AgelessRx vs Enhance MD: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher

Reviewed & updated August 14, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

54 providers verified independently·Independent research·How we rank →

Short answer: Enhance MD scores higher on our rubric, 7.8/10 against 7.0/10. Full reasoning, pricing and the cases where the other one wins are below.

Visit Enhance MD - our pick of these two →or find your match

Enhance MD beats AgelessRx overall, scoring 7.8/10 vs 7/10. Published pricing is not a like-for-like monthly comparison: AgelessRx is from $199/mo + $50/mo clinical oversight; Enhance MD is from $212/mo. Choose AgelessRx for longevity-minded users who want glp-1 alongside anti-aging treatments. Choose Enhance MD for budget-conscious users interested in combination therapies.

A side-by-side look at AgelessRx and Enhance MD to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

AgelessRx

#40 of 54

7/10

Longevity-focused telehealth platform combining GLP-1 medications with anti-aging and wellness treatments.

Visit AgelessRx

Higher Rated

Enhance MD

#13 of 54

7.8/10

Affordable telehealth provider offering both compounded and brand-name GLP-1 medications with combination therapy options.

Visit Enhance MD

Feature	AgelessRx	Enhance MD
Why each one	Longevity medicine pioneer offering GLP-1 microdosing alongside anti-aging treatments (NAD+, metformin, rapamycin), no membership fee required.	The most affordable platform offering both medication types plus unique combination therapies (GLP-1 + B12, GLP-1 + NAD+) that no other major provider offers at this price.
Our Score	7/10	7.8/10
Headline Price	from $199/mo + $50/mo clinical oversight	from $212/mo
Medication Type	Both	Both
Insurance Accepted	No	No
Best For	Longevity-minded users who want GLP-1 alongside anti-aging treatments	Budget-conscious users interested in combination therapies
Watch out for	$50/mo clinical oversight fee is charged on top of medication; the published $199 semaglutide path totals $249/mo	Check-ins are patient-initiated rather than scheduled; portal requests are usually answered within 24 hours, but you drive the cadence
Ranking	#40	#13
Get started	Visit AgelessRx	Visit Enhance MD

Pros & Cons Compared

AgelessRx

Pros

+No membership fee, pay only for treatments you choose, unlike platforms that require $50-149/mo subscriptions
+GLP-1 microdosing protocols available from $79/mo, one of only two platforms offering sub-therapeutic doses for metabolic health
+Broader longevity medicine platform with NAD+, metformin, and rapamycin alongside GLP-1 treatment
+Brand-name Zepbound available via LillyDirect partnership starting at $349/mo

Cons

−$50/mo clinical oversight fee is charged on top of medication; the published $199 semaglutide path totals $249/mo
−Longevity medicine framing may overwhelm patients who just want straightforward weight loss medication
−Cold-shipping limitations may affect availability in Alaska and Hawaii

Enhance MD

Pros

+GLP-1 from $49 your first month, then $212/mo, with access to both brand-name and compounded; wafers as low as $84/mo on the 6-month plan
+Offers combination therapies (GLP-1 + B12, GLP-1 + NAD+) for patients wanting enhanced protocols
+Quick asynchronous consultations, most patients approved within 24 hours without video calls
+Flexible dosing: can start at lower doses than standard protocols for sensitive patients

Cons

−Check-ins are patient-initiated rather than scheduled; portal requests are usually answered within 24 hours, but you drive the cadence
−No insurance billing, and customer support runs business days only, no weekends

Our Verdict

Enhance MD edges out AgelessRx with a score of 7.8/10 vs 7/10. Published pricing is not a like-for-like monthly comparison: AgelessRx is from $199/mo + $50/mo clinical oversight; Enhance MD is from $212/mo.