SkinnyRx vs Willow: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

Willow beats SkinnyRx overall, scoring 8.2/10 vs 7.3/10. SkinnyRx is more affordable at $199/mo vs $299/mo. Choose SkinnyRx for users who want flexibility in compounded glp-1 medication fo. Choose Willow for users who want comprehensive clinical support with flexibili.

A side-by-side comparison of SkinnyRx and Willow covering pricing, scores, medication types, insurance, and more to help you decide.

SkinnyRx

#36 of 47
7.3/10

Direct-to-consumer telehealth platform offering compounded GLP-1 medications across five formats — injectable and sublingual semaglutide, semaglutide tablets, and tirzepatide as either injectable or tablets. Operated by Lean Rx, Inc. (Sacramento, CA). Compounded only — does not prescribe brand-name Wegovy/Zepbound/Ozempic/Mounjaro. Cash-pay only with HSA/FSA accepted; does not bill insurance. 4,100+ Trustpilot reviews at 4.8 stars.

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Higher Rated

Willow

#8 of 47
8.2/10

Personalized GLP-1 weight loss with ongoing clinical support. Compounded semaglutide and tirzepatide only — Willow explicitly does not prescribe brand-name Wegovy or Zepbound. Added oral compounded semaglutide tablets as a non-injectable option.

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FeatureSkinnyRxWillow
Our Score7.3/108.2/10
Starting Price$199/mo$299/mo
Medication TypeCompoundedCompounded
Insurance AcceptedNoNo
Best ForUsers who want flexibility in compounded GLP-1 medication format (injectable, sublingual, or tablet) at a mid-tier price pointUsers who want comprehensive clinical support with flexibility between injectable and oral compounded semaglutide routes
Ranking#36#8

Pros & Cons Compared

SkinnyRx

Pros

  • +Five medication formats — the broadest compounded-GLP-1 menu in DTC telehealth, including the rare oral tirzepatide tablet that almost no competitor offers
  • +$199/mo entry price for both injectable and sublingual semaglutide is competitive in the mid-tier compounded segment
  • +Fast onboarding: 5–10 minute online questionnaire, physician review in 24–48 hours, medication delivered in 3–7 business days with temperature-controlled shipping
  • +4,100+ Trustpilot reviews at 4.8 stars — among the strongest aggregate social-proof signals in the GLP-1 telehealth category

Cons

  • No brand-name FDA-approved options (Wegovy, Zepbound, Ozempic, Mounjaro) — compounded-only model limits patients who want or need an FDA-approved finished product
  • Limited public transparency: founders, executive team, medical director, and specific compounding-pharmacy partners are not named on the public site
  • Cash-pay only — does not bill commercial insurance, Medicare, or Medicaid (HSA/FSA payments accepted)
  • Independent reviews flag inconsistent customer-service responsiveness, which is a real concern for a medication that requires titration support and dose-adjustment dialogue

Willow

Pros

  • +Includes monthly provider check-ins and dose adjustments at no extra cost
  • +Offers both injectable AND oral compounded semaglutide — one of few platforms with a daily oral tablet option
  • +$299/mo all-in for compounded semaglutide with monthly provider support
  • +90%+ patient retention rate after 3 months per their published outcomes data

Cons

  • Compounded-only — no brand-name Wegovy or Zepbound through the platform
  • Tirzepatide pricing reaches $499-$524 at higher doses — starting dose is $399/mo
  • Cash-pay only — no insurance billing, though they provide superbills for FSA/HSA
  • Founded in 2024 — less track record than Ro or Hims, though growth has been fast

Our Verdict

Willow edges out SkinnyRx with a score of 8.2/10 vs 7.3/10. If budget is your priority, SkinnyRx starts at $199/mo compared to Willow's $299/mo. Choose SkinnyRx if you want: users who want flexibility in compounded glp-1 medication format (injectable, sublingual, or tablet) at a mid-tier price point. Choose Willow if you want: users who want comprehensive clinical support with flexibility between injectable and oral compounded semaglutide routes.

Try SkinnyRx

Starting at $199/mo

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Try Willow

Starting at $299/mo

Visit Willow
Top Picks

Three programs our readers click through most.

Eden Health GLP-1

8.9/10
$249/mo·Brand & Compounded

Sesame Care

7.9/10
$59/mo·Brand & Compounded

Sprout Health

8.8/10
$249/mo·Brand & Compounded

Affiliate links — we earn a commission at no extra cost to you. Selection reflects what readers convert through, not editorial endorsement. Full ranking + methodology at glp1picks.com.

Today's Cheapest

Sesame Care — $59/mo