Independent provider comparison

Updated September 21, 2026

Sesame Care vs TrimRx: Which GLP-1 provider is better?

A side-by-side look at total cost, medication format, care, commitment and the situations where each option makes more sense.

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice
36 providers verified independently·Independent researchHow we rank →

The decision

Which should you choose, Sesame Care or TrimRx?

Short answer: Sesame Care scores higher on our published rubric, 7.9/10 against 5.3/10. Published pricing is not a like-for-like monthly comparison: Sesame Care is published $99/mo; total not verified; TrimRx is published $149/mo; total not verified.

Consider Sesame Care if

Users who want cheap FDA-approved brand-name GLP-1 access ($149-349/mo Wegovy and Zepbound via Success by Sesame), or insured patients who just need a prescriber.

Consider TrimRx if

Cash-pay shoppers willing to verify the exact drug, first-order charge and follow-up price at checkout before authorizing payment.

Scores follow our published methodology. Partnership status does not change the score or the factual comparison.

Cost

First charge, renewal and commitment

Treatment

Medication, form and approval status

Care

Clinical review and ongoing support

Terms

Cancellation and material cautions

Higher Rated
Sesame Care logo

Sesame Care

#3 of 36
7.9/10

Best for users who want cheap fda-approved brand-name glp-1 access ($149-349/mo wegovy and zepbound via success by sesame), or insured patients who just need a prescriber.

Visit Sesame Care
TrimRx logo

TrimRx

#27 of 36
5.3/10

Best for cash-pay shoppers willing to verify the exact drug, first-order charge and follow-up price at checkout before authorizing payment.

Visit TrimRx

Side by side

Sesame Care vs TrimRx at a glance

Compare the price unit as well as the number. A medication-only price, prepaid monthly equivalent and complete recurring program are not the same thing.

FeatureSesame CareTrimRx
Why each oneThe broadest FDA-approved brand-name GLP-1 menu among low-cost telehealth options, Wegovy pen and pill, Zepbound, Ozempic, Mounjaro, Rybelsus, and Foundayo, coordinated through the Success by Sesame membership at $59/mo on a 12-month commitment plus medication.
Four compounded products through one intake, injectable and oral, plus a shipping policy that grants a refund if nothing ships within 14 days. Neither resolves the price conflict between its offer page and its terms, nor the fulfillment complaint record.
Our Score7.9/105.3/10
Headline Pricepublished $99/mo; total not verifiedpublished $149/mo; total not verified
Medication TypeBrandBoth
Insurance AcceptedYesNo
Best ForUsers who want cheap FDA-approved brand-name GLP-1 access ($149-349/mo Wegovy and Zepbound via Success by Sesame), or insured patients who just need a prescriber
Cash-pay shoppers willing to verify the exact drug, first-order charge and follow-up price at checkout before authorizing payment
Watch out forSesame runs three separate routes under one brand: the Success by Sesame weight loss subscription, EverydayRx for diabetes, and one-off visits from $34. Check which one you are signing up for before you pay.
The $149 floor on an offer page checked September 3 is not what TrimRx's own terms charge: GLP-1 is listed there at $199 for the first month then $299, and GLP-1 + GIP at $349 then $399. Its homepage advertises a third pair of figures, $179 and $259, so confirm the exact charge at checkout
Ranking#3#27
Get startedVisit Sesame CareVisit TrimRx

Trade-offs

Strengths and cautions compared

Sesame Care

Pros

  • +Success by Sesame is $59/mo on the 12-month commitment and includes provider visits, unlimited messaging and provider choice; lab work is covered only at Quest Diagnostics and not in AZ, HI, ND, NJ, NY, OK, RI, SD or WY, where lab fees are extra; medication is separate
  • +Brand-name cash pricing is competitive, Wegovy pen $199 intro / $349 ongoing, Zepbound vial $299, Wegovy pill $149
  • +Foundayo (Lilly's FDA-approved oral GLP-1) available as of April 2026 at $149/mo
1 more documented strengths
  • +The pay-per-visit route is still there, with visits starting at $34, for users who just need a prescriber

Cons

  • −Sesame runs three separate routes under one brand: the Success by Sesame weight loss subscription, EverydayRx for diabetes, and one-off visits from $34. Check which one you are signing up for before you pay.
  • −The $59/mo Success by Sesame rate applies only on a 12-month commitment. The 3-month plan works out near $79/mo and the 6-month near $69/mo from the savings the FAQ publishes, and the no-commitment plan is $99 billed every 28 days, which is 13 charges a year.
  • −There is no compounded option. Sesame states that compounded semaglutide is not currently available through it, so every route here is brand-name and the medication is billed on top of the program fee.
1 more documented cautions
  • −A marketplace rather than a concierge, expect less hand-holding than dedicated subscription platforms

TrimRx

Pros

  • +One intake covers compounded GLP-1 and GLP-1 + GIP injections plus compounded oral versions of both
  • +The offer page checked September 3 advertised a $149 entry floor for GLP-1 and $249 for GLP-1 + GIP, although neither figure matches the medication schedule in the official terms
  • +The intake is a short online assessment with no video call, and the terms say compounded medication generally ships within 48 business hours of the prescription reaching the pharmacy
1 more documented strengths
  • +A published shipping policy that gives you the right to request a refund if your medication has not shipped within 14 days of the order, whatever the status of the medical review

Cons

  • −The $149 floor on an offer page checked September 3 is not what TrimRx's own terms charge: GLP-1 is listed there at $199 for the first month then $299, and GLP-1 + GIP at $349 then $399. Its homepage advertises a third pair of figures, $179 and $259, so confirm the exact charge at checkout
  • −Trustpilot is 3.6/5 across 5,632 reviews with 32% one star, checked 2026-09-03; BBB rated TrimRx F and not accredited with 728 unanswered and 221 unresolved complaints when we last read the profile on August 14, 2026
  • −The same paid-but-no-medication, billing, refund and fulfillment themes recur across BBB and Trustpilot, meeting our rubric's cross-platform -3.0 fulfillment-failure threshold
3 more documented cautions
  • −TrimRx lists brand Wegovy and Ozempic at $1,149 and brand Zepbound and Mounjaro at $1,249 as in stock, while the footer on those same pages says it does not sell, dispense or ship any branded medication and that you are responsible for filling the prescription at your own pharmacy and cost. Its compounded products are not FDA-approved finished products.
  • −No insurance billing, so treat the monthly price as a pure cash-pay number. TrimRx does accept HSA and FSA cards among its payment methods
  • −A TrimRx offer page checked September 3 promised "we guarantee you'll lose weight or your money back", but a disclaimer lower on the same page says weight loss is not guaranteed, and the terms allow refunds only for medical disqualification, a billing error, or unused prepaid months requested within 28 days (verified 2026-09-03)

Our Verdict

Sesame Care edges out TrimRx with a score of 7.9/10 vs 5.3/10. Published pricing is not a like-for-like monthly comparison: Sesame Care is published $99/mo; total not verified; TrimRx is published $149/mo; total not verified. Sesame Care accepts insurance, which can significantly reduce your out-of-pocket costs. TrimRx offers both brand-name and compounded medications, giving you more flexibility.

Keep narrowing the decision

What should you compare next?

Use the unresolved part of this choice, not a generic related article. These guides own the broader medication, coverage or complete-cost question.

Related comparisons

More head-to-head comparisons involving Sesame Care and TrimRx.

Not comparing, just asking? Quick answers to the most-asked GLP-1 questions →

Not sure which one is right for you?

Answer a few quick questions and we'll match you to the best GLP-1 provider for your needs. Or keep exploring below.

Still working out whether either one is above board? We check that separately: is Sesame Care legit and is TrimRx legit, with the verification evidence behind each answer.