Plus $199/year membership after 21 days · checked Oct 17
Check price for CollectiveOn Collective's site · partner link
Comparison · updated October 17, 2026
Collective vs SynergyRx: Collective for compounded medication only, SynergyRx for brand-name or compounded options
Collective and SynergyRx differ in what you pay and which medicines they list. Compounded medicines are not FDA-approved.
Confirm the billing interval and additional fees
See prices and terms for SynergyRxThese two prices are different kinds of bill, so read the line under each price before you compare them.
Collective pays us a commission when you join through our links. SynergyRx does not. That never changes a score, an order or a fact on this page. How we make money
Which should you choose, Collective or SynergyRx?
Short answer: Choose SynergyRx if you want brand-name medicine as an option. If that doesn't matter to you, compare their plans below.
Collective is best for
Cash-pay patients planning to stay in treatment long enough for the low flat medication rate to offset the required annual membership.
Choose SynergyRx if
- you want brand-name medicine as an option
- you want a pill or another option without needles
The available assessments do not establish a score winner, so choose by the medicine, total cost and care you need.
By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice
Collective vs SynergyRx side by side
| Collective | SynergyRx | |
|---|---|---|
| Price | from $59/moPlus $199/year membership after 21 days | $199Confirm the billing interval and additional fees |
| Medicine | Compounded only | Brand-name and compounded |
| Needle-free option | Not listed | Yes, a pill or other oral form |
| Insurance | Cash-pay | No insurance listed |
| Consultation | Clinical review and unlimited doctor messaging are included in the required $199/year membership | Included in most plans according to the homepage FAQ, not confirmed for every offer |
| Shipping | Included; two-day express cold shipping is advertised | Free expedited |
| Where it ships | 44 states: AK, AR, AZ, CO, CT, DE, FL, GA, HI, IA, ID, IL, IN, KS, KY, MD, ME, MI, MN, MO, MT, NC, ND, NE, NH, NJ, NM, NV, NY, OH, OK, OR, PA, RI, SC, SD, TN, TX, UT, VA, VT, WI, WV, WY | Availability depends on the patient's state, the service and clinician eligibility under the terms reviewed October 8, 2026; no all-state GLP-1 service list was verified |
| Trustpilot | 4.7 / 5 across 64 reviews | Not tracked |
| Our score | 7.2/10 Fair | 6.2/10 Fair |
| Assessment limits | Checked Sep 15, 2026; some details not published. | Checked Oct 16, 2026; few independent reviews yet. |
What Collective and SynergyRx plans cost
Collective
Very low month-to-month medication pricing that remains flat across doses, funded through a separately disclosed annual membership.
- Collective Membership$199/yrRequired annual membership, free for the first 21 days and then $199 billed annually. It auto-renews unless cancelled.
- Compounded Semaglutide$59$59 billed monthly for medication at any dose, plus required membership free for 21 days then $199/year. Twelve medication payments plus one membership: $907 before any technology transaction fee, which the terms do not price. Not a verified complete bill.
- Compounded Tirzepatide$69$69 billed monthly for medication at any dose, plus required membership free for 21 days then $199/year. Twelve medication payments plus one membership: $1,027 before any technology transaction fee, which the terms do not price. Not a verified complete bill.
How Collective bills
$59/mo is compounded semaglutide medication only. Required membership is free for 21 days, then $199/year. Twelve medication payments plus one membership total $907 for semaglutide or $1,027 for tirzepatide at $69/mo, before any electronic-prescription technology fee the terms allow, which they do not price. These are medication-and-membership subtotals, not the complete bill.
We checked Collective's prices on October 17, 2026.
SynergyRx
Offers oral dissolving tablets for semaglutide and tirzepatide alongside injectable options. Discuss the specific formulation and its supporting evidence with your prescriber rather than assuming the same results across routes.
- Compounded Semaglutide (injection)$199Injectable format, listed as starting at $199 on the products page
- Compounded Semaglutide (oral dissolving tablet)$299Needle-free tablet, listed as starting at $299 on the products page
- Compounded Tirzepatide (injection)$349Injectable format, listed as starting at $349 on the products page
All 6 SynergyRx plans
- Compounded Tirzepatide (oral dissolving tablet)$399Needle-free tablet, listed as starting at $399 on the products page
- Brand-Name Ozempic$499FDA-approved Ozempic with clinical support
- Brand-Name Wegovy/Mounjaro$947FDA-approved brand-name with full clinical support
How SynergyRx bills
Compounded semaglutide injection starts at $199; the oral dissolving tablet starts at $299. Supply duration and billing interval are not publicly confirmed. Most plans include visits and medication, but the full charge depends on the plan, medication and pharmacy. A $100 welcome credit is advertised as applied at checkout with no code needed; confirm how it applies to your offer
We checked SynergyRx's prices on September 3, 2026.
What to watch for with Collective and SynergyRx
Collective
- The $59 and $69 medication headlines exclude a required $199 annual membership after a 21-day trial
- The terms permit a nominal technology transaction fee for each electronic prescription but publish no amount
Collective's strengths, cautions and terms
Strengths
- $59/mo compounded semaglutide and $69/mo compounded tirzepatide, with the medication price advertised as flat at every dose
- Medication is billed month to month rather than through a required multi-month medication prepayment
- Two-day express cold shipping, clinician review, unlimited doctor messaging, and nutrition and lifestyle support are included
- The public site links certificate 50716874 to LegitScript's verification checker
- The legal entity and MDIntegrations clinician-network relationship are disclosed in the legal pages
More to watch for
- No dispensing pharmacy, individual clinician or medical director is publicly named
- Unavailable in Alabama, California, Louisiana, Massachusetts, Mississippi and Washington, according to its FAQ checked October 17, 2026; ask about Washington, D.C. coverage
- The annual membership auto-renews and is generally non-refundable, with no partial-period refunds
- Its long-term GLP-1 service record is not yet confirmed; customer reviews alone do not establish treatment quality
- Cash-pay compounded medications only; no brand-name Wegovy or Zepbound and no insurance or prior-authorization service
- Medicines listed
- Semaglutide (compounded injection)
- Tirzepatide (compounded injection)
- Insurance
- Cash-pay. Collective says medication and membership are HSA/FSA eligible; eligibility and reimbursement depend on the account and expense.
