Enhance MD vs Wellorithm: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice
36 providers verified independently·Independent researchHow we rank →

Short answer: Enhance MD scores higher on our rubric, 7.8/10 against 7.4/10. Full reasoning, pricing and the cases where the other one wins are below.

Enhance MD beats Wellorithm overall, scoring 7.8/10 vs 7.4/10. Published pricing is not a like-for-like monthly comparison: Enhance MD is from $212/mo; Wellorithm is from $147/mo. Choose Enhance MD for cash-pay shoppers who want the monthly price to stay flat as the dose goes up, and who will do a lab draw and a video visit to get it. Choose Wellorithm for cash-pay patients who want compounded semaglutide or tirzepatide in a rare oral dissolving tablet format, backed by a 10% weight-loss money-back guarantee and 24/7 support.

A side-by-side look at Enhance MD and Wellorithm to help you decide. We compare them on:

  • Starting price and billing period
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for
Higher Rated

Enhance MD

#8 of 36
7.8/10

Cash-pay telehealth program selling compounded semaglutide, compounded tirzepatide, a formulation containing both, and a low-dose microdosing tirzepatide plan. Every GLP-1 it sells is compounded and not FDA-approved; there is no brand-name option. The price is flat at every dose, $212/mo on the 12-month plan and $249/mo month to month (verified 2026-09-03).

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Wellorithm

#13 of 36
7.4/10

Telehealth platform offering compounded semaglutide and tirzepatide in BOTH injectable and oral dissolving tablet formats, alongside brand-name Wegovy, Ozempic, Zepbound and Mounjaro on their own product pages, plus NAD+ and Sermorelin on the same pricing grid (verified 2026-09-03). A 10% weight-loss guarantee refunds up to four months of program fees if the patient does not lose at least 10% of baseline weight after 16 weeks of medication adherence (terms apply). 28-day recurring billing, non-refundable per-cycle.

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FeatureEnhance MDWellorithm
Why each oneThe most affordable platform offering both medication types plus unique combination therapies (GLP-1 + B12, GLP-1 + NAD+) that no other major provider offers at this price.
The combination of compounded GLP-1 in BOTH injectable and oral dissolving tablet formats AND a 10% weight-loss money-back guarantee, a format breadth and outcome-tied refund policy that few compounded-only platforms offer in combination, paired with the trade-off that no founder or legal entity is named on the site.
Our Score7.8/107.4/10
Headline Pricefrom $212/mofrom $147/mo
Medication TypeCompoundedBoth
Insurance AcceptedNoNo
Best ForCash-pay shoppers who want the monthly price to stay flat as the dose goes up, and who will do a lab draw and a video visit to get it
Cash-pay patients who want compounded semaglutide or tirzepatide in a rare oral dissolving tablet format, backed by a 10% weight-loss money-back guarantee and 24/7 support
Watch out forThe $212/mo headline is the 12-month plan, billed every 48 weeks. Paying month to month costs $249/mo on the GLP-1 Core pricing page (verified 2026-09-03)
Founding year, corporate ownership and the legal entity behind the program are not published on wellorithm.com; the Terms describe it only as 'a Miami-based company' that connects patients with unnamed 'Professional Entities' (verified 2026-09-03). The program page and every medication page do name three partner physicians, and the contact page gives a Miami street address and phone, so the gap is corporate rather than clinical
Ranking#8#13
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Pros & Cons Compared

Enhance MD

Pros

  • +Same price at every dose, so titrating up does not raise the monthly bill. GLP-1 Core is $212/mo on the 12-month plan and $249/mo month to month (verified 2026-09-03)
  • +The monthly price covers lab work, the video visit with a provider, medication from a partner pharmacy and 2-day shipping, with no separate consultation fee
  • +Support is staffed seven days a week, Monday to Friday 8:00 AM to 8:00 PM EDT and Saturday to Sunday 9:00 AM to 5:00 PM EDT, by phone and email
  • +Four compounded GLP-1 options including a capped 1mg microdosing tirzepatide plan at $169/mo, plus a full refund of the initial payment if a provider finds you ineligible during onboarding

Cons

  • The $212/mo headline is the 12-month plan, billed every 48 weeks. Paying month to month costs $249/mo on the GLP-1 Core pricing page (verified 2026-09-03)
  • Compounded only. Every GLP-1 product page states the formulation is not FDA-approved and is compounded under federal Section 503A guidelines, and no brand-name product is sold
  • Not nationwide. The FAQ lists 40 states plus DC and leaves out Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina and Tennessee
  • Cash pay with no same-day start: a Quest Diagnostics blood draw and a scheduled video visit both come before a prescription, and no insurance option is shown on the site's pricing, FAQ or terms pages (rendered check 2026-09-03)

Wellorithm

Pros

  • +Compounded GLP-1 available in BOTH injectable AND oral dissolving tablet formats, semaglutide and tirzepatide each in two formats, broader format menu than most compounded-only platforms
  • +10% weight-loss money-back guarantee: patients who don't lose at least 10% of baseline weight after 16 weeks of medication adherence may be eligible for refund of up to four months of program fees (verified weight documentation required)
  • +Competitive entry pricing, $147/mo compounded semaglutide and $249/mo compounded tirzepatide put Wellorithm near the cheaper end of the compounded market
  • +Short online eligibility quiz, virtual consultation, 24/7 support availability claimed
  • +23,000+ reviews and 4.9-star rating reported (volume is unusually high for this market segment, verify on independent third-party sources before relying on it)
  • +Spring promotion advertised at $147 with free shipping included

Cons

  • Founding year, corporate ownership and the legal entity behind the program are not published on wellorithm.com; the Terms describe it only as 'a Miami-based company' that connects patients with unnamed 'Professional Entities' (verified 2026-09-03). The program page and every medication page do name three partner physicians, and the contact page gives a Miami street address and phone, so the gap is corporate rather than clinical
  • 49 states only, service is unavailable in Louisiana and outside the United States
  • Billing runs on a 28-day recurring cycle and payments are non-refundable once processed, with no proration for partial months; cancel before your next cycle processes to avoid paying for an unused month
  • The weight-loss guarantee has strict eligibility terms: verified weight documentation (doctor attestation or video evidence), prior medication history disclosure, consistent dosing adherence, and refund processed within 30 days of approval, with only fees actually paid refundable and baseline payments non-refundable; document your starting weight from day one if you plan to rely on it
  • Brand-name prices carry conditions the headline figures do not show: the Ozempic and Zepbound pages advertise $1,119 a month at the top and $1,199 a month in the pricing card, and all four brand pages footnote that the figure applies to a 500mg three-month plan paid upfront or through a buy now, pay later program (verified 2026-09-03). Budget for the prepaid plan, not the monthly number

Our Verdict

Enhance MD edges out Wellorithm with a score of 7.8/10 vs 7.4/10. Published pricing is not a like-for-like monthly comparison: Enhance MD is from $212/mo; Wellorithm is from $147/mo. Wellorithm offers both brand-name and compounded medications, giving you more flexibility.

Try Enhance MD

Headline price: from $212/mo

Visit Enhance MD

Try Wellorithm

Headline price: from $147/mo

Visit Wellorithm

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