TMates vs TrimRx: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher

Reviewed & updated August 14, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

54 providers verified independently·Independent research·How we rank →

Short answer: TMates scores higher on our rubric, 7.8/10 against 5.3/10. Full reasoning, pricing and the cases where the other one wins are below.

Visit TMates - our pick of these two →or find your match

TMates beats TrimRx overall, scoring 7.8/10 vs 5.3/10. Published pricing is not a like-for-like monthly comparison: TMates is from $158/mo; TrimRx is published $179/mo; total not verified. Choose TMates for users who want commitment-discount pricing on compounded glp-1s ($158-$249/mo, medication included) or a $99/mo clinical path to brand wegovy or zepbound filled at their own pharmacy. Choose TrimRx for cash-pay shoppers willing to verify the exact drug, first-order charge and follow-up price at checkout before authorizing payment.

A side-by-side look at TMates and TrimRx to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

Higher Rated

TMates

#11 of 54

7.8/10

Telemedicine platform offering two distinct archetypes: compounded semaglutide and tirzepatide with medication included (commitment pricing $158-$249/mo), and a clinical-service-only path to brand-name Wegovy/Zepbound at $99/mo where the prescription is sent to the patient's pharmacy. Phentermine also available. 2026 expansion added brand-name FDA-approved options.

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TrimRx

#47 of 54

5.3/10

Cash-pay compounded GLP-1 provider offering semaglutide and a dual-agonist option it labels 'GLP-1 + GIP.' Its landing advertises a $179 floor, while its terms list semaglutide at $199 for the first order and $299 for follow-ups, and GLP-1 + GIP at $349 then $399. That conflict, plus a corroborated billing and fulfillment complaint pattern, is central to our 5.3/10 score.

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Feature	TMates	TrimRx
Why each one	Two-archetype platform: (1) compounded GLP-1s with medication included and steep multi-month commitment discounts; (2) cheap $99/mo clinical service for brand Wegovy/Zepbound where you fill the prescription at your own pharmacy.	A written lost-or-damaged shipment replacement promise and both compounded molecule classes through one intake; neither resolves the first-party price conflict or fulfillment record.
Our Score	7.8/10	5.3/10
Headline Price	from $158/mo	published $179/mo; total not verified
Medication Type	Both	Compounded
Insurance Accepted	Yes	No
Best For	Users who want commitment-discount pricing on compounded GLP-1s ($158-$249/mo, medication included) or a $99/mo clinical path to brand Wegovy or Zepbound filled at their own pharmacy	Cash-pay shoppers willing to verify the exact drug, first-order charge and follow-up price at checkout before authorizing payment
Watch out for	The $99/mo Wegovy/Zepbound tier is the clinical service only. Medication is billed separately at your pharmacy (can be $1,000+/mo cash without insurance). Choose this tier when your insurance covers the drug itself.	The advertised $179 floor conflicts with TrimRx's own terms: semaglutide is listed at $199 for the first order and $299 for follow-ups; GLP-1 + GIP is $349 first and $399 follow-up. Treat the total as unresolved until checkout
Ranking	#11	#47
Get started	Visit TMates	Visit TrimRx

Pros & Cons Compared

TMates

Pros

+Clinical-service-only path to brand Wegovy and Zepbound at $99/mo, prescription goes to patient's pharmacy (you fill separately using insurance or cash)
+Steep multi-month commitment discounts on compounded sema, $158/mo on 12-month plan ($1,900 upfront) vs $249/mo month-to-month
+Same price at all dose levels for compounded, no cost escalation as you titrate up
+Phentermine available at $149/mo for patients who benefit from a different appetite-suppressant approach

Cons

−The $99/mo Wegovy/Zepbound tier is the clinical service only. Medication is billed separately at your pharmacy (can be $1,000+/mo cash without insurance). Choose this tier when your insurance covers the drug itself.
−The best compounded rates require prepayment: $1,050 upfront for 6 months, $1,900 for 12. Start at $249 month-to-month if you want to test fit first.
−The intake is a 90-second quiz. Fast, but lighter screening than competitors with full medical intakes. Better suited to patients who already know GLP-1 basics.
−TMates prescribes brand-name but does not dispense it, and is not affiliated with Novo Nordisk (Wegovy) or Eli Lilly (Zepbound). Your own pharmacy fills the Rx.

TrimRx

Pros

+Offers both compounded semaglutide and a compounded GLP-1 + GIP option through one intake
+The landing advertises a $179 entry floor, although that figure does not match the medication schedule in the official terms
+Onboarding takes under 15 minutes with same-day provider review for most applications
+Free medication replacement if your shipment is lost or damaged in transit

Cons

−The advertised $179 floor conflicts with TrimRx's own terms: semaglutide is listed at $199 for the first order and $299 for follow-ups; GLP-1 + GIP is $349 first and $399 follow-up. Treat the total as unresolved until checkout
−Trustpilot is 3.6/5 across 5,485 reviews with 32% one-star; BBB rates TrimRx F/not accredited with 728 unanswered and 221 unresolved complaints
−The same paid-but-no-medication, billing, refund and fulfillment themes recur across BBB and Trustpilot, meeting our rubric's cross-platform -3.0 fulfillment-failure threshold
−Compounded only, no brand-name Wegovy or Zepbound. Compounded drugs are not FDA-approved finished products.
−No insurance billing and no superbill for out-of-network reimbursement, so treat the monthly price as a pure cash-pay number

Our Verdict

TMates edges out TrimRx with a score of 7.8/10 vs 5.3/10. Published pricing is not a like-for-like monthly comparison: TMates is from $158/mo; TrimRx is published $179/mo; total not verified. TMates accepts insurance, which can significantly reduce your out-of-pocket costs. TMates offers both brand-name and compounded medications, giving you more flexibility.