Independent provider comparison

Updated September 23, 2026

Enhance MD vs Trimi Health: Which GLP-1 provider is better?

A side-by-side look at total cost, medication format, care, commitment and the situations where each option makes more sense.

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice
36 providers verified independently·Independent researchHow we rank →

The decision

Which should you choose, Enhance MD or Trimi Health?

Short answer: Enhance MD scores higher on our published rubric, 7.8/10 against 4.2/10. Published pricing is not a like-for-like monthly comparison: Enhance MD is from $212/mo; Trimi Health is $175/mo month-to-month.

Consider Enhance MD if

Cash-pay shoppers who want the monthly price to stay flat as the dose goes up, and who will do a lab draw and a video visit to get it.

Consider Trimi Health if

Cash-pay patients who want the cheapest flat-price compounded semaglutide we track ($99/mo on the annual plan) and will accept a Trustpilot rating the platform has withheld for a guidelines breach, plus no-pro-rating cancellation terms, in exchange.

Scores follow our published methodology. Partnership status does not change the score or the factual comparison.

Cost

First charge, renewal and commitment

Treatment

Medication, form and approval status

Care

Clinical review and ongoing support

Terms

Cancellation and material cautions

Higher Rated
Enhance MD logo

Enhance MD

#8 of 36
7.8/10

Best for cash-pay shoppers who want the monthly price to stay flat as the dose goes up, and who will do a lab draw and a video visit to get it.

Visit Enhance MD
Trimi Health logo

Trimi Health

#34 of 36
4.2/10

Best for cash-pay patients who want the cheapest flat-price compounded semaglutide we track ($99/mo on the annual plan) and will accept a trustpilot rating the platform has withheld for a guidelines breach, plus no-pro-rating cancellation terms, in exchange.

Visit Trimi Health

Side by side

Enhance MD vs Trimi Health at a glance

Compare the price unit as well as the number. A medication-only price, prepaid monthly equivalent and complete recurring program are not the same thing.

FeatureEnhance MDTrimi Health
Our Score7.8/104.2/10
Headline Pricefrom $212/mo$175/mo month-to-month
Medication TypeCompoundedCompounded
Insurance AcceptedNoNo
Best ForCash-pay shoppers who want the monthly price to stay flat as the dose goes up, and who will do a lab draw and a video visit to get it
Cash-pay patients who want the cheapest flat-price compounded semaglutide we track ($99/mo on the annual plan) and will accept a Trustpilot rating the platform has withheld for a guidelines breach, plus no-pro-rating cancellation terms, in exchange
Watch out forThe $212/mo headline is the 12-month plan, billed every 48 weeks. Paying month to month costs $249/mo on the GLP-1 Core pricing page (verified 2026-09-03)
Trustpilot has withheld Trimi's star rating for a breach of its review guidelines and says it removed a number of fake reviews. Of the 55 reviews displayed, 64 percent are one star (checked 2026-09-23). Recent reviewers report fulfillment, refund and certificate-of-analysis concerns; these individual accounts do not establish medication quality
Ranking#8#34
Get startedVisit Enhance MDVisit Trimi Health

Trade-offs

Strengths and cautions compared

Enhance MD

Pros

  • +Same price at every dose, so titrating up does not raise the monthly bill. GLP-1 Core is $212/mo on the 12-month plan and $249/mo month to month (verified 2026-09-03)
  • +The monthly price covers lab work, the video visit with a provider, medication from a partner pharmacy and 2-day shipping, with no separate consultation fee
  • +Support is staffed seven days a week, Monday to Friday 8:00 AM to 8:00 PM EDT and Saturday to Sunday 9:00 AM to 5:00 PM EDT, by phone and email
1 more documented strengths
  • +Four compounded GLP-1 options including a capped 1mg microdosing tirzepatide plan at $169/mo, plus a full refund of the initial payment if a provider finds you ineligible during onboarding

