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Sesame Care vs TrimRx: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice
54 providers verified independently·Independent researchHow we rank →

Short answer: Sesame Care scores higher on our rubric, 7.9/10 against 5.3/10. Full reasoning, pricing and the cases where the other one wins are below.

Sesame Care beats TrimRx overall, scoring 7.9/10 vs 5.3/10. Published pricing is not a like-for-like monthly comparison: Sesame Care is published $99/mo; total not verified; TrimRx is published $179/mo; total not verified. Choose Sesame Care for users who want cheap fda-approved brand-name glp-1 access ($149-349/mo wegovy and zepbound via success by sesame), or insured patients who just need a prescriber. Choose TrimRx for cash-pay shoppers willing to verify the exact drug, first-order charge and follow-up price at checkout before authorizing payment.

A side-by-side look at Sesame Care and TrimRx to help you decide. We compare them on:

  • Starting price per month
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for
Higher Rated

Sesame Care

#5 of 54
7.9/10

Telehealth marketplace offering both a low-cost consultation model ($25/visit) and the new Success by Sesame membership program ($59/mo on 3/6/12-month plans), which coordinates access to FDA-approved brand-name GLP-1 medications including Foundayo (orforglipron), Wegovy pen and pill, and Zepbound. Medication is billed separately.

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TrimRx

#47 of 54
5.3/10

Cash-pay compounded GLP-1 provider offering semaglutide and a dual-agonist option it labels 'GLP-1 + GIP.' Its landing advertises a $179 floor, while its terms list semaglutide at $199 for the first order and $299 for follow-ups, and GLP-1 + GIP at $349 then $399. That conflict, plus a corroborated billing and fulfillment complaint pattern, is central to our 5.3/10 score.

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FeatureSesame CareTrimRx
Why each oneThe broadest FDA-approved brand-name GLP-1 menu among low-cost telehealth options, Wegovy pen and pill, Zepbound, Ozempic, Mounjaro, Rybelsus, and Foundayo, coordinated through the new Success by Sesame membership at $59/mo plus medication.A written lost-or-damaged shipment replacement promise and both compounded molecule classes through one intake; neither resolves the first-party price conflict or fulfillment record.
Our Score7.9/105.3/10
Headline Pricepublished $99/mo; total not verifiedpublished $179/mo; total not verified
Medication TypeBothCompounded
Insurance AcceptedYesNo
Best ForUsers who want cheap FDA-approved brand-name GLP-1 access ($149-349/mo Wegovy and Zepbound via Success by Sesame), or insured patients who just need a prescriberCash-pay shoppers willing to verify the exact drug, first-order charge and follow-up price at checkout before authorizing payment
Watch out forTwo distinct products (pay-per-visit vs the Success membership) sit side by side, so decide which you're buying before checkoutThe advertised $179 floor conflicts with TrimRx's own terms: semaglutide is listed at $199 for the first order and $299 for follow-ups; GLP-1 + GIP is $349 first and $399 follow-up. Treat the total as unresolved until checkout
Ranking#5#47
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Pros & Cons Compared

Sesame Care

Pros

  • +Success by Sesame program launched 2026, $59/mo on a 3/6/12-month plan, includes labs, unlimited messaging, and provider choice; medication is separate
  • +Brand-name cash pricing is competitive, Wegovy pen $199 intro / $349 ongoing, Zepbound vial $299, Wegovy pill $149
  • +Foundayo (Lilly's FDA-approved oral GLP-1) available as of April 2026 at $149/mo
  • +Original pay-per-visit model still available at $25/consultation for users who just need a prescriber

Cons

  • Two distinct products (pay-per-visit vs the Success membership) sit side by side, so decide which you're buying before checkout
  • The $59/mo Success by Sesame rate requires a 3-month minimum commitment; month-to-month is available at $99/mo if you don't want to commit
  • Compounded meds are de-emphasized in the current marketing, the platform now leads with FDA-approved brand-name paths
  • A marketplace rather than a concierge, expect less hand-holding than dedicated subscription platforms

TrimRx

Pros

  • +Offers both compounded semaglutide and a compounded GLP-1 + GIP option through one intake
  • +The landing advertises a $179 entry floor, although that figure does not match the medication schedule in the official terms
  • +Onboarding takes under 15 minutes with same-day provider review for most applications
  • +Free medication replacement if your shipment is lost or damaged in transit

Cons

  • The advertised $179 floor conflicts with TrimRx's own terms: semaglutide is listed at $199 for the first order and $299 for follow-ups; GLP-1 + GIP is $349 first and $399 follow-up. Treat the total as unresolved until checkout
  • Trustpilot is 3.6/5 across 5,485 reviews with 32% one-star; BBB rates TrimRx F/not accredited with 728 unanswered and 221 unresolved complaints
  • The same paid-but-no-medication, billing, refund and fulfillment themes recur across BBB and Trustpilot, meeting our rubric's cross-platform -3.0 fulfillment-failure threshold
  • Compounded only, no brand-name Wegovy or Zepbound. Compounded drugs are not FDA-approved finished products.
  • No insurance billing and no superbill for out-of-network reimbursement, so treat the monthly price as a pure cash-pay number

Our Verdict

Sesame Care edges out TrimRx with a score of 7.9/10 vs 5.3/10. Published pricing is not a like-for-like monthly comparison: Sesame Care is published $99/mo; total not verified; TrimRx is published $179/mo; total not verified. Sesame Care accepts insurance, which can significantly reduce your out-of-pocket costs. Sesame Care offers both brand-name and compounded medications, giving you more flexibility.

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