$212/4 weeks equivalent at Enhance MD
48-week prepay · checked Aug 28
Check price for Enhance MDOn Enhance MD's site · partner link
Comparison · updated October 16, 2026
Enhance MD vs SkinnyRx: Enhance MD for compounded medication only, SkinnyRx for brand-name or compounded options
Enhance MD and SkinnyRx differ in what you pay and which medicines they list. Compounded medicines are not FDA-approved.
First month, ask the renewal price · checked Sep 26
Check price for SkinnyRxOn SkinnyRx's site · partner link
These two prices are different kinds of bill, so read the line under each price before you compare them.
Enhance MD and SkinnyRx pay us a commission when you join through our links. That never changes a score, an order or a fact on this page. How we make money
Which should you choose, Enhance MD or SkinnyRx?
Short answer: Choose SkinnyRx if you want brand-name medicine as an option. If that doesn't matter to you, compare their plans below.
Enhance MD is best for
Cash-pay shoppers who want the monthly price to stay flat as the dose goes up, and who will do a lab draw and a video visit to get it.
Choose SkinnyRx if
- you want brand-name medicine as an option
- you want a pill or another option without needles
- you put weight on customer ratings (4.8 on Trustpilot against 4.0)
The available assessments do not establish a score winner, so choose by the medicine, total cost and care you need.
By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice
Enhance MD vs SkinnyRx side by side
| Enhance MD | SkinnyRx | |
|---|---|---|
| Price | $212/4 weeks equivalentPrepaid 48-week plan; confirm the full upfront charge | $99First month, ask the renewal price |
| Medicine | Compounded only | Brand-name and compounded |
| Needle-free option | Not listed | Yes, a pill or other oral form |
| Insurance | BothNo insurance listed | |
| Consultation | BothIncluded | |
| Shipping | Free | Free (overnight on all orders) |
| Where it ships | 40 states plus DC: AK, AZ, CA, CO, CT, DC, DE, FL, IA, ID, IL, IN, KS, KY, MA, MD, ME, MI, MN, MT, NC, NE, NH, NJ, NM, NV, NY, OH, OK, OR, PA, RI, SD, TX, UT, VA, VT, WA, WI, WV, WY | 47 for compounded medications (its terms exclude Alabama, Louisiana and Mississippi and bar residents of those states from ordering them); branded offerings may be available in all states |
| Trustpilot | 4.0 / 5 across 162 reviews | 4.8 / 5 across 4,100 reviews |
| BBB rating | A+ (not accredited) | Not tracked |
| Our score | 9.4/10 Excellent | 5/10 Mixed |
| Assessment limits | Checked Oct 16, 2026; some details not published. | Checked Oct 16, 2026; a rating claim didn't match Trustpilot. |
What Enhance MD and SkinnyRx plans cost
Enhance MD
A compounded GLP-1 program with published lab work and a scheduled video visit before prescribing. Core and Advanced are separate molecule options; Elite combines semaglutide and tirzepatide in one formulation. Four-week billing and prepaid 12-, 24- and 48-week plans are not calendar-month or calendar-year prices.
- Microdose Tirzepatide$169/4 weeks1 mg a week of compounded tirzepatide, capped rather than increased. $169 per four-week equivalent on the 12-month plan billed every 48 weeks, $179 on the 6-month plan billed every 24 weeks and $189 on the 3-month plan billed every 12 weeks. Medication ships every 12 weeks. The page showed no price for the 1-month option.
- Compounded Semaglutide (12-month plan)$212/4 weeksAdvertised four-week equivalent; prepaid every 48 weeks, not a calendar year
- Compounded Semaglutide (6-month plan)$224/4 weeksAdvertised four-week equivalent; prepaid every 24 weeks, not calendar months
All 11 Enhance MD plans
- Compounded Semaglutide (3-month plan)$237/4 weeksAdvertised four-week equivalent; prepaid every 12 weeks, not calendar months
- Compounded Semaglutide (month-to-month)$249/4 weeksBilled every 4 weeks
- Compounded Tirzepatide (12-month)$280/4 weeks$280 advertised four-week-equivalent rate on the 12-month plan, billed every 48 weeks; confirm the full upfront total before paying.
- Compounded Tirzepatide (6-month)$296/4 weeks$296 advertised four-week-equivalent rate on the 6-month plan, billed every 24 weeks; confirm the full upfront total before paying.
- Compounded Tirzepatide (3-month)$313/4 weeks$313 advertised four-week-equivalent rate on the 3-month plan, billed every 12 weeks; confirm the full upfront total before paying.
- Compounded Tirzepatide (month-to-month)$329/4 weeks$329 billed every 4 weeks on the shortest plan, before any eligible first-order discount.
