Enhance MD vs Willow: Which GLP-1 Provider Is Better?
Short answer: Enhance MD scores higher on our rubric, 7.8/10 against 7.5/10. Full reasoning, pricing and the cases where the other one wins are below.
Enhance MD beats Willow overall, scoring 7.8/10 vs 7.5/10. Published pricing is not a like-for-like monthly comparison: Enhance MD is from $212/mo; Willow is $299 first month, then $499/mo. Choose Enhance MD for cash-pay shoppers who want the monthly price to stay flat as the dose goes up, and who will do a lab draw and a video visit to get it. Choose Willow for users who want comprehensive clinical support with a needle-free daily tablet option on both semaglutide and tirzepatide.
A side-by-side look at Enhance MD and Willow to help you decide. We compare them on:
- •Starting price per month
- •Our overall score, out of 10
- •Medication type, brand-name or compounded
- •Whether they accept insurance
- •Who each one is best for
Enhance MD
#12 of 54Cash-pay telehealth program selling compounded semaglutide, compounded tirzepatide, a formulation containing both, and a low-dose microdosing tirzepatide plan. Every GLP-1 it sells is compounded and not FDA-approved; there is no brand-name option. The price is flat at every dose, $212/mo on the 12-month plan and $249/mo month to month (verified 2026-09-03).
Visit Enhance MDWillow
#17 of 54Personalized GLP-1 weight loss with ongoing clinical support. The catalogue is compounded semaglutide, compounded tirzepatide and a compounded combination tablet carrying both, with no brand-name Wegovy or Zepbound page anywhere on the site. Daily oral dissolving tablets exist for BOTH molecules alongside the injectables, level with the corresponding injection at the starting doses. Willow serves 36 states, not all 50.
Visit Willow| Feature | Enhance MD | Willow |
|---|---|---|
| Why each one | The most affordable platform offering both medication types plus unique combination therapies (GLP-1 + B12, GLP-1 + NAD+) that no other major provider offers at this price. | The only compounded platform on our index with daily dissolving tablets for BOTH semaglutide and tirzepatide at the injection's starting price, plus a combination tablet carrying the two molecules together, the widest needle-free menu in the compounded category. |
| Our Score | 7.8/10 | 7.5/10 |
| Headline Price | from $212/mo | $299 first month, then $499/mo |
| Medication Type | Compounded | Compounded |
| Insurance Accepted | No | No |
| Best For | Cash-pay shoppers who want the monthly price to stay flat as the dose goes up, and who will do a lab draw and a video visit to get it | Users who want comprehensive clinical support with a needle-free daily tablet option on both semaglutide and tirzepatide |
| Watch out for | The $212/mo headline is the 12-month plan, billed every 48 weeks. Paying month to month costs $249/mo on the GLP-1 Core pricing page (verified 2026-09-03) | Compounded-only, no brand-name Wegovy or Zepbound through the platform |
| Ranking | #12 | #17 |
| Get started | Visit Enhance MD | Visit Willow |
Pros & Cons Compared
Enhance MD
Pros
- +Same price at every dose, so titrating up does not raise the monthly bill. GLP-1 Core is $212/mo on the 12-month plan and $249/mo month to month (verified 2026-09-03)
- +The monthly price covers lab work, the video visit with a provider, medication from a partner pharmacy and 2-day shipping, with no separate consultation fee
- +Support is staffed seven days a week, Monday to Friday 8:00 AM to 8:00 PM EDT and Saturday to Sunday 9:00 AM to 5:00 PM EDT, by phone and email
- +Four compounded GLP-1 options including a capped 1mg microdosing tirzepatide plan at $169/mo, plus a full refund of the initial payment if a provider finds you ineligible during onboarding
Cons
- −The $212/mo headline is the 12-month plan, billed every 48 weeks. Paying month to month costs $249/mo on the GLP-1 Core pricing page (verified 2026-09-03)
- −Compounded only. Every GLP-1 product page states the formulation is not FDA-approved and is compounded under federal Section 503A guidelines, and no brand-name product is sold
- −Not nationwide. The FAQ lists 40 states plus DC and leaves out Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina and Tennessee
- −Cash pay with no same-day start: a Quest Diagnostics blood draw and a scheduled video visit both come before a prescription, and no insurance option is shown on the site's pricing, FAQ or terms pages (rendered check 2026-09-03)
Willow
Pros
- +Includes monthly provider check-ins and dose adjustments at no extra cost
- +Daily oral tablets for BOTH semaglutide and tirzepatide, one of the only platforms with a needle-free route on both molecules
- +$299/mo covers compounded semaglutide at the starting doses, injectable or tablet, with monthly provider support and no separate consultation fee
- +A US licensed doctor reviews and confirms the prescription the same day, and two-day shipping is free, both stated on the product pages (verified 2026-09-03)
Cons
- −Compounded-only, no brand-name Wegovy or Zepbound through the platform
- −Both headline prices are floors. Tirzepatide starts at $399/mo against $299 for semaglutide, and on the help center pricing article maintenance tirzepatide injections run $499/mo from 8.5 mg, $524/mo at 13.5 mg and $549/mo at 17 mg (checked 2026-09-03)
- −Cash-pay only. Willow does not bill insurance. You pay with an HSA or FSA card at checkout, or pay out of pocket and submit receipts to your insurer yourself, with reimbursement depending on your plan and deductible (checked 2026-09-03)
- −The program auto-renews, and a cancellation has to reach the care team at least two business days before the next processing date to stop a charge. A full refund only applies if you cancel before the prescription goes to the pharmacy, and the informed consent page says orders cannot be cancelled, returned or refunded once shipped (checked 2026-09-03)
Our Verdict
Enhance MD edges out Willow with a score of 7.8/10 vs 7.5/10. Published pricing is not a like-for-like monthly comparison: Enhance MD is from $212/mo; Willow is $299 first month, then $499/mo.
Cheapest complete recurring price in our index
Eden Health GLP-1
$99/mo month-to-month, from $34 on a plan · 6.9/10 · Both
Both Enhance MD and Willow start above the cheapest complete recurring program we track. Across all 54 providers in our index, the lowest price with affirmative medication, consultation, and shipping inclusion is Eden Health GLP-1 at $99/mo, price checked August 28, 2026. It scores 6.9/10 and is not the highest-scored provider in our full rankings, so this is a cost floor rather than a recommendation. Worth knowing before you decide.
Read Full Reviews
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Our pick of these two: Enhance MD · 7.8/10