Comparison · updated October 25, 2026

Enhance MD vs Hume Care: Costs, care and treatment fit

Enhance MD and Hume Care differ in what you pay. Compounded medicines are not FDA-approved.

These two prices are different kinds of bill, so read the line under each price before you compare them.

Compare plans and terms

Enhance MD and Hume Care pay us a commission when you join through our links. That never changes a score, an order or a fact on this page. How we make money

Which should you choose, Enhance MD or Hume Care?

Short answer: Enhance MD and Hume Care differ in what you pay, so the plans below decide it.

Enhance MD is best for

Cash-pay shoppers who want the monthly price to stay flat as the dose goes up, and who will do a lab draw and a video visit to get it.

Hume Care is best for

Readers comparing a self-pay GLP-1 program with connected app and body-composition tracking.

The available assessments do not establish a score winner, so choose by the medicine, total cost and care you need.

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

Enhance MD vs Hume Care side by side

Enhance MD and Hume Care compared fact by fact
Enhance MDHume Care
Price$212/4 weeks equivalentPrepaid 48-week plan; confirm the full upfront charge$199/moGLP-1Rx semaglutide offer, billed monthly; prescription-specific extras may apply
MedicineBothCompounded only
Needle-free optionBothNot listed
InsuranceNo insurance listedSelf-pay only under the current terms; not a Medicare or insurance coverage route
ConsultationIncludedIncluded in the membership where applicable, under Hume's current terms
ShippingFreeDelivery is advertised as included; confirm for the selected prescription
Where it ships40 states plus DC: AK, AZ, CA, CO, CT, DC, DE, FL, IA, ID, IL, IN, KS, KY, MA, MD, ME, MI, MN, MT, NC, NE, NH, NJ, NM, NV, NY, OH, OK, OR, PA, RI, SD, TX, UT, VA, VT, WA, WI, WV, WYExcludes Alabama, Arkansas, Louisiana and Mississippi under Hume Care's published coverage policy
Trustpilot4.0 / 5 across 162 reviewsNot tracked
BBB ratingA+ (not accredited)Not tracked
Our score9.4/10 Excellent5.7/10 Mixed
Assessment limitsChecked Oct 16, 2026; some details not published.Checked Sep 15, 2026; some details not published.

What Enhance MD and Hume Care plans cost

Enhance MD

A compounded GLP-1 program with published lab work and a scheduled video visit before prescribing. Core and Advanced are separate molecule options; Elite combines semaglutide and tirzepatide in one formulation. Four-week billing and prepaid 12-, 24- and 48-week plans are not calendar-month or calendar-year prices.

All 11 Enhance MD plans
How Enhance MD bills

$212 advertised four-week equivalent on the prepaid 48-week plan, not a calendar-year subscription; shortest plan is $249 billed every 4 weeks

We checked Enhance MD's prices on August 28, 2026.

Hume Care

How Hume Care bills

The GLP-1Rx page advertises $199/month, billed monthly, with care and medication if prescribed. Terms allow medication, dose, formulation or fulfillment extras, so confirm the full bill for your prescription.

We checked Hume Care's prices on October 8, 2026.

What to watch for with Enhance MD and Hume Care

Enhance MD

  • The $212 headline is a four-week equivalent on a prepaid 48-week plan, not a calendar-year price. The shortest plan costs $249 every four weeks on the GLP-1 Core pricing page (verified 2026-09-03)
  • Compounded only. Every GLP-1 product page states the formulation is not FDA-approved and is compounded under federal Section 503A guidelines, and no brand-name product is sold
Enhance MD's strengths, cautions and terms

Strengths

  • Same price at every dose, so titrating up does not raise the monthly bill. GLP-1 Core is $212 per four-week equivalent on the prepaid 48-week plan and $249 every four weeks on the shortest plan (verified 2026-09-03)
  • The monthly price covers lab work, the video visit with a provider, medication from a partner pharmacy and 2-day shipping, with no separate consultation fee
  • Support is staffed seven days a week, Monday to Friday 8:00 AM to 8:00 PM EDT and Saturday to Sunday 9:00 AM to 5:00 PM EDT, by phone and email
  • Four compounded GLP-1 options including a capped 1 mg microdosing tirzepatide plan from $169 per four weeks on the 48-week plan, plus a full refund of the initial payment if a provider finds you ineligible during onboarding