- Elite Bundle (sema + tirz)$322A compounded formulation containing semaglutide and tirzepatide together; historical $189 introductory price requires confirmation of the current plan and charge
- NAD+ Therapy (subcutaneous)$169NAD+ injection therapy, separate product line, not a GLP-1
How Enhance MD bills
$212 advertised four-week equivalent on the prepaid 48-week plan, not a calendar-year subscription; shortest plan is $249 billed every 4 weeks
We checked Enhance MD's prices on August 28, 2026.
SkinnyRx
A four-product compounded menu with separate injection and dissolving-tablet pages for semaglutide and tirzepatide. Compare the exact formulation, introductory bill and renewal terms; the different routes are not established as clinically equivalent.
- Compounded Semaglutide (injectable)$99Once-weekly injection, quoted at $99 for the first month on its product page. A microdose option is offered.
- Compounded Semaglutide (tablets)$149Oral dissolving tablet, quoted at $149 for the first month. Confirm the exact dispensing directions and later bill; merchant guidance differs on placement.
- Compounded Tirzepatide (injectable)$99Once-weekly tirzepatide injection, a GLP-1 and GIP dual agonist, quoted at $99 for the first month on its product page.
All 4 SkinnyRx plans
- Compounded Tirzepatide (tablets)$199Oral dissolving tablet, quoted at $199 for the first month. Confirm the exact dispensing directions and later bill; this is not an FDA-approved oral tirzepatide product.
How SkinnyRx bills
$99 is a first month rate quoted on the compounded semaglutide and tirzepatide injection product pages. SkinnyRx does not publish a month two price; its terms say the renewal rate is described during checkout.
We checked SkinnyRx's prices on September 26, 2026.
What to watch for with Enhance MD and SkinnyRx
Enhance MD
- The $212 headline is a four-week equivalent on a prepaid 48-week plan, not a calendar-year price. The shortest plan costs $249 every four weeks on the GLP-1 Core pricing page (verified 2026-09-03)
- Compounded only. Every GLP-1 product page states the formulation is not FDA-approved and is compounded under federal Section 503A guidelines, and no brand-name product is sold
Enhance MD's strengths, cautions and terms
Strengths
- Same price at every dose, so titrating up does not raise the monthly bill. GLP-1 Core is $212 per four-week equivalent on the prepaid 48-week plan and $249 every four weeks on the shortest plan (verified 2026-09-03)
- The monthly price covers lab work, the video visit with a provider, medication from a partner pharmacy and 2-day shipping, with no separate consultation fee
- Support is staffed seven days a week, Monday to Friday 8:00 AM to 8:00 PM EDT and Saturday to Sunday 9:00 AM to 5:00 PM EDT, by phone and email
- Four compounded GLP-1 options including a capped 1 mg microdosing tirzepatide plan from $169 per four weeks on the 48-week plan, plus a full refund of the initial payment if a provider finds you ineligible during onboarding
More to watch for
- Not nationwide. The FAQ lists 40 states plus DC and leaves out Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina and Tennessee
- Cash pay with no same-day start: a Quest Diagnostics blood draw and a scheduled video visit both come before a prescription, and no insurance option is shown on the site's pricing, FAQ or terms pages (rendered check 2026-09-03)
- Medicines listed
- Semaglutide (compounded, sold as GLP-1 Core)
- Tirzepatide (compounded, sold as GLP-1 Advanced)
- Semaglutide and tirzepatide in one formulation (compounded, sold as GLP-1 Elite)
- Tirzepatide, 1mg microdosing plan (compounded)
- NAD+ injections (separate anti-aging product, not a GLP-1)
- NAD+ wafers (separate anti-aging product, not a GLP-1)
- Insurance
- No insurance support listed
- Consultation
- Included
- Shipping
- Free
- States
- 40 states plus DC: AK, AZ, CA, CO, CT, DC, DE, FL, IA, ID, IL, IN, KS, KY, MA, MD, ME, MI, MN, MT, NC, NE, NH, NJ, NM, NV, NY, OH, OK, OR, PA, RI, SD, TX, UT, VA, VT, WA, WI, WV, WY. Not available in AL, AR, GA, HI, LA, MO, MS, ND, SC, TN. The FAQ says the company is licensed in all 50 states but that it is launching in the listed states only (verified 2026-09-03)
- Cancellation
- The FAQ says you can pause or cancel your subscription at any time by contacting support, and that membership otherwise renews every 28 days. The 3, 6 and 12-month plans bill every 12, 24 and 48 weeks rather than monthly. Prescription products cannot be returned, and the only refund promised is 100% of the initial payment if a provider finds you ineligible during onboarding (verified 2026-09-03)
SkinnyRx
- Every advertised price is a first month rate and SkinnyRx does not publish what month two costs. Its terms say the renewal rate is described at checkout, and that discounts may be reversed if you cancel before the end of a promotional or committed term.
