SkinnyRx vs Willow: Which GLP-1 Provider Is Better?
By Iacob Pastina, Independent Researcher
Willow beats SkinnyRx overall, scoring 7.5/10 vs 7.3/10. SkinnyRx is more affordable at $199/mo vs $299/mo. Choose SkinnyRx for users who want flexibility in compounded glp-1 medication fo. Choose Willow for users who want comprehensive clinical support with flexibili.
A side-by-side look at SkinnyRx and Willow to help you decide. We compare them on:
- •Starting price per month
- •Our overall score, out of 10
- •Medication type, brand-name or compounded
- •Whether they accept insurance
- •Who each one is best for
SkinnyRx
#35 of 53Direct-to-consumer telehealth platform offering compounded GLP-1 medications across five formats, injectable and sublingual semaglutide, semaglutide tablets, and tirzepatide as either injectable or tablets. Operated by Lean Rx, Inc. (Sacramento, CA). Compounded only, does not prescribe brand-name Wegovy/Zepbound/Ozempic/Mounjaro. Cash-pay only with HSA/FSA accepted; does not bill insurance. 4,100+ Trustpilot reviews at 4.8 stars.
Visit SkinnyRxWillow
#24 of 53Personalized GLP-1 weight loss with ongoing clinical support. Compounded semaglutide and tirzepatide only, Willow explicitly does not prescribe brand-name Wegovy or Zepbound. Added oral compounded semaglutide tablets as a non-injectable option.
Visit Willow| Feature | SkinnyRx | Willow |
|---|---|---|
| Our Score | 7.3/10 | 7.5/10 |
| Starting Price | $199/mo | $299/mo |
| Medication Type | Compounded | Compounded |
| Insurance Accepted | No | No |
| Best For | Users who want flexibility in compounded GLP-1 medication format (injectable, sublingual, or tablet) at a mid-tier price point | Users who want comprehensive clinical support with flexibility between injectable and oral compounded semaglutide routes |
| Watch out for | No brand-name FDA-approved options (Wegovy, Zepbound, Ozempic, Mounjaro), so patients who want or need an FDA-approved finished product should buy elsewhere | Compounded-only, no brand-name Wegovy or Zepbound through the platform |
| Ranking | #35 | #24 |
| Get started | Visit SkinnyRx | Visit Willow |
Pros & Cons Compared
SkinnyRx
Pros
- +Five medication formats, the broadest compounded-GLP-1 menu in DTC telehealth, including the rare oral tirzepatide tablet that almost no competitor offers
- +$199/mo entry price for both injectable and sublingual semaglutide is competitive in the mid-tier compounded segment
- +Fast onboarding: 5-10 minute online questionnaire, physician review in 24-48 hours, medication delivered in 3-7 business days with temperature-controlled shipping
- +4,100+ Trustpilot reviews at 4.8 stars, among the strongest aggregate social-proof signals in the GLP-1 telehealth category
Cons
- −No brand-name FDA-approved options (Wegovy, Zepbound, Ozempic, Mounjaro), so patients who want or need an FDA-approved finished product should buy elsewhere
- −Light public disclosure: founders, executive team, medical director, and specific compounding-pharmacy partners are not named on the public site, ask support before enrolling if provenance matters to you
- −Cash-pay only, does not bill commercial insurance, Medicare, or Medicaid. HSA/FSA payments are accepted, which is the main way to soften the cost.
- −Independent reviews flag inconsistent customer-service responsiveness, a real consideration since titration support and dose adjustments run through chat
Willow
Pros
- +Includes monthly provider check-ins and dose adjustments at no extra cost
- +Offers both injectable AND oral compounded semaglutide, one of few platforms with a daily oral tablet option
- +$299/mo all-in for compounded semaglutide with monthly provider support
- +90%+ patient retention rate after 3 months per their published outcomes data
Cons
- −Compounded-only, no brand-name Wegovy or Zepbound through the platform
- −Tirzepatide pricing reaches $499-$524 at higher doses, starting dose is $399/mo
- −Cash-pay only, no insurance billing, though they provide superbills for FSA/HSA
- −Founded in 2024, less track record than Ro or Hims, though growth has been fast
Our Verdict
Willow edges out SkinnyRx with a score of 7.5/10 vs 7.3/10. If budget is your priority, SkinnyRx starts at $199/mo compared to Willow's $299/mo. Choose SkinnyRx if you want: users who want flexibility in compounded glp-1 medication format (injectable, sublingual, or tablet) at a mid-tier price point. Choose Willow if you want: users who want comprehensive clinical support with flexibility between injectable and oral compounded semaglutide routes.
Read Full Reviews
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