Enhance MD vs Willow: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

48 providers verified independently·Independent research·How we rank →

Willow beats Enhance MD overall, scoring 8.2/10 vs 7.8/10. Enhance MD is more affordable at $212/mo vs $299/mo. Choose Enhance MD for budget-conscious users interested in combination therapies. Choose Willow for users who want comprehensive clinical support with flexibili.

A side-by-side comparison of Enhance MD and Willow covering pricing, scores, medication types, insurance, and more to help you decide.

Enhance MD

#18 of 48

7.8/10

Affordable telehealth provider offering both compounded and brand-name GLP-1 medications with combination therapy options.

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Higher Rated

Willow

#8 of 48

8.2/10

Personalized GLP-1 weight loss with ongoing clinical support. Compounded semaglutide and tirzepatide only — Willow explicitly does not prescribe brand-name Wegovy or Zepbound. Added oral compounded semaglutide tablets as a non-injectable option.

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Feature	Enhance MD	Willow
Our Score	7.8/10	8.2/10
Starting Price	$212/mo	$299/mo
Medication Type	Both	Compounded
Insurance Accepted	No	No
Best For	Budget-conscious users interested in combination therapies	Users who want comprehensive clinical support with flexibility between injectable and oral compounded semaglutide routes
Ranking	#18	#8

Pros & Cons Compared

Enhance MD

Pros

+$115/mo starting price with access to both brand-name and compounded — rare at this price point
+Offers combination therapies (GLP-1 + B12, GLP-1 + NAD+) for patients wanting enhanced protocols
+Quick asynchronous consultations — most patients approved within 24 hours without video calls
+Flexible dosing: can start at lower doses than standard protocols for sensitive patients

Cons

−Lighter clinical support than higher-priced platforms — check-ins are patient-initiated, not scheduled
−No insurance billing and limited customer support hours (business days only, no weekends)

Willow

Pros

+Includes monthly provider check-ins and dose adjustments at no extra cost
+Offers both injectable AND oral compounded semaglutide — one of few platforms with a daily oral tablet option
+$299/mo all-in for compounded semaglutide with monthly provider support
+90%+ patient retention rate after 3 months per their published outcomes data

Cons

−Compounded-only — no brand-name Wegovy or Zepbound through the platform
−Tirzepatide pricing reaches $499-$524 at higher doses — starting dose is $399/mo
−Cash-pay only — no insurance billing, though they provide superbills for FSA/HSA
−Founded in 2024 — less track record than Ro or Hims, though growth has been fast

Our Verdict

Willow edges out Enhance MD with a score of 8.2/10 vs 7.8/10. If budget is your priority, Enhance MD starts at $212/mo compared to Willow's $299/mo. Enhance MD offers both brand-name and compounded medications, giving you more flexibility. Choose Enhance MD if you want: budget-conscious users interested in combination therapies. Choose Willow if you want: users who want comprehensive clinical support with flexibility between injectable and oral compounded semaglutide routes.

Still undecided? Editor's #1 Overall Pick

Eden Health GLP-1

$249/mo · 8.9/10 · Both

If neither Enhance MD nor Willow feels like the right fit, our overall #1 pick across all 48 GLP-1 telehealth providers is Eden Health GLP-1 — strongest balance of clinical oversight, transparent pricing, and verified availability.

Visit Eden Health GLP-1→Read our full Eden Health GLP-1 review