SkinnyRx vs Strut Health: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice
36 providers verified independently·Independent researchHow we rank →

Short answer: Strut Health scores higher on our rubric, 6.2/10 against 5.3/10. Full reasoning, pricing and the cases where the other one wins are below.

Strut Health beats SkinnyRx overall, scoring 6.2/10 vs 5.3/10. Published pricing is not a like-for-like monthly comparison: SkinnyRx is $99 first month, rises after; Strut Health is from $99/mo. Choose SkinnyRx for users who want a choice of compounded glp-1 format, a weekly injection or a daily tablet taken under the tongue, at a low first month price. Choose Strut Health for users who prefer a needle-free oral semaglutide option at a reasonable price.

A side-by-side look at SkinnyRx and Strut Health to help you decide. We compare them on:

  • Starting price and billing period
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for

SkinnyRx

#28 of 36
5.3/10

Direct-to-consumer telehealth platform operated by Lean Rx, Inc. (Sacramento, CA). Its Treatments menu carries four compounded GLP-1 formats, semaglutide and tirzepatide each as a once-weekly injection or a once-daily tablet taken under the tongue, plus two brand-name oral pills, the Wegovy Pill and the Foundayo Pill, both badged FDA-approved and both shown as Unavailable and offered through a SkinnyRx Membership. Every advertised price is a first month rate. Compounded medications are not sold in Alabama, Louisiana or Mississippi. Cash-pay only with HSA/FSA accepted; does not bill insurance. 4,100+ Trustpilot reviews at 4.8 stars.

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Higher Rated

Strut Health

#23 of 36
6.2/10

Oral-focused GLP-1 provider offering needle-free semaglutide options for users who prefer pills over injections.

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FeatureSkinnyRxStrut Health
Why each oneBoth GLP-1 molecules in both administration routes: semaglutide and tirzepatide, each as a once-weekly injection or a once-daily tablet taken under the tongue. The tirzepatide tablet in particular is a format almost no other DTC platform offers, and the two brand-name oral pills it lists alongside them are currently shown as Unavailable.
Needle-free first: oral compounded semaglutide from $99/mo, one of the lowest oral entry prices anywhere, with oral tirzepatide and auto-refill injectables on the same platform if you switch.
Our Score5.3/106.2/10
Headline Price$99 first month, rises afterfrom $99/mo
Medication TypeBothCompounded
Insurance AcceptedNoNo
Best ForUsers who want a choice of compounded GLP-1 format, a weekly injection or a daily tablet taken under the tongue, at a low first month price
Users who prefer a needle-free oral semaglutide option at a reasonable price
Watch out forEvery advertised price is a first month rate and SkinnyRx does not publish what month two costs. Its terms say the renewal rate is described at checkout, and that discounts may be reversed if you cancel before the end of a promotional or committed term.
Compounded only, no brand-name Wegovy or Zepbound. Strut does not publish formulation-specific pharmacokinetic or comparative outcome evidence for its oral tablets, so their absorption and weight-loss results versus approved injections are unknown.
Ranking#28#23
Get startedVisit SkinnyRxVisit Strut Health

Pros & Cons Compared

SkinnyRx

Pros

  • +Four compounded formats, both molecules as both a weekly injection and a daily tablet taken under the tongue, including the tirzepatide tablet that almost no competitor offers
  • +$99 for the first month on both the compounded semaglutide and the compounded tirzepatide injection, quoted on each product page, among the lowest entry rates in the compounded segment
  • +Fast onboarding: a short online intake, a prescription within 24 hours where no video visit is required, and free overnight shipping on all orders with tracking within 2 business days
  • +4,100+ Trustpilot reviews at 4.8 stars, among the strongest aggregate social-proof signals in the GLP-1 telehealth category

Cons

  • Every advertised price is a first month rate and SkinnyRx does not publish what month two costs. Its terms say the renewal rate is described at checkout, and that discounts may be reversed if you cancel before the end of a promotional or committed term.
  • SkinnyRx names its medical director, Sajad Zalzala, M.D., and names AyaRx as the telemedicine partner behind its medical services, but it does not name the compounding pharmacy that fills prescriptions and it publishes no founders or executive team.
  • Cash-pay only, does not bill commercial insurance, Medicare, or Medicaid. HSA/FSA payments are accepted, which is the main way to soften the cost.
  • Independent reviews flag inconsistent customer-service responsiveness, a real consideration since titration support and dose adjustments run through chat
  • FDA warning letter #717989, issued February 20, 2026 to Lean Rx, Inc. dba SkinnyRx, cites misleading labels and website claims for compounded GLP-1s. It is a labeling/marketing record, not an unsafe-medication finding

Strut Health

Pros

  • +Specializes in oral compounded semaglutide, the go-to for patients who absolutely won't do injections
  • +Needle-free oral semaglutide tablets from $99/mo, one of the lowest oral entry prices in the table, with oral tirzepatide ($199/mo) and auto-refill injectables at a flat $149/mo for either semaglutide or tirzepatide if you switch formats
  • +Clear educational content about oral semaglutide absorption and how to maximize effectiveness
  • +Simple enrollment: online questionnaire, async provider review, medication shipped to your door

Cons

  • Compounded only, no brand-name Wegovy or Zepbound. Strut does not publish formulation-specific pharmacokinetic or comparative outcome evidence for its oral tablets, so their absorption and weight-loss results versus approved injections are unknown.
  • Compounded oral semaglutide is not FDA-approved as a finished product or established as bioequivalent to approved oral or injectable semaglutide; do not infer equivalent dosing or results

Our Verdict

Strut Health edges out SkinnyRx with a score of 6.2/10 vs 5.3/10. Published pricing is not a like-for-like monthly comparison: SkinnyRx is $99 first month, rises after; Strut Health is from $99/mo. SkinnyRx offers both brand-name and compounded medications, giving you more flexibility.

Try SkinnyRx

Headline price: $99 first month, rises after

Visit SkinnyRx

Try Strut Health

Headline price: from $99/mo

Visit Strut Health

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