More to watch for

  • Not nationwide. The FAQ lists 40 states plus DC and leaves out Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina and Tennessee
  • Cash pay with no same-day start: a Quest Diagnostics blood draw and a scheduled video visit both come before a prescription, and no insurance option is shown on the site's pricing, FAQ or terms pages (rendered check 2026-09-03)
Medicines listed
  • Semaglutide (compounded, sold as GLP-1 Core)
  • Tirzepatide (compounded, sold as GLP-1 Advanced)
  • Semaglutide and tirzepatide in one formulation (compounded, sold as GLP-1 Elite)
  • Tirzepatide, 1mg microdosing plan (compounded)
  • NAD+ injections (separate anti-aging product, not a GLP-1)
  • NAD+ wafers (separate anti-aging product, not a GLP-1)
Insurance
No insurance support listed
Consultation
Included
Shipping
Free
States
40 states plus DC: AK, AZ, CA, CO, CT, DC, DE, FL, IA, ID, IL, IN, KS, KY, MA, MD, ME, MI, MN, MT, NC, NE, NH, NJ, NM, NV, NY, OH, OK, OR, PA, RI, SD, TX, UT, VA, VT, WA, WI, WV, WY. Not available in AL, AR, GA, HI, LA, MO, MS, ND, SC, TN. The FAQ says the company is licensed in all 50 states but that it is launching in the listed states only (verified 2026-09-03)
Cancellation
The FAQ says you can pause or cancel your subscription at any time by contacting support, and that membership otherwise renews every 28 days. The 3, 6 and 12-month plans bill every 12, 24 and 48 weeks rather than monthly. Prescription products cannot be returned, and the only refund promised is 100% of the initial payment if a provider finds you ineligible during onboarding (verified 2026-09-03)

Hume Care

  • No verified dispensing pharmacy in the sources reviewed
  • Terms permit prescription-specific extras; ask for dose-level totals and oral formulation details
Hume Care's strengths, cautions and terms

Strengths

  • Consultations are included in the integrated membership under the published terms
  • Native Hume Health iOS app with published Care medication and symptom logging
  • MDI Medical Group PC and a state-specific practitioner directory are publicly identified

More to watch for

  • Responsible clinical leadership and credentials have not been independently verified
  • Independent treatment outcomes and customer-review totals have not been established
Medicines listed
  • Semaglutide (compounded injection)
  • Tirzepatide (compounded injection)
Insurance
Self-pay only under the current terms; not a Medicare or insurance coverage route.
Consultation
Included in the membership where applicable, under Hume's current terms. Certain medications, doses, formulations or fulfillment options can cost extra; Hume must disclose the charge and get your express consent before billing it.
Shipping
Delivery is advertised as included; confirm for the selected prescription
Prescribers
MDI Medical Group PC, the independent clinical network named in Hume's directory. Published practitioner names and license numbers cover Massachusetts, Rhode Island and Vermont; current registry standing was not independently verified.
States
Excludes Alabama, Arkansas, Louisiana and Mississippi under Hume Care's published coverage policy (checked October 8, 2026). Confirm your state's service and treatment eligibility before enrolling.
Cancellation
Cancel before your renewal date in the Subscription section of your account or by emailing support@humecare.com. If you cancel a prepaid plan early, you keep access until the paid term ends but get no pro-rated refund. Two refund exceptions apply: if a physician in Hume's clinical network finds you ineligible for any treatment after your initial evaluation, Hume refunds that membership period within 10 business days, and an included device does not reduce the refund; if Hume ends a prepaid membership without cause, it refunds the unused portion.

Compounded medicines are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality before they are sold. Read the FDA's explanation of the risks.

Enhance MD vs Hume Care: common questions

Is Enhance MD or Hume Care cheaper?

At least one headline price is a starting, introductory, prepaid or partial figure, so neither is simply cheaper.

  • Enhance MD$212/4 weeks equivalentprepaid 48-week plan; confirm the full upfront charge
  • Hume Care$199/moGLP-1Rx semaglutide offer, billed monthly; prescription-specific extras may apply

Which is better, Enhance MD or Hume Care?

Neither wins outright on our scores, so the better one is the one that fits your medicine, budget and care needs.

Do Enhance MD and Hume Care offer brand-name medication?

Enhance MD and Hume Care both list compounded medication.

Compounded medications are not FDA-approved. Your prescriber decides which medicine suits you.

Do Enhance MD and Hume Care take insurance?

Coverage depends on your plan and prescription, so read each provider's insurance terms.

Confirm coverage for your exact plan and prescription before you pay.

Where these facts come from

Enhance MD:prices checked August 28, 2026, score evidence assessed October 16, 2026.Read our Enhance MD review

Hume Care:prices checked October 8, 2026.Read our Hume Care review

We score on a published methodology, and partnership never changes a score or a fact here.

What should you compare next?

Both Enhance MD and Hume Care start above the cheapest complete recurring program we track. Across all 40 providers in our index, the lowest price that includes the medicine, consultation and shipping is Eden Health GLP-1 at $99/mo, checked August 28, 2026. This is a price fact, not a treatment recommendation. Compare every program by its complete price

Before you sign up, read our trust check: is Enhance MD legit.

Enhance MD reviewHume Care reviewAll comparisonsFind your match