial $299, Wegovy pill $149
  • +Foundayo (Lilly's FDA-approved oral GLP-1) available as of April 2026 at $149/mo
  • +Original pay-per-visit model still available at $25/consultation for users who just need a prescriber

Cons

  • Two distinct products (pay-per-visit vs the Success membership) sit side by side, so decide which you're buying before checkout
  • The $59/mo Success by Sesame rate requires a 3-month minimum commitment; month-to-month is available at $99/mo if you don't want to commit
  • Compounded meds are de-emphasized in the current marketing, the platform now leads with FDA-approved brand-name paths
  • A marketplace rather than a concierge, expect less hand-holding than dedicated subscription platforms

Trimi Health

Pros

  • +$99/mo compounded semaglutide on the annual plan (billed $1,188 once yearly) is among the cheapest flat recurring rates we track; tirzepatide annual is $125/mo ($1,500 yearly)
  • +Flat pricing across all doses, your monthly price does not rise as your dose titrates up
  • +Consult and overnight shipping included in the plan price, no add-on fees; HSA/FSA accepted, Klarna and Affirm financing available
  • +Named medical director, Dr. Sean Arora MD of the Arora Health medical group, most compounded-only platforms name no one
  • +Compounding pharmacies named: VialsRx (TX license #35264, site-claimed) and GreenwichRx, most competitors do not name theirs
  • +Available in all 50 states plus DC per trytrimi.com/states
  • +6-month money-back weight-loss promise published (conditions apply, read them before counting on it)

Cons

  • Trustpilot FELL from 4.6 earlier in 2026 to 3.4 across 71 reviews, ranking #62 of 70 in its category, recurring complaints cite account closures and withheld refunds
  • Once a prescription is signed, payments are final, no pro-rating, cancelling an annual plan mid-year forfeits the remainder. Full refund is available only BEFORE the prescription is signed
  • No legal entity disclosed, the site identifies only 'Trimi Health' with no LLC/Inc suffix and no street address (New York appears only in the site's schema markup)
  • Vial-and-syringe format only, no autoinjector pens, no oral option, no brand-name medications
  • LegitScript certification claimed but we could not verify it against LegitScript's registry
  • Mandatory arbitration clause in the terms
  • Retatrutide and orforglipron are listed as 'Preparing', roadmap items, not available today, do not enroll expecting them
  • Shares its medical group (Arora Health) and pharmacy (VialsRx) with Telos RX, a white-label backend relationship neither brand discloses on its own site

Our Verdict

Sesame Care edges out Trimi Health with a score of 7.9/10 vs 4.2/10. Published pricing is not a like-for-like monthly comparison: Sesame Care is published $99/mo; total not verified; Trimi Health is $175/mo month-to-month. Sesame Care accepts insurance, which can significantly reduce your out-of-pocket costs. Sesame Care offers both brand-name and compounded medications, giving you more flexibility.

Try Trimi Health

Headline price: $175/mo month-to-month

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