Independent provider comparison

Updated September 26, 2026

TMates vs Willow: Which GLP-1 provider is better?

A side-by-side look at total cost, medication format, care, commitment and the situations where each option makes more sense.

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice
36 providers verified independently·Independent researchHow we rank →

The decision

Which should you choose, TMates or Willow?

Short answer: TMates scores higher on our published rubric, 7.8/10 against 7.5/10. Published pricing is not a like-for-like monthly comparison: TMates is from $158/mo; Willow is from $299/mo.

Consider TMates if

Users who want commitment-discount pricing on compounded GLP-1s (semaglutide $158-$249/mo, tirzepatide $167-$297/mo, medication included) or a $99/mo clinical path to brand Wegovy or Zepbound filled at their own pharmacy.

Consider Willow if

Users who want comprehensive clinical support with a needle-free daily tablet option on both semaglutide and tirzepatide.

Scores follow our published methodology. Partnership status does not change the score or the factual comparison.

Cost

First charge, renewal and commitment

Treatment

Medication, form and approval status

Care

Clinical review and ongoing support

Terms

Cancellation and material cautions

Higher Rated
TMates logo

TMates

#6 of 36
7.8/10

Best for users who want commitment-discount pricing on compounded glp-1s (semaglutide $158-$249/mo, tirzepatide $167-$297/mo, medication included) or a $99/mo clinical path to brand wegovy or zepbound filled at their own pharmacy.

Visit TMates
Willow logo

Willow

#10 of 36
7.5/10

Best for users who want comprehensive clinical support with a needle-free daily tablet option on both semaglutide and tirzepatide.

Visit Willow

Side by side

TMates vs Willow at a glance

Compare the price unit as well as the number. A medication-only price, prepaid monthly equivalent and complete recurring program are not the same thing.

FeatureTMatesWillow
Why each oneTwo-archetype platform: (1) compounded GLP-1s with medication included and steep multi-month commitment discounts; (2) cheap $99/mo clinical service for brand Wegovy/Zepbound where you fill the prescription at your own pharmacy.
A compounded program with separate semaglutide and tirzepatide dissolving tablets, plus a combination tablet. The format choice may suit a reader who wants to discuss needle-free treatment with a clinician; it does not establish equivalence to an approved pill or injection.
Our Score7.8/107.5/10
Headline Pricefrom $158/mofrom $299/mo
Medication TypeBothCompounded
Insurance AcceptedYesNo
Best ForUsers who want commitment-discount pricing on compounded GLP-1s (semaglutide $158-$249/mo, tirzepatide $167-$297/mo, medication included) or a $99/mo clinical path to brand Wegovy or Zepbound filled at their own pharmacy
Users who want comprehensive clinical support with a needle-free daily tablet option on both semaglutide and tirzepatide
Watch out forThe $99/mo Wegovy or Zepbound tier buys the prescription and provider oversight only. TMates says it does not dispense or ship the drug, and no price for the medication itself appears on its product or category pages, so your own pharmacy bills you separately (checked 2026-09-03).
Compounded-only, no brand-name Wegovy or Zepbound through the platform
Ranking#6#10
Get startedVisit TMatesVisit Willow

Trade-offs

Strengths and cautions compared

TMates

Pros

  • +Clinical-service-only path to brand Wegovy and Zepbound at $99/mo, prescription goes to patient's pharmacy (you fill separately using insurance or cash)
  • +Steep multi-month commitment discounts on compounded sema, $158/mo on 12-month plan ($1,900 upfront) vs $249/mo month-to-month
  • +Same price at all dose levels for compounded, no cost escalation as you titrate up
1 more documented strengths
  • +Phentermine available at $149/mo for patients who benefit from a different appetite-suppressant approach

Cons

  • −The $99/mo Wegovy or Zepbound tier buys the prescription and provider oversight only. TMates says it does not dispense or ship the drug, and no price for the medication itself appears on its product or category pages, so your own pharmacy bills you separately (checked 2026-09-03).
  • −The best compounded rates require prepayment: $1,050 upfront for 6 months, $1,900 for 12. Start at $249 month-to-month if you want to test fit first.
  • −The intake is a 90-second quiz. Fast, but lighter screening than competitors with full medical intakes. Better suited to patients who already know GLP-1 basics.
1 more documented cautions
  • −TMates prescribes brand-name but does not dispense it, and is not affiliated with Novo Nordisk (Wegovy) or Eli Lilly (Zepbound). Your own pharmacy fills the Rx.

Willow

Pros

  • +Includes monthly provider check-ins and dose adjustments at no extra cost
  • +Compounded daily dissolving tablets for semaglutide and tirzepatide, offering a needle-free format to discuss with the prescriber
  • +$299/mo covers compounded semaglutide at the starting doses, injectable or tablet, with monthly provider support and no separate consultation fee
1 more documented strengths
  • +A US licensed doctor reviews and confirms the prescription the same day, and two-day shipping is free, both stated on the product pages (verified 2026-09-03)

Cons

  • −Compounded-only, no brand-name Wegovy or Zepbound through the platform
  • −Both headline prices are floors. Tirzepatide starts at $399/mo against $299 for semaglutide, and on the help center pricing article maintenance tirzepatide injections run $499/mo from 8.5 mg, $524/mo at 13.5 mg and $549/mo at 17 mg (checked 2026-09-03)
  • −Cash-pay only. Willow does not bill insurance. You pay with an HSA or FSA card at checkout, or pay out of pocket and submit receipts to your insurer yourself, with reimbursement depending on your plan and deductible (checked 2026-09-03)
1 more documented cautions
  • −The program auto-renews, and a cancellation has to reach the care team at least two business days before the next processing date to stop a charge. A full refund only applies if you cancel before the prescription goes to the pharmacy, and the informed consent page says orders cannot be cancelled, returned or refunded once shipped (checked 2026-09-03)

Our Verdict

TMates edges out Willow with a score of 7.8/10 vs 7.5/10. Published pricing is not a like-for-like monthly comparison: TMates is from $158/mo; Willow is from $299/mo. TMates accepts insurance, which can significantly reduce your out-of-pocket costs. TMates offers both brand-name and compounded medications, giving you more flexibility.

Keep narrowing the decision

What should you compare next?

Use the unresolved part of this choice, not a generic related article. These guides own the broader medication, coverage or complete-cost question.

Cheapest complete recurring price in our index

Eden Health GLP-1

$99/mo month-to-month, from $34 on a plan · 6.9/10 · Both

Both TMates and Willow start above the cheapest complete recurring program we track. Across all 36 providers in our index, the lowest price with affirmative medication, consultation, and shipping inclusion is Eden Health GLP-1 at $99/mo, price checked August 28, 2026. It scores 6.9/10 and is not the highest-scored provider in our full rankings, so this is a cost floor rather than a recommendation. Worth knowing before you decide.

Try TMates

Headline price: from $158/mo

Visit TMates

Try Willow

Headline price: from $299/mo

Visit Willow

Reviews and pricing sources

Related comparisons

More head-to-head comparisons involving TMates and Willow.

Not comparing, just asking? Quick answers to the most-asked GLP-1 questions →

Not sure which one is right for you?

Answer a few quick questions and we'll match you to the best GLP-1 provider for your needs. Or keep exploring below.

Still working out whether either one is above board? We check that separately: is Willow legit, with the verification evidence behind each answer.

Our pick of these two: TMates · 7.8/10