TMates vs Willow: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher

Reviewed & updated August 14, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

54 providers verified independently·Independent research·How we rank →

Short answer: TMates scores higher on our rubric, 7.8/10 against 7.5/10. Full reasoning, pricing and the cases where the other one wins are below.

Visit TMates - our pick of these two →or find your match

TMates beats Willow overall, scoring 7.8/10 vs 7.5/10. Published pricing is not a like-for-like monthly comparison: TMates is from $158/mo; Willow is from $299/mo. Choose TMates for users who want commitment-discount pricing on compounded glp-1s ($158-$249/mo, medication included) or a $99/mo clinical path to brand wegovy or zepbound filled at their own pharmacy. Choose Willow for users who want comprehensive clinical support with flexibility between injectable and oral compounded semaglutide routes.

A side-by-side look at TMates and Willow to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

Higher Rated

TMates

#11 of 54

7.8/10

Telemedicine platform offering two distinct archetypes: compounded semaglutide and tirzepatide with medication included (commitment pricing $158-$249/mo), and a clinical-service-only path to brand-name Wegovy/Zepbound at $99/mo where the prescription is sent to the patient's pharmacy. Phentermine also available. 2026 expansion added brand-name FDA-approved options.

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Willow

#20 of 54

7.5/10

Personalized GLP-1 weight loss with ongoing clinical support. Compounded semaglutide and tirzepatide only, Willow explicitly does not prescribe brand-name Wegovy or Zepbound. Added oral compounded semaglutide tablets as a non-injectable option.

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Feature	TMates	Willow
Why each one	Two-archetype platform: (1) compounded GLP-1s with medication included and steep multi-month commitment discounts; (2) cheap $99/mo clinical service for brand Wegovy/Zepbound where you fill the prescription at your own pharmacy.	One of the few compounded-only platforms offering both injectable and daily oral semaglutide tablets, useful for users who want a non-injectable option without leaving the GLP-1 compounded category.
Our Score	7.8/10	7.5/10
Headline Price	from $158/mo	from $299/mo
Medication Type	Both	Compounded
Insurance Accepted	Yes	No
Best For	Users who want commitment-discount pricing on compounded GLP-1s ($158-$249/mo, medication included) or a $99/mo clinical path to brand Wegovy or Zepbound filled at their own pharmacy	Users who want comprehensive clinical support with flexibility between injectable and oral compounded semaglutide routes
Watch out for	The $99/mo Wegovy/Zepbound tier is the clinical service only. Medication is billed separately at your pharmacy (can be $1,000+/mo cash without insurance). Choose this tier when your insurance covers the drug itself.	Compounded-only, no brand-name Wegovy or Zepbound through the platform
Ranking	#11	#20
Get started	Visit TMates	Visit Willow

Pros & Cons Compared

TMates

Pros

+Clinical-service-only path to brand Wegovy and Zepbound at $99/mo, prescription goes to patient's pharmacy (you fill separately using insurance or cash)
+Steep multi-month commitment discounts on compounded sema, $158/mo on 12-month plan ($1,900 upfront) vs $249/mo month-to-month
+Same price at all dose levels for compounded, no cost escalation as you titrate up
+Phentermine available at $149/mo for patients who benefit from a different appetite-suppressant approach

Cons

−The $99/mo Wegovy/Zepbound tier is the clinical service only. Medication is billed separately at your pharmacy (can be $1,000+/mo cash without insurance). Choose this tier when your insurance covers the drug itself.
−The best compounded rates require prepayment: $1,050 upfront for 6 months, $1,900 for 12. Start at $249 month-to-month if you want to test fit first.
−The intake is a 90-second quiz. Fast, but lighter screening than competitors with full medical intakes. Better suited to patients who already know GLP-1 basics.
−TMates prescribes brand-name but does not dispense it, and is not affiliated with Novo Nordisk (Wegovy) or Eli Lilly (Zepbound). Your own pharmacy fills the Rx.

Willow

Pros

+Includes monthly provider check-ins and dose adjustments at no extra cost
+Offers both injectable AND oral compounded semaglutide, one of few platforms with a daily oral tablet option
+$299/mo all-in for compounded semaglutide with monthly provider support
+90%+ patient retention rate after 3 months per their published outcomes data

Cons

−Compounded-only, no brand-name Wegovy or Zepbound through the platform
−Tirzepatide pricing reaches $499-$524 at higher doses, starting dose is $399/mo
−Cash-pay only, no insurance billing, though they provide superbills for FSA/HSA
−Founded in 2024, less track record than Ro or Hims, though growth has been fast

Our Verdict

TMates edges out Willow with a score of 7.8/10 vs 7.5/10. Published pricing is not a like-for-like monthly comparison: TMates is from $158/mo; Willow is from $299/mo. TMates accepts insurance, which can significantly reduce your out-of-pocket costs. TMates offers both brand-name and compounded medications, giving you more flexibility.