- SkinnyRx names its medical director, Sajad Zalzala, M.D., and names AyaRx as the telemedicine partner behind its medical services, but it does not name the compounding pharmacy that fills prescriptions and it publishes no founders or executive team.
SkinnyRx's strengths, cautions and terms
Strengths
- Four product-specific options to discuss with a clinician: semaglutide or tirzepatide, each as an injection or a dissolving tablet
- $99 for the first month on both the compounded semaglutide and the compounded tirzepatide injection, quoted on each product page, among the lowest entry rates in the compounded segment
- Fast onboarding: a short online intake, a prescription within 24 hours where no video visit is required, and free overnight shipping on all orders with tracking within 2 business days
- A public Trustpilot profile provides service feedback to read alongside the FDA record and the written billing terms; those reviews do not establish tablet effectiveness
More to watch for
- Cash-pay only, does not bill commercial insurance, Medicare, or Medicaid. HSA/FSA payments are accepted, which is the main way to soften the cost.
- Independent reviews flag inconsistent customer-service responsiveness, a real consideration since titration support and dose adjustments run through chat
- FDA warning letter #717989, issued February 20, 2026 to Lean Rx, Inc. dba SkinnyRx, cites misleading labels and website claims for compounded GLP-1s. It is a labeling/marketing record, not an unsafe-medication finding
- Medicines listed
- Semaglutide (compounded, injectable)
- Wegovy Pill (brand-name oral semaglutide, badged FDA-approved on its product page but shown as Unavailable and offered via SkinnyRx Membership, no price published, verified 2026-09-03)
- Foundayo Pill (brand-name orforglipron, badged FDA-approved on its product page but shown as Unavailable and offered via SkinnyRx Membership, no price published, verified 2026-09-03)
- Semaglutide (compounded, oral dissolving tablets; confirm placement with the dispensing pharmacy)
- Tirzepatide (compounded, injectable)
- Tirzepatide (compounded, oral dissolving tablets; confirm placement with the dispensing pharmacy)
- Insurance
- No insurance support listed
- Consultation
- Included
- Shipping
- Free (overnight on all orders)
- States
- 47 for compounded medications (its terms exclude Alabama, Louisiana and Mississippi and bar residents of those states from ordering them); branded offerings may be available in all states
- Cancellation
- The September 22 terms allow renewal processing up to five days before the next period and require cancellation at least five days before the applicable renewal-processing date. They include non-refundable fees, return-before-refund conditions and possible reversal of promotional discounts. Product FAQs use simpler cancellation/refund wording. Ask support for the exact deadline, refund eligibility and any return requirement in writing before paying; canceling is not a guaranteed refund.
Compounded medicines are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality before they are sold. Read the FDA's explanation of the risks.
Enhance MD vs SkinnyRx: common questions
Is Enhance MD or SkinnyRx cheaper?
At least one headline price is a starting, introductory, prepaid or partial figure, so neither is simply cheaper.
- Enhance MD$212/4 weeks equivalentprepaid 48-week plan; confirm the full upfront charge
- SkinnyRx$99first month, ask the renewal price
Which is better, Enhance MD or SkinnyRx?
Neither wins outright on our scores, so the better one is the one that fits your medicine, budget and care needs.
Enhance MD lists compounded medication only, and SkinnyRx lists brand-name and compounded medication.
Do Enhance MD and SkinnyRx offer brand-name medication?
Enhance MD lists compounded medication only, and SkinnyRx lists brand-name and compounded medication.
Compounded medications are not FDA-approved. Your prescriber decides which medicine suits you.
Do Enhance MD and SkinnyRx take insurance?
Neither Enhance MD nor SkinnyRx lists insurance support.
Where these facts come from
Enhance MD:prices checked August 28, 2026, score evidence assessed October 16, 2026.Read our Enhance MD review
SkinnyRx:prices checked September 26, 2026, score evidence assessed October 16, 2026.Read our SkinnyRx review
We score on a published methodology, and partnership never changes a score or a fact here.
What should you compare next?
- Compare Wegovy pill prices and accessUse the dedicated guide for dose-specific costs, required memberships and which providers currently list the FDA-approved pill.
- Compare complete recurring program costsSee which prices include medication, clinical care and shipping, and which headline amounts require another fee or commitment.
- Compare semaglutide providers and pricesMove from this head-to-head to the broader semaglutide market without confusing compounded products with FDA-approved brands.
Before you sign up, read our trust checks: is Enhance MD legit and is SkinnyRx legit.
Enhance MD reviewSkinnyRx reviewAll comparisonsFind your match