HealthRX vs TMates: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher

Reviewed & updated September 3, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

54 providers verified independently·Independent research·How we rank →

Short answer: TMates scores higher on our rubric, 7.8/10 against 5.2/10. Full reasoning, pricing and the cases where the other one wins are below.

Visit TMates - our pick of these two →or find your match

TMates beats HealthRX overall, scoring 7.8/10 vs 5.2/10. Published pricing is not a like-for-like monthly comparison: HealthRX is from $99/mo; TMates is from $158/mo. Choose HealthRX for cash-pay patients who want low flat-dose compounded glp-1 pricing, all-50-state access, fast shipping, and self-service cancellation. Choose TMates for users who want commitment-discount pricing on compounded glp-1s (semaglutide $158-$249/mo, tirzepatide $167-$297/mo, medication included) or a $99/mo clinical path to brand wegovy or zepbound filled at their own pharmacy.

A side-by-side look at HealthRX and TMates to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

HealthRX

#47 of 54

5.2/10

HealthRX is a cash-pay telehealth platform for compounded injectable semaglutide and tirzepatide. Its pricing page publishes eight plans: semaglutide at $190 month to month, $133/mo on 3 months, $119/mo on 6 months and $99/mo on 12 months, and tirzepatide at $239, $209, $199 and $179 on the same terms. Prices stay flat across doses and include clinician review, dose adjustments and overnight shipping, and the site promises a full refund if a provider does not approve you. Prescriptions come from independent US-licensed clinicians, and neither a clinician network nor the dispensing 503A pharmacy is named on the site's about, how it works, FAQ or terms pages (rendered check 2026-09-03).

Visit HealthRX

Higher Rated

TMates

#10 of 54

7.8/10

Telemedicine platform offering two distinct archetypes: compounded semaglutide and tirzepatide with medication included (semaglutide $158-$249/mo, tirzepatide $167-$297/mo on commitment pricing), and a clinical-service-only path to brand-name Wegovy/Zepbound at $99/mo where the prescription is sent to the patient's pharmacy. Phentermine also available. 2026 expansion added brand-name FDA-approved options.

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Feature	HealthRX	TMates
Why each one	Low flat-dose pricing paired with linked LegitScript verification, nationwide clinician coverage, overnight shipping, and self-service account cancellation.	Two-archetype platform: (1) compounded GLP-1s with medication included and steep multi-month commitment discounts; (2) cheap $99/mo clinical service for brand Wegovy/Zepbound where you fill the prescription at your own pharmacy.
Our Score	5.2/10	7.8/10
Headline Price	from $99/mo	from $158/mo
Medication Type	Compounded	Both
Insurance Accepted	No	Yes
Best For	Cash-pay patients who want low flat-dose compounded GLP-1 pricing, all-50-state access, fast shipping, and self-service cancellation	Users who want commitment-discount pricing on compounded GLP-1s (semaglutide $158-$249/mo, tirzepatide $167-$297/mo, medication included) or a $99/mo clinical path to brand Wegovy or Zepbound filled at their own pharmacy
Watch out for	The dispensing 503A pharmacy is described by type while its name and license remain absent from the public site	The $99/mo Wegovy or Zepbound tier buys the prescription and provider oversight only. TMates says it does not dispense or ship the drug, and no price for the medication itself appears on its product or category pages, so your own pharmacy bills you separately (checked 2026-09-03).
Ranking	#47	#10
Get started	Visit HealthRX	Visit TMates

Pros & Cons Compared

HealthRX

Pros

+$99/mo compounded semaglutide on the 12-month plan, with a $133/mo 3-month option
+Flat pricing across doses, clinician review, dose adjustments, and overnight shipping included
+Independent US-licensed clinicians in all 50 states, with the homepage saying a board-certified physician reviews your file within 24 hours
+Full refund if a provider does not approve you, stated on the homepage, the pricing page and the terms
+LegitScript certificate 50087439 links to the issuer's verification checker
+Single-click account cancellation and refunds for unshipped doses
+Published HIPAA notice, telehealth consent, safety information, and emergency instructions

Cons

−The dispensing 503A pharmacy is described by type while its name and license remain absent from the public site
−Legal entity, headquarters, executive