SkinnyRx vs Willow: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher

Reviewed & updated August 14, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

54 providers verified independently·Independent research·How we rank →

Visit SkinnyRx - from $199/mo →or find your match

Willow beats SkinnyRx overall, scoring 7.5/10 vs 5.3/10. Published pricing is not a like-for-like monthly comparison: SkinnyRx is from $199/mo; Willow is from $299/mo. Choose SkinnyRx for users who want flexibility in compounded glp-1 medication fo. Choose Willow for users who want comprehensive clinical support with flexibili.

A side-by-side look at SkinnyRx and Willow to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

SkinnyRx

#48 of 54

5.3/10

Direct-to-consumer telehealth platform offering compounded GLP-1 medications across five formats, injectable and sublingual semaglutide, semaglutide tablets, and tirzepatide as either injectable or tablets. Operated by Lean Rx, Inc. (Sacramento, CA). Compounded only, does not prescribe brand-name Wegovy/Zepbound/Ozempic/Mounjaro. Cash-pay only with HSA/FSA accepted; does not bill insurance. 4,100+ Trustpilot reviews at 4.8 stars.

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Higher Rated

Willow

#20 of 54

7.5/10

Personalized GLP-1 weight loss with ongoing clinical support. Compounded semaglutide and tirzepatide only, Willow explicitly does not prescribe brand-name Wegovy or Zepbound. Added oral compounded semaglutide tablets as a non-injectable option.

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Feature	SkinnyRx	Willow
Why each one	The broadest compounded-GLP-1 menu in DTC telehealth, five medication formats including the uncommon sublingual semaglutide and even rarer oral tirzepatide tablets. Most competitors offer one or two formats; SkinnyRx covers every administration route a compounded patient might prefer.	One of the few compounded-only platforms offering both injectable and daily oral semaglutide tablets, useful for users who want a non-injectable option without leaving the GLP-1 compounded category.
Our Score	5.3/10	7.5/10
Headline Price	from $199/mo	from $299/mo
Medication Type	Compounded	Compounded
Insurance Accepted	No	No
Best For	Users who want flexibility in compounded GLP-1 medication format (injectable, sublingual, or tablet) at a mid-tier price point	Users who want comprehensive clinical support with flexibility between injectable and oral compounded semaglutide routes
Watch out for	No brand-name FDA-approved options (Wegovy, Zepbound, Ozempic, Mounjaro), so patients who want or need an FDA-approved finished product should buy elsewhere	Compounded-only, no brand-name Wegovy or Zepbound through the platform
Ranking	#48	#20
Get started	Visit SkinnyRx	Visit Willow

Pros & Cons Compared

SkinnyRx

Pros

+Five medication formats, the broadest compounded-GLP-1 menu in DTC telehealth, including the rare oral tirzepatide tablet that almost no competitor offers
+$199/mo entry price for both injectable and sublingual semaglutide is competitive in the mid-tier compounded segment
+Fast onboarding: 5-10 minute online questionnaire, physician review in 24-48 hours, medication delivered in 3-7 business days with temperature-controlled shipping
+4,100+ Trustpilot reviews at 4.8 stars, among the strongest aggregate social-proof signals in the GLP-1 telehealth category

Cons

−No brand-name FDA-approved options (Wegovy, Zepbound, Ozempic, Mounjaro), so patients who want or need an FDA-approved finished product should buy elsewhere
−Light public disclosure: founders, executive team, medical director, and specific compounding-pharmacy partners are not named on the public site, ask support before enrolling if provenance matters to you
−Cash-pay only, does not bill commercial insurance, Medicare, or Medicaid. HSA/FSA payments are accepted, which is the main way to soften the cost.
−Independent reviews flag inconsistent customer-service responsiveness, a real consideration since titration support and dose adjustments run through chat
−FDA warning letter #717989, issued February 20, 2026 to Lean Rx, Inc. dba SkinnyRx, cites misleading labels and website claims for compounded GLP-1s. It is a labeling/marketing record, not an unsafe-medication finding

Willow

Pros

+Includes monthly provider check-ins and dose adjustments at no extra cost
+Offers both injectable AND oral compounded semaglutide, one of few platforms with a daily oral tablet option
+$299/mo all-in for compounded semaglutide with monthly provider support
+90%+ patient retention rate after 3 months per their published outcomes data

Cons

−Compounded-only, no brand-name Wegovy or Zepbound through the platform
−Tirzepatide pricing reaches $499-$524 at higher doses, starting dose is $399/mo
−Cash-pay only, no insurance billing, though they provide superbills for FSA/HSA
−Founded in 2024, less track record than Ro or Hims, though growth has been fast

Our Verdict

Willow edges out SkinnyRx with a score of 7.5/10 vs 5.3/10. Published pricing is not a like-for-like monthly comparison: SkinnyRx is from $199/mo; Willow is from $299/mo. Choose SkinnyRx if you want: users who want flexibility in compounded glp-1 medication format (injectable, sublingual, or tablet) at a mid-tier price point. Choose Willow if you want: users who want comprehensive clinical support with flexibility between injectable and oral compounded semaglutide routes.