AgelessRx vs Enhance MD: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

52 providers verified independently·Independent researchHow we rank →

Enhance MD beats AgelessRx overall, scoring 7.8/10 vs 7/10. AgelessRx is more affordable at $139/mo vs $212/mo. Choose AgelessRx for longevity-minded users who want glp-1 alongside anti-aging t. Choose Enhance MD for budget-conscious users interested in combination therapies.

A side-by-side look at AgelessRx and Enhance MD to help you decide. We compare them on:

  • Starting price per month
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for

AgelessRx

#46 of 52
7/10

Longevity-focused telehealth platform combining GLP-1 medications with anti-aging and wellness treatments.

Visit AgelessRx
Higher Rated

Enhance MD

#16 of 52
7.8/10

Affordable telehealth provider offering both compounded and brand-name GLP-1 medications with combination therapy options.

Visit Enhance MD
FeatureAgelessRxEnhance MD
Our Score7/107.8/10
Starting Price$139/mo$212/mo
Medication TypeBothBoth
Insurance AcceptedNoNo
Best ForLongevity-minded users who want GLP-1 alongside anti-aging treatmentsBudget-conscious users interested in combination therapies
Ranking#46#16
Get startedVisit AgelessRxVisit Enhance MD

Pros & Cons Compared

AgelessRx

Pros

  • +No membership fee, pay only for treatments you choose, unlike platforms that require $50-149/mo subscriptions
  • +GLP-1 microdosing protocols available from $79/mo, one of only two platforms offering sub-therapeutic doses for metabolic health
  • +Broader longevity medicine platform with NAD+, metformin, and rapamycin alongside GLP-1 treatment
  • +Brand-name Zepbound available via LillyDirect partnership starting at $349/mo

Cons

  • $50/mo clinical oversight fee on top of medication cost, semaglutide totals ~$340/mo, making it one of the pricier options
  • Longevity medicine framing may overwhelm patients who just want straightforward weight loss medication
  • Cold-shipping limitations may affect availability in Alaska and Hawaii

Enhance MD

Pros

  • +GLP-1 from $49 your first month, then $212/mo, with access to both brand-name and compounded; wafers as low as $84/mo on the 6-month plan
  • +Offers combination therapies (GLP-1 + B12, GLP-1 + NAD+) for patients wanting enhanced protocols
  • +Quick asynchronous consultations, most patients approved within 24 hours without video calls
  • +Flexible dosing: can start at lower doses than standard protocols for sensitive patients

Cons

  • Check-ins are patient-initiated rather than scheduled; portal requests are usually answered within 24 hours, but you drive the cadence
  • No insurance billing, and customer support runs business days only, no weekends

Our Verdict

Enhance MD edges out AgelessRx with a score of 7.8/10 vs 7/10. If budget is your priority, AgelessRx starts at $139/mo compared to Enhance MD's $212/mo. Choose AgelessRx if you want: longevity-minded users who want glp-1 alongside anti-aging treatments. Choose Enhance MD if you want: budget-conscious users interested in combination therapies.

Still undecided? Editor's Featured Pick

Yucca Health

$146/mo · 7.7/10 · Compounded

If neither AgelessRx nor Enhance MD feels like the right fit, our featured pick across all 52 GLP-1 telehealth providers is Yucca Health. It is not the highest-scored provider in our full rankings. We feature it for its low-friction value: a flat $146/mo that stays the same at every dose.

Try AgelessRx

Starting at $139/mo

Visit AgelessRx

Try Enhance MD

Starting at $212/mo

Visit Enhance MD

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Featured Partners

Four affiliate partners we feature, we may earn a commission.

Yucca Health

7.7/10
$146/mo·Compounded

Gala

7.2/10
$149/mo·Brand & Compounded

TrimRx

7.8/10
$149/mo·Compounded

SkinnyRx

7.3/10
$199/mo·Compounded

Affiliate links, we earn a commission at no extra cost to you. These are featured partners, prioritized by our affiliate economics, not an editorial "best" ranking. The objective ranking (by methodology score) and full methodology are at glp1picks.com/best.