Independent provider comparison

Updated October 9, 2026

TMates vs TrimRx: Costs, care and treatment fit

A side-by-side look at total cost, medication format, care, commitment and the situations where each option makes more sense.

TrimRX does not practice medicine or prescribe medications. Compounded medications are not FDA-approved and are not evaluated by the FDA for safety or efficacy. Results vary by individual and are not guaranteed. See https://trimrx.com/safety-information for additional information.

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice
37 provider profiles in our comparison·Independent researchHow we rank →

The decision

Which should you choose, TMates or TrimRx?

Short answer: The available assessments do not establish a score winner. Compare medication, full cost, care and commitment to decide which fits your needs. Published pricing is not a like-for-like monthly comparison: TMates is from $158/mo; TrimRx is from $149/mo; offer-page rate; first-order and refill prices differ in the terms.

Consider TMates if

Users who want commitment-discount pricing on compounded GLP-1s (semaglutide $158-$249/mo, tirzepatide $167-$297/mo, medication included) or a $99/mo clinical path to brand Wegovy or Zepbound filled at their own pharmacy.

Consider TrimRx if

Cash-pay shoppers willing to verify the exact drug, first-order charge and follow-up price at checkout before authorizing payment.

Read each assessment label below: missing evidence is not evidence of poor care. Partnership status does not change the score or the factual comparison.

TMates logo

TMates

Assessment limited
7.8/10

This published score has not been reconciled with its recorded evidence. A direct numerical comparison may mislead.

Best for users who want commitment-discount pricing on compounded glp-1s (semaglutide $158-$249/mo, tirzepatide $167-$297/mo, medication included) or a $99/mo clinical path to brand wegovy or zepbound filled at their own pharmacy.

Visit TMates
TrimRx logo

TrimRx

Legacy assessment
5.3/10

This score comes from an earlier or incomplete assessment. It does not establish that this program is better or worse than another.

Best for cash-pay shoppers willing to verify the exact drug, first-order charge and follow-up price at checkout before authorizing payment.

Visit TrimRx

Side by side

TMates vs TrimRx at a glance

Compare the price unit as well as the number. A medication-only price, prepaid monthly equivalent and complete recurring program are not the same thing.

FeatureTMatesTrimRx

Why each one

TMates

Two-archetype platform: (1) compounded GLP-1s with medication included and steep multi-month commitment discounts; (2) cheap $99/mo clinical service for brand Wegovy/Zepbound where you fill the prescription at your own pharmacy.

TrimRx

Four compounded products through one intake, injectable and oral, plus a shipping policy that grants a refund if nothing ships within 14 days. Neither resolves the price conflict between its offer page and its terms, nor the fulfillment complaint record.
Published Assessment7.8/10 Assessment limited5.3/10 Legacy assessment

Assessment limits

TMates

This published score has not been reconciled with its recorded evidence. A direct numerical comparison may mislead.

TrimRx

This score comes from an earlier or incomplete assessment. It does not establish that this program is better or worse than another.
Headline Pricefrom $158/mofrom $149/mo; offer-page rate; first-order and refill prices differ in the terms
Medication TypeBothBoth
Insurance AcceptedYesNo

Best For

TMates

Users who want commitment-discount pricing on compounded GLP-1s (semaglutide $158-$249/mo, tirzepatide $167-$297/mo, medication included) or a $99/mo clinical path to brand Wegovy or Zepbound filled at their own pharmacy

TrimRx

Cash-pay shoppers willing to verify the exact drug, first-order charge and follow-up price at checkout before authorizing payment

Watch out for

TMates

The $99/mo Wegovy or Zepbound tier buys the prescription and provider oversight only. TMates says it does not dispense or ship the drug, and no price for the medication itself appears on its product or category pages, so your own pharmacy bills you separately (checked 2026-09-03).