- Consultation
- Clinical review and unlimited doctor messaging are included in the required $199/year membership. The terms also allow a technology transaction fee for an electronic prescription without publishing its amount.
- Shipping
- Included; two-day express cold shipping is advertised
- Prescribers
- Independent US-licensed providers; the privacy policy identifies MDIntegrations and its independent medical-group network as an example clinical partner
- Lab work
- Not required
- States
- 44 states: AK, AR, AZ, CO, CT, DE, FL, GA, HI, IA, ID, IL, IN, KS, KY, MD, ME, MI, MN, MO, MT, NC, ND, NE, NH, NJ, NM, NV, NY, OH, OK, OR, PA, RI, SC, SD, TN, TX, UT, VA, VT, WI, WV, WY. Collective doesn't serve Alabama, California, Louisiana, Massachusetts, Mississippi or Washington, and you should ask about Washington, D.C. We built this list from the FAQ's six-state exclusion list, checked October 17, 2026; a clinician decides your eligibility at intake.
- Cancellation
- Cancel online before the 21-day trial ends to avoid the $199 annual charge. A paid membership continues through its current annual period and is generally non-refundable with no partial-period refund. Products and services are otherwise non-refundable except at CollectiveOS's discretion. If no prescription is issued, the medication order is cancelled and the medication is not charged.
SynergyRx
- The terms publish a Casper, WY address. The October 8, 2026 source check did not confirm a Trustpilot profile on its exact domain; that does not establish that no profile or reviews exist.
- Recorded brand-name starting prices are $499-947, with supply duration and billing interval unconfirmed. Compare the same medication, dose, eligibility and complete charge with the relevant manufacturer's program; a compounded tablet is not an FDA-approved brand equivalent.
SynergyRx's strengths, cautions and terms
Strengths
- Oral dissolving tablets for BOTH semaglutide AND tirzepatide, one of the few platforms with needle-free tirzepatide
- Free expedited shipping included with all orders
- Advertises 24/7 support with unlimited appointments and messaging
- Both compounded and brand-name options available (Ozempic, Wegovy, Mounjaro)
More to watch for
- Founding date and ownership are not shown on the site's contact, about, terms or FAQ pages (rendered check 2026-09-03); the terms disclose only a Delaware corporation. The terms also name Usable Health, PC as the medical group while the FAQ names Lion MD.
- Medicines listed
- Semaglutide (compounded, injectable and oral dissolving tablet)
- Tirzepatide (compounded, injectable and oral dissolving tablet)
- Ozempic (brand-name)
- Wegovy (brand-name)
- Mounjaro (brand-name)
- Insurance
- No insurance support listed
- Consultation
- Included in most plans according to the homepage FAQ, not confirmed for every offer. The terms allow charges to vary by medication and pharmacy; confirm the consultation fee and full total before paying.
- Shipping
- Free expedited
- States
- Availability depends on the patient's state, the service and clinician eligibility under the terms reviewed October 8, 2026; no all-state GLP-1 service list was verified. Confirm your state before paying.
- Cancellation
- All sales final. The terms say medical consult fees are not eligible for a refund and prescription products cannot be returned, and no cancellation or auto-renewal clause appears in them, yet the about page still shows a Money Back Guarantee badge with no terms attached.
Compounded medicines are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality before they are sold. Read the FDA's explanation of the risks.
Collective vs SynergyRx: common questions
Is Collective or SynergyRx cheaper?
At least one headline price is a starting, introductory, prepaid or partial figure, so neither is simply cheaper.
- Collectivefrom $59/moplus $199/year membership after 21 days
- SynergyRx$199Confirm the billing interval and additional fees
Which is better, Collective or SynergyRx?
Neither wins outright on our scores, so the better one is the one that fits your medicine, budget and care needs.
Collective lists compounded medication only, and SynergyRx lists brand-name and compounded medication.
Do Collective and SynergyRx offer brand-name medication?
Collective lists compounded medication only, and SynergyRx lists brand-name and compounded medication.
Compounded medications are not FDA-approved. Your prescriber decides which medicine suits you.
Do Collective and SynergyRx take insurance?
Coverage depends on your plan and prescription, so read each provider's insurance terms.
Confirm coverage for your exact plan and prescription before you pay.
Where these facts come from
Collective:prices checked October 17, 2026.Read our Collective review
SynergyRx:prices checked September 3, 2026, score evidence assessed October 16, 2026.SynergyRx pricing and sources
We score on a published methodology, and partnership never changes a score or a fact here.
What should you compare next?
- Compare complete recurring program costsSee which prices include medication, clinical care and shipping, and which headline amounts require another fee or commitment.
- Compare semaglutide providers and pricesMove from this head-to-head to the broader semaglutide market without confusing compounded products with FDA-approved brands.
- Compare tirzepatide providers and pricesReview provider options, price units and treatment context across the wider tirzepatide market.
Before you sign up, read our trust check: is Collective legit.
Collective reviewSynergyRx prices and sourcesAll comparisonsFind your match