Independent provider comparison
Updated September 23, 2026
Sesame Carepublished $99/mo; total not verified · Brandvs
Trimi Health$175/mo month-to-month · CompoundedSesame Care vs Trimi Health: Which GLP-1 provider is better?
A side-by-side look at total cost, medication format, care, commitment and the situations where each option makes more sense.
The decision
Which should you choose, Sesame Care or Trimi Health?
Short answer: Sesame Care scores higher on our published rubric, 7.9/10 against 4.2/10. Published pricing is not a like-for-like monthly comparison: Sesame Care is published $99/mo; total not verified; Trimi Health is $175/mo month-to-month.
Consider Sesame Care if
Users who want cheap FDA-approved brand-name GLP-1 access ($149-349/mo Wegovy and Zepbound via Success by Sesame), or insured patients who just need a prescriber.
Consider Trimi Health if
Cash-pay patients who want the cheapest flat-price compounded semaglutide we track ($99/mo on the annual plan) and will accept a Trustpilot rating the platform has withheld for a guidelines breach, plus no-pro-rating cancellation terms, in exchange.
Scores follow our published methodology. Partnership status does not change the score or the factual comparison.
Cost
First charge, renewal and commitment
Treatment
Medication, form and approval status
Care
Clinical review and ongoing support
Terms
Cancellation and material cautions
Sesame Care
#3 of 36Best for users who want cheap fda-approved brand-name glp-1 access ($149-349/mo wegovy and zepbound via success by sesame), or insured patients who just need a prescriber.
Visit Sesame CareTrimi Health
#34 of 36Best for cash-pay patients who want the cheapest flat-price compounded semaglutide we track ($99/mo on the annual plan) and will accept a trustpilot rating the platform has withheld for a guidelines breach, plus no-pro-rating cancellation terms, in exchange.
Visit Trimi HealthSide by side
Sesame Care vs Trimi Health at a glance
Compare the price unit as well as the number. A medication-only price, prepaid monthly equivalent and complete recurring program are not the same thing.
| Feature | Sesame Care | Trimi Health |
|---|---|---|
| Our Score | 7.9/10 | 4.2/10 |
| Headline Price | published $99/mo; total not verified | $175/mo month-to-month |
| Medication Type | Brand | Compounded |
| Insurance Accepted | Yes | No |
| Best For | Users who want cheap FDA-approved brand-name GLP-1 access ($149-349/mo Wegovy and Zepbound via Success by Sesame), or insured patients who just need a prescriber | Cash-pay patients who want the cheapest flat-price compounded semaglutide we track ($99/mo on the annual plan) and will accept a Trustpilot rating the platform has withheld for a guidelines breach, plus no-pro-rating cancellation terms, in exchange |
| Watch out for | Sesame runs three separate routes under one brand: the Success by Sesame weight loss subscription, EverydayRx for diabetes, and one-off visits from $34. Check which one you are signing up for before you pay. | Trustpilot has withheld Trimi's star rating for a breach of its review guidelines and says it removed a number of fake reviews. Of the 55 reviews displayed, 64 percent are one star (checked 2026-09-23). Recent reviewers report fulfillment, refund and certificate-of-analysis concerns; these individual accounts do not establish medication quality |
| Ranking | #3 | #34 |
| Get started | Visit Sesame Care | Visit Trimi Health |
Trade-offs
Strengths and cautions compared
Sesame Care
Pros
- +Success by Sesame is $59/mo on the 12-month commitment and includes provider visits, unlimited messaging and provider choice; lab work is covered only at Quest Diagnostics and not in AZ, HI, ND, NJ, NY, OK, RI, SD or WY, where lab fees are extra; medication is separate
- +Brand-name cash pricing is competitive, Wegovy pen $199 intro / $349 ongoing, Zepbound vial $299, Wegovy pill $149
- +Foundayo (Lilly's FDA-approved oral GLP-1) available as of April 2026 at $149/mo
1 more documented strengths
- +The pay-per-visit route is still there, with visits starting at $34, for users who just need a prescriber
Cons
- −Sesame runs three separate routes under one brand: the Success by Sesame weight loss subscription, EverydayRx for diabetes, and one-off visits from $34. Check which one you are signing up for before you pay.
- −The $59/mo Success by Sesame rate applies only on a 12-month commitment. The 3-month plan works out near $79/mo and the 6-month near $69/mo from the savings the FAQ publishes, and the no-commitment plan is $99 billed every 28 days, which is 13 charges a year.