TrimRx

The $149 floor on an offer page checked September 3 is not what TrimRx's own terms charge: GLP-1 is listed there at $199 for the first month then $299, and GLP-1 + GIP at $349 then $399. Its homepage advertises a third pair of figures, $179 and $259, so confirm the exact charge at checkout
Get startedVisit TMatesVisit TrimRx

Trade-offs

Strengths and cautions compared

TMates

Pros

  • +Clinical-service-only path to brand Wegovy and Zepbound at $99/mo, prescription goes to patient's pharmacy (you fill separately using insurance or cash)
  • +Steep multi-month commitment discounts on compounded sema, $158/mo on 12-month plan ($1,900 upfront) vs $249/mo month-to-month
  • +Same price at all dose levels for compounded, no cost escalation as you titrate up

1 more documented strengths

  • +Phentermine available at $149/mo for patients who benefit from a different appetite-suppressant approach

Cons

  • −The $99/mo Wegovy or Zepbound tier buys the prescription and provider oversight only. TMates says it does not dispense or ship the drug, and no price for the medication itself appears on its product or category pages, so your own pharmacy bills you separately (checked 2026-09-03).
  • −The best compounded rates require prepayment: $1,050 upfront for 6 months, $1,900 for 12. Start at $249 month-to-month if you want to test fit first.
  • −TMates prescribes brand-name but does not dispense it, and is not affiliated with Novo Nordisk (Wegovy) or Eli Lilly (Zepbound). Your own pharmacy fills the Rx.

TrimRx

Pros

  • +One intake covers compounded GLP-1 and GLP-1 + GIP injections plus compounded oral versions of both
  • +The offer page checked September 3 advertised a $149 entry floor for GLP-1 and $249 for GLP-1 + GIP, although neither figure matches the medication schedule in the official terms
  • +Online intake with clinician review; a short telehealth call can be arranged if further consultation is needed. The terms say compounded medication generally ships within 48 business hours of the prescription reaching the pharmacy

1 more documented strengths

  • +A published shipping policy that gives you the right to request a refund if your medication has not shipped within 14 days of the order, whatever the status of the medical review

Cons

  • −The $149 floor on an offer page checked September 3 is not what TrimRx's own terms charge: GLP-1 is listed there at $199 for the first month then $299, and GLP-1 + GIP at $349 then $399. Its homepage advertises a third pair of figures, $179 and $259, so confirm the exact charge at checkout
  • −Trustpilot is 3.6/5 across 5,632 reviews with 32% one star, checked 2026-09-03; BBB rated TrimRx F and not accredited with 728 unanswered and 221 unresolved complaints when we last read the profile on August 14, 2026
  • −The same paid-but-no-medication, billing, refund and fulfillment themes recur across BBB and Trustpilot, meeting our rubric's cross-platform -3.0 fulfillment-failure threshold

3 more documented cautions

  • −TrimRx lists brand Wegovy and Ozempic at $1,149 and brand Zepbound and Mounjaro at $1,249 as in stock, while the footer on those same pages says it does not sell, dispense or ship any branded medication and that you are responsible for filling the prescription at your own pharmacy and cost. Its compounded products are not FDA-approved finished products.
  • −No insurance billing, so treat the monthly price as a pure cash-pay number. TrimRx does accept HSA and FSA cards among its payment methods
  • −An offer page checked September 3 promised weight loss or your money back while also disclaiming guaranteed results. The refund policy is conditional: cancellation before pharmacy transmission allows any applicable policy refund, not a guaranteed treatment trial. Refund requests generally must be made within 28 days of payment

Our Verdict

The available assessments do not establish a score winner between TMates and TrimRx. Compare the medication, full cost, care and commitment that fit your needs. An incomplete assessment is not evidence of poor care. Published pricing is not a like-for-like monthly comparison: TMates is from $158/mo; TrimRx is from $149/mo; offer-page rate; first-order and refill prices differ in the terms. TMates lists insurance support. Confirm coverage for your exact plan and prescription, including any separate program fees.

Keep narrowing the decision

What should you compare next?

Use the unresolved part of this choice, not a generic related article. These guides own the broader medication, coverage or complete-cost question.

Cheapest complete recurring price in our index

Eden Health GLP-1

$99/mo month-to-month · 6.9/10 (Legacy assessment) · Both

Both TMates and TrimRx start above the cheapest complete recurring program we track. Across all 37 providers in our index, the lowest price with affirmative medication, consultation, and shipping inclusion is Eden Health GLP-1 at $99/mo, price checked August 28, 2026. This is a recorded price floor, not a treatment recommendation. Check the plan terms and whether the treatment is appropriate for you with a licensed clinician.

Reviews and pricing sources

Not sure which one is right for you?

Answer a few quick questions and we'll match you to the best GLP-1 provider for your needs. Or keep exploring below.

Still working out whether either one is above board? We check that separately: is TrimRx legit, with the verification evidence behind each answer.