TMates vs TrimRx: Which GLP-1 Provider Is Better?
By Iacob Pastina, Independent Researcher
TMates and TrimRx are tied at 7.8/10. TrimRx is more affordable at $149/mo vs $158/mo. Choose TMates for users who want commitment-discount pricing on compounded glp. Choose TrimRx for users who want affordable compounded semaglutide at one flat.
A side-by-side look at TMates and TrimRx to help you decide. We compare them on:
- •Starting price per month
- •Our overall score, out of 10
- •Medication type, brand-name or compounded
- •Whether they accept insurance
- •Who each one is best for
TMates
#14 of 52Telemedicine platform offering two distinct archetypes: compounded semaglutide and tirzepatide with medication included (commitment pricing $158-$249/mo), and a clinical-service-only path to brand-name Wegovy/Zepbound at $99/mo where the prescription is sent to the patient's pharmacy. Phentermine also available. 2026 expansion added brand-name FDA-approved options.
Visit TMatesTrimRx
#11 of 52Budget-friendly compounded GLP-1 provider with straightforward pricing and a focus on accessibility.
Visit TrimRx| Feature | TMates | TrimRx |
|---|---|---|
| Our Score | 7.8/10 | 7.8/10 |
| Starting Price | $158/mo | $149/mo |
| Medication Type | Both | Compounded |
| Insurance Accepted | Yes | No |
| Best For | Users who want commitment-discount pricing on compounded GLP-1s ($158-$249/mo, medication included) or a $99/mo clinical path to brand Wegovy or Zepbound filled at their own pharmacy | Users who want affordable compounded semaglutide at one flat, all-inclusive price |
| Ranking | #14 | #11 |
| Get started | Visit TMates | Visit TrimRx |
Pros & Cons Compared
TMates
Pros
- +Clinical-service-only path to brand Wegovy and Zepbound at $99/mo, prescription goes to patient's pharmacy (you fill separately using insurance or cash)
- +Steep multi-month commitment discounts on compounded sema, $158/mo on 12-month plan ($1,900 upfront) vs $249/mo month-to-month
- +Same price at all dose levels for compounded, no cost escalation as you titrate up
- +Phentermine available at $149/mo for patients who benefit from a different appetite-suppressant approach
Cons
- −The $99/mo Wegovy/Zepbound tier is the clinical service only. Medication is billed separately at your pharmacy (can be $1,000+/mo cash without insurance). Choose this tier when your insurance covers the drug itself.
- −The best compounded rates require prepayment: $1,050 upfront for 6 months, $1,900 for 12. Start at $249 month-to-month if you want to test fit first.
- −The intake is a 90-second quiz. Fast, but lighter screening than competitors with full medical intakes. Better suited to patients who already know GLP-1 basics.
- −TMates prescribes brand-name but does not dispense it, and is not affiliated with Novo Nordisk (Wegovy) or Eli Lilly (Zepbound). Your own pharmacy fills the Rx.
TrimRx
Pros
- +$149/mo all-inclusive for compounded semaglutide, one of the lowest prices for a full-service program
- +Onboarding takes under 15 minutes with same-day provider review for most applications
- +Free medication replacement if your shipment is lost or damaged in transit
Cons
- −Compounded semaglutide is the only medication, no tirzepatide and no brand-name options. Pick TrimRx only if you already know semaglutide is your drug.
- −No insurance billing and no superbill for out-of-network reimbursement, so treat the $149/mo as a pure cash-pay price
Our Verdict
TMates and TrimRx are closely matched with identical scores of 7.8/10. If budget is your priority, TrimRx starts at $149/mo compared to TMates's $158/mo. TMates accepts insurance, which can significantly reduce your out-of-pocket costs. TMates offers both brand-name and compounded medications, giving you more flexibility. Choose TMates if you want: users who want commitment-discount pricing on compounded glp-1s ($158-$249/mo, medication included) or a $99/mo clinical path to brand wegovy or zepbound filled at their own pharmacy. Choose TrimRx if you want: users who want affordable compounded semaglutide at one flat, all-inclusive price.
Still undecided? Editor's Featured Pick
Yucca Health
$146/mo · 7.7/10 · Compounded
If neither TMates nor TrimRx feels like the right fit, our featured pick across all 52 GLP-1 telehealth providers is Yucca Health. It is not the highest-scored provider in our full rankings. We feature it for its low-friction value: a flat $146/mo that stays the same at every dose.
Read Full Reviews
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