- −There is no compounded option. Sesame states that compounded semaglutide is not currently available through it, so every route here is brand-name and the medication is billed on top of the program fee.
1 more documented cautions
- −A marketplace rather than a concierge, expect less hand-holding than dedicated subscription platforms
Trimi Health
Pros
- +$99/mo compounded semaglutide on the annual plan (billed $1,188 once yearly) is among the cheapest flat recurring rates we track; tirzepatide annual is $125/mo ($1,500 yearly)
- +Flat pricing across all doses, your monthly price does not rise as your dose titrates up
- +Consult and overnight shipping included in the plan price, no add-on fees; HSA/FSA accepted, Klarna and Affirm financing available
4 more documented strengths
- +Two named physicians, Dr. Sean Arora MD (medical director) and Dr. Shannon Arora MD (chief medical officer) of the Arora Health medical group, most compounded-only platforms name no one
- +Trimi names BelieveRx (formerly VialsRx, according to Trimi) and GreenwichRx as its 503A pharmacy partners; check the dispensing pharmacy on your own prescription label
- +Available in all 50 states plus DC per trytrimi.com/states
- +6-month money-back weight-loss promise published (conditions apply, read them before counting on it)
Cons
- −Trustpilot has withheld Trimi's star rating for a breach of its review guidelines and says it removed a number of fake reviews. Of the 55 reviews displayed, 64 percent are one star (checked 2026-09-23). Recent reviewers report fulfillment, refund and certificate-of-analysis concerns; these individual accounts do not establish medication quality
- −Once a prescription is signed, payments are final, no pro-rating, cancelling an annual plan mid-year forfeits the remainder. Full refund is available only BEFORE the prescription is signed
- −The site names New York City as its base but publishes no street address and no legal entity name, calling itself only 'Trimi Health' with no LLC or Inc suffix on its contact, about, terms or FAQ pages (rendered check 2026-09-03)
5 more documented cautions
- −Vial-and-syringe format only, no autoinjector pens, no oral option, no brand-name medications
- −Trimi says it is LegitScript certified on its treatment pages and links to LegitScript's own checker, but that checker page shows no certification record for trytrimi.com (checked 2026-09-03)
- −The terms carry a mandatory arbitration clause and a class action waiver, with a written opt-out available within 30 days of first accepting them
- −The site contradicts itself on commitment: the treatment page FAQ says you can cancel any time with no long-term commitments, while the pricing page and refund policy say the quarterly, 6-month and annual tiers are commitments for their stated term and payments are final once a prescription is issued (checked 2026-09-03)
- −Free overnight shipping only starts counting after clinician review and after the pharmacy compounds the order, so Trimi's own reviews page puts the honest end to end wait at a few days rather than one night (verified 2026-09-03)
Our Verdict
Sesame Care edges out Trimi Health with a score of 7.9/10 vs 4.2/10. Published pricing is not a like-for-like monthly comparison: Sesame Care is published $99/mo; total not verified; Trimi Health is $175/mo month-to-month. Sesame Care accepts insurance, which can significantly reduce your out-of-pocket costs.
Keep narrowing the decision
What should you compare next?
Use the unresolved part of this choice, not a generic related article. These guides own the broader medication, coverage or complete-cost question.
- Pill decisionCompare Wegovy pill prices and accessUse the dedicated guide for dose-specific costs, required memberships and which providers currently list the FDA-approved pill.Continue
- Coverage decisionCheck your GLP-1 insurance pathLook up plan-specific coverage questions before treating a cash price or an insurance route as your final out-of-pocket cost.Continue
- Cost decisionCompare complete recurring program costsSee which prices include medication, clinical care and shipping, and which headline amounts require another fee or commitment.Continue
Reviews and pricing sources
Related comparisons
More head-to-head comparisons involving Sesame Care and Trimi Health.
Not comparing, just asking? Quick answers to the most-asked GLP-1 questions →
- Compare Sesame Care and Foundpublished $148/mo; total not verified
- Compare Sesame Care and Hers$188 first month, then $298/mo
- Compare Sesame Care and Sprout Healthfrom $110/mo
- Compare Trimi Health and HealthRXfrom $99/mo
- Compare Trimi Health and Collectivefrom $59/mo + $199/year membership after 21 days
- Compare Trimi Health and Ro$149/mo membership + medication
Not sure which one is right for you?
Answer a few quick questions and we'll match you to the best GLP-1 provider for your needs. Or keep exploring below.
Still working out whether either one is above board? We check that separately: is Sesame Care legit, with the verification evidence behind each answer.
Our pick of these two: Sesame Care · 7.9/10