Sesame Care vs TrimRx: Which GLP-1 Provider Is Better?
By Iacob Pastina, Independent Researcher
Sesame Care beats TrimRx overall, scoring 7.9/10 vs 7.8/10. Sesame Care is more affordable at $99/mo vs $149/mo. Choose Sesame Care for users who want cheap fda-approved brand-name glp-1 access ($. Choose TrimRx for users who want affordable compounded semaglutide at one flat.
A side-by-side look at Sesame Care and TrimRx to help you decide. We compare them on:
- •Starting price per month
- •Our overall score, out of 10
- •Medication type, brand-name or compounded
- •Whether they accept insurance
- •Who each one is best for
Sesame Care
#7 of 52Telehealth marketplace offering both a low-cost consultation model ($25/visit) and the new Success by Sesame membership program ($59/mo on 3/6/12-month plans) that bundles FDA-approved brand-name GLP-1 medications, including Foundayo (orforglipron), Wegovy pen and pill, and Zepbound.
Visit Sesame CareTrimRx
#11 of 52Budget-friendly compounded GLP-1 provider with straightforward pricing and a focus on accessibility.
Visit TrimRx| Feature | Sesame Care | TrimRx |
|---|---|---|
| Our Score | 7.9/10 | 7.8/10 |
| Starting Price | $99/mo | $149/mo |
| Medication Type | Both | Compounded |
| Insurance Accepted | Yes | No |
| Best For | Users who want cheap FDA-approved brand-name GLP-1 access ($149-349/mo Wegovy and Zepbound via Success by Sesame), or insured patients who just need a prescriber | Users who want affordable compounded semaglutide at one flat, all-inclusive price |
| Ranking | #7 | #11 |
| Get started | Visit Sesame Care | Visit TrimRx |
Pros & Cons Compared
Sesame Care
Pros
- +Success by Sesame program launched 2026, $59/mo on a 3/6/12-month plan, bundles labs, unlimited messaging, and provider choice
- +Brand-name cash pricing is competitive, Wegovy pen $199 intro / $349 ongoing, Zepbound vial $299, Wegovy pill $149
- +Foundayo (Lilly's FDA-approved oral GLP-1) available as of April 2026 at $149/mo
- +Original pay-per-visit model still available at $25/consultation for users who just need a prescriber
Cons
- −Two distinct products (pay-per-visit vs the Success membership) sit side by side, so decide which you're buying before checkout
- −The $59/mo Success by Sesame rate requires a 3-month minimum commitment; month-to-month is available at $99/mo if you don't want to commit
- −Compounded meds are de-emphasized in the current marketing, the platform now leads with FDA-approved brand-name paths
- −A marketplace rather than a concierge, expect less hand-holding than dedicated subscription platforms
TrimRx
Pros
- +$149/mo all-inclusive for compounded semaglutide, one of the lowest prices for a full-service program
- +Onboarding takes under 15 minutes with same-day provider review for most applications
- +Free medication replacement if your shipment is lost or damaged in transit
Cons
- −Compounded semaglutide is the only medication, no tirzepatide and no brand-name options. Pick TrimRx only if you already know semaglutide is your drug.
- −No insurance billing and no superbill for out-of-network reimbursement, so treat the $149/mo as a pure cash-pay price
Our Verdict
Sesame Care edges out TrimRx with a score of 7.9/10 vs 7.8/10. If budget is your priority, Sesame Care starts at $99/mo compared to TrimRx's $149/mo. Sesame Care accepts insurance, which can significantly reduce your out-of-pocket costs. Sesame Care offers both brand-name and compounded medications, giving you more flexibility. Choose Sesame Care if you want: users who want cheap fda-approved brand-name glp-1 access ($149-349/mo wegovy and zepbound via success by sesame), or insured patients who just need a prescriber. Choose TrimRx if you want: users who want affordable compounded semaglutide at one flat, all-inclusive price.
Still undecided? Editor's Featured Pick
Yucca Health
$146/mo · 7.7/10 · Compounded
If neither Sesame Care nor TrimRx feels like the right fit, our featured pick across all 52 GLP-1 telehealth providers is Yucca Health. It is not the highest-scored provider in our full rankings. We feature it for its low-friction value: a flat $146/mo that stays the same at every dose.
Read Full Reviews
Related comparisons
Other matchups readers comparing Sesame Care or TrimRx tend to look at next.
- Sesame Care vs Found$129/mo
- Sesame Care vs Hers$199/mo
- Sesame Care vs bmiMD$119/mo
- TrimRx vs Bodybuilding Health+$179/mo
- TrimRx vs Strut Health$149/mo
- TrimRx vs Maximus$150/mo
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