Cons

  • −The $212/mo headline is the 12-month plan, billed every 48 weeks. Paying month to month costs $249/mo on the GLP-1 Core pricing page (verified 2026-09-03)
  • −Compounded only. Every GLP-1 product page states the formulation is not FDA-approved and is compounded under federal Section 503A guidelines, and no brand-name product is sold
  • −Not nationwide. The FAQ lists 40 states plus DC and leaves out Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina and Tennessee
1 more documented cautions
  • −Cash pay with no same-day start: a Quest Diagnostics blood draw and a scheduled video visit both come before a prescription, and no insurance option is shown on the site's pricing, FAQ or terms pages (rendered check 2026-09-03)

Trimi Health

Pros

  • +$99/mo compounded semaglutide on the annual plan (billed $1,188 once yearly) is among the cheapest flat recurring rates we track; tirzepatide annual is $125/mo ($1,500 yearly)
  • +Flat pricing across all doses, your monthly price does not rise as your dose titrates up
  • +Consult and overnight shipping included in the plan price, no add-on fees; HSA/FSA accepted, Klarna and Affirm financing available
4 more documented strengths
  • +Two named physicians, Dr. Sean Arora MD (medical director) and Dr. Shannon Arora MD (chief medical officer) of the Arora Health medical group, most compounded-only platforms name no one
  • +Trimi names BelieveRx (formerly VialsRx, according to Trimi) and GreenwichRx as its 503A pharmacy partners; check the dispensing pharmacy on your own prescription label
  • +Available in all 50 states plus DC per trytrimi.com/states
  • +6-month money-back weight-loss promise published (conditions apply, read them before counting on it)

Cons

  • −Trustpilot has withheld Trimi's star rating for a breach of its review guidelines and says it removed a number of fake reviews. Of the 55 reviews displayed, 64 percent are one star (checked 2026-09-23). Recent reviewers report fulfillment, refund and certificate-of-analysis concerns; these individual accounts do not establish medication quality
  • −Once a prescription is signed, payments are final, no pro-rating, cancelling an annual plan mid-year forfeits the remainder. Full refund is available only BEFORE the prescription is signed
  • −The site names New York City as its base but publishes no street address and no legal entity name, calling itself only 'Trimi Health' with no LLC or Inc suffix on its contact, about, terms or FAQ pages (rendered check 2026-09-03)
5 more documented cautions
  • −Vial-and-syringe format only, no autoinjector pens, no oral option, no brand-name medications
  • −Trimi says it is LegitScript certified on its treatment pages and links to LegitScript's own checker, but that checker page shows no certification record for trytrimi.com (checked 2026-09-03)
  • −The terms carry a mandatory arbitration clause and a class action waiver, with a written opt-out available within 30 days of first accepting them
  • −The site contradicts itself on commitment: the treatment page FAQ says you can cancel any time with no long-term commitments, while the pricing page and refund policy say the quarterly, 6-month and annual tiers are commitments for their stated term and payments are final once a prescription is issued (checked 2026-09-03)
  • −Free overnight shipping only starts counting after clinician review and after the pharmacy compounds the order, so Trimi's own reviews page puts the honest end to end wait at a few days rather than one night (verified 2026-09-03)

Our Verdict

Enhance MD edges out Trimi Health with a score of 7.8/10 vs 4.2/10. Published pricing is not a like-for-like monthly comparison: Enhance MD is from $212/mo; Trimi Health is $175/mo month-to-month.

Keep narrowing the decision

What should you compare next?

Use the unresolved part of this choice, not a generic related article. These guides own the broader medication, coverage or complete-cost question.

Cheapest complete recurring price in our index

Eden Health GLP-1

$99/mo month-to-month, from $34 on a plan · 6.9/10 · Both

Both Enhance MD and Trimi Health start above the cheapest complete recurring program we track. Across all 36 providers in our index, the lowest price with affirmative medication, consultation, and shipping inclusion is Eden Health GLP-1 at $99/mo, price checked August 28, 2026. It scores 6.9/10 and is not the highest-scored provider in our full rankings, so this is a cost floor rather than a recommendation. Worth knowing before you decide.

Try Enhance MD

Headline price: from $212/mo

Visit Enhance MD

Try Trimi Health

Headline price: $175/mo month-to-month

Visit Trimi Health

Related comparisons

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