48-week supply; confirm renewal · confirm the full bill · checked Sep 3
Check price for ShedOn Shed's site · partner link
Comparison · updated October 25, 2026
Shed and SkinnyRx differ in what you pay and which medicines they list. Compounded medicines are not FDA-approved.
48-week supply; confirm renewal · confirm the full bill · checked Sep 3
Check price for ShedOn Shed's site · partner link
First month, ask the renewal price · checked Sep 26
Check price for SkinnyRxOn SkinnyRx's site · partner link
These two prices are different kinds of bill, so read the line under each price before you compare them.
Shed and SkinnyRx pay us a commission when you join through our links. That never changes a score, an order or a fact on this page. How we make money
Short answer: Shed and SkinnyRx differ in what you pay and which medicines they list, so the plans below decide it.
Shed is best for
Users who want a price that stays flat as the dose escalates, on a simple compounded GLP-1 program.
SkinnyRx is best for
Cash-pay readers comparing compounded injections and dissolving tablets with a clinician, after confirming the refill bill and evidence for the exact formulation.
The available assessments do not establish a score winner, so choose by the medicine, total cost and care you need.
| Shed | SkinnyRx | |
|---|---|---|
| Price | from $159/mo12-month plan label, 48-week supply; confirm full payment and renewal | $99First month, ask the renewal price |
| Medicine | BothBrand-name and compounded | |
| Needle-free option | BothYes, a pill or other oral form | |
| Insurance | BothNo insurance listed | |
| Consultation | BothIncluded | |
| Shipping | Free | Free (overnight on all orders) |
| Where it ships | All 50 states, not Puerto Rico | 47 for compounded medications (its terms exclude Alabama, Louisiana and Mississippi and bar residents of those states from ordering them); branded offerings may be available in all states |
| Trustpilot | 4.7 / 5 across 1,129 reviews | 4.8 / 5 across 4,100 reviews |
| BBB rating | NR (not rated; not accredited) | Not tracked |
| Our score | 7.9/10 Good | 5/10 Mixed |
| Assessment limits | Checked Oct 16, 2026; some details not published. | Checked Oct 16, 2026; a rating claim didn't match Trustpilot. |
One flat price at any dose. Semaglutide starts at $159/mo and tirzepatide at $239/mo on the advertised 12-month plans, which supply 48 weeks. Confirm the billing and renewal schedule; those advertised rates are not verified annual totals.
Semaglutide is advertised at $159/mo on the 12-month plan, which supplies 48 weeks; $179/mo on the 6-month plan supplies 24 weeks, and the 1-month offer is $199. Billing may be monthly or every 28 days depending on the program. Confirm the full bill and renewal schedule; no annual total is verified.
We checked Shed's prices on September 3, 2026.
A four-product compounded menu with separate injection and dissolving-tablet pages for semaglutide and tirzepatide. Compare the exact formulation, introductory bill and renewal terms; the different routes are not established as clinically equivalent.
$99 is a first month rate quoted on the compounded semaglutide and tirzepatide injection product pages. SkinnyRx does not publish a month two price; its terms say the renewal rate is described during checkout.
We checked SkinnyRx's prices on September 26, 2026.
Strengths
More to watch for
Strengths
More to watch for
Compounded medicines are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality before they are sold. Read the FDA's explanation of the risks.
At least one headline price is a starting, introductory, prepaid or partial figure, so neither is simply cheaper.
Neither wins outright on our scores, so the better one is the one that fits your medicine, budget and care needs.
Shed and SkinnyRx both list brand-name and compounded medication.
Neither Shed nor SkinnyRx lists insurance support.
Shed:prices checked September 3, 2026, score evidence assessed October 16, 2026.Read our Shed review
SkinnyRx:prices checked September 26, 2026, score evidence assessed October 16, 2026.Read our SkinnyRx review
We score on a published methodology, and partnership never changes a score or a fact here.
Before you sign up, read our trust checks: is Shed legit and is SkinnyRx legit.