SkinnyRx vs Willow: Which GLP-1 Provider Is Better?
Short answer: Willow scores higher on our rubric, 7.5/10 against 5.3/10. Full reasoning, pricing and the cases where the other one wins are below.
Willow beats SkinnyRx overall, scoring 7.5/10 vs 5.3/10. Published pricing is not a like-for-like monthly comparison: SkinnyRx is $99 first month, rises after; Willow is from $299/mo. Choose SkinnyRx for users who want a choice of compounded glp-1 format, a weekly injection or a daily tablet taken under the tongue, at a low first month price. Choose Willow for users who want comprehensive clinical support with a needle-free daily tablet option on both semaglutide and tirzepatide.
A side-by-side look at SkinnyRx and Willow to help you decide. We compare them on:
- •Starting price and billing period
- •Our overall score, out of 10
- •Medication type, brand-name or compounded
- •Whether they accept insurance
- •Who each one is best for
SkinnyRx
#28 of 36Direct-to-consumer telehealth platform operated by Lean Rx, Inc. (Sacramento, CA). Its Treatments menu carries four compounded GLP-1 formats, semaglutide and tirzepatide each as a once-weekly injection or a once-daily tablet taken under the tongue, plus two brand-name oral pills, the Wegovy Pill and the Foundayo Pill, both badged FDA-approved and both shown as Unavailable and offered through a SkinnyRx Membership. Every advertised price is a first month rate. Compounded medications are not sold in Alabama, Louisiana or Mississippi. Cash-pay only with HSA/FSA accepted; does not bill insurance. 4,100+ Trustpilot reviews at 4.8 stars.
Visit SkinnyRxWillow
#10 of 36Personalized GLP-1 weight loss with ongoing clinical support. The catalogue is compounded semaglutide, compounded tirzepatide and a compounded combination tablet carrying both, with no brand-name Wegovy or Zepbound page anywhere on the site. Daily oral dissolving tablets exist for BOTH molecules alongside the injectables, level with the corresponding injection at the starting doses. Willow serves 36 states, not all 50.
Visit Willow| Feature | SkinnyRx | Willow |
|---|---|---|
| Why each one | Both GLP-1 molecules in both administration routes: semaglutide and tirzepatide, each as a once-weekly injection or a once-daily tablet taken under the tongue. The tirzepatide tablet in particular is a format almost no other DTC platform offers, and the two brand-name oral pills it lists alongside them are currently shown as Unavailable. | The only compounded platform on our index with daily dissolving tablets for BOTH semaglutide and tirzepatide at the injection's starting price, plus a combination tablet carrying the two molecules together, the widest needle-free menu in the compounded category. |
| Our Score | 5.3/10 | 7.5/10 |
| Headline Price | $99 first month, rises after | from $299/mo |
| Medication Type | Both | Compounded |
| Insurance Accepted | No | No |
| Best For | Users who want a choice of compounded GLP-1 format, a weekly injection or a daily tablet taken under the tongue, at a low first month price | Users who want comprehensive clinical support with a needle-free daily tablet option on both semaglutide and tirzepatide |
| Watch out for | Every advertised price is a first month rate and SkinnyRx does not publish what month two costs. Its terms say the renewal rate is described at checkout, and that discounts may be reversed if you cancel before the end of a promotional or committed term. | Compounded-only, no brand-name Wegovy or Zepbound through the platform |
| Ranking | #28 | #10 |
| Get started | Visit SkinnyRx | Visit Willow |
Pros & Cons Compared
SkinnyRx
Pros
- +Four compounded formats, both molecules as both a weekly injection and a daily tablet taken under the tongue, including the tirzepatide tablet that almost no competitor offers
- +$99 for the first month on both the compounded semaglutide and the compounded tirzepatide injection, quoted on each product page, among the lowest entry rates in the compounded segment
- +Fast onboarding: a short online intake, a prescription within 24 hours where no video visit is required, and free overnight shipping on all orders with tracking within 2 business days
- +4,100+ Trustpilot reviews at 4.8 stars, among the strongest aggregate social-proof signals in the GLP-1 telehealth category
Cons
- −Every advertised price is a first month rate and SkinnyRx does not publish what month two costs. Its terms say the renewal rate is described at checkout, and that discounts may be reversed if you cancel before the end of a promotional or committed term.
- −SkinnyRx names its medical director, Sajad Zalzala, M.D., and names AyaRx as the telemedicine partner behind its medical services, but it does not name the compounding pharmacy that fills prescriptions and it publishes no founders or executive team.
- −Cash-pay only, does not bill commercial insurance, Medicare, or Medicaid. HSA/FSA payments are accepted, which is the main way to soften the cost.
- −Independent reviews flag inconsistent customer-service responsiveness, a real consideration since titration support and dose adjustments run through chat
- −FDA warning letter #717989, issued February 20, 2026 to Lean Rx, Inc. dba SkinnyRx, cites misleading labels and website claims for compounded GLP-1s. It is a labeling/marketing record, not an unsafe-medication finding
Willow
Pros
- +Includes monthly provider check-ins and dose adjustments at no extra cost
- +Daily oral tablets for BOTH semaglutide and tirzepatide, one of the only platforms with a needle-free route on both molecules
- +$299/mo covers compounded semaglutide at the starting doses, injectable or tablet, with monthly provider support and no separate consultation fee
- +A US licensed doctor reviews and confirms the prescription the same day, and two-day shipping is free, both stated on the product pages (verified 2026-09-03)
Cons
- −Compounded-only, no brand-name Wegovy or Zepbound through the platform
- −Both headline prices are floors. Tirzepatide starts at $399/mo against $299 for semaglutide, and on the help center pricing article maintenance tirzepatide injections run $499/mo from 8.5 mg, $524/mo at 13.5 mg and $549/mo at 17 mg (checked 2026-09-03)
- −Cash-pay only. Willow does not bill insurance. You pay with an HSA or FSA card at checkout, or pay out of pocket and submit receipts to your insurer yourself, with reimbursement depending on your plan and deductible (checked 2026-09-03)
- −The program auto-renews, and a cancellation has to reach the care team at least two business days before the next processing date to stop a charge. A full refund only applies if you cancel before the prescription goes to the pharmacy, and the informed consent page says orders cannot be cancelled, returned or refunded once shipped (checked 2026-09-03)
Our Verdict
Willow edges out SkinnyRx with a score of 7.5/10 vs 5.3/10. Published pricing is not a like-for-like monthly comparison: SkinnyRx is $99 first month, rises after; Willow is from $299/mo. SkinnyRx offers both brand-name and compounded medications, giving you more flexibility.
Reviews and pricing sources
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Our pick of these two: Willow · 7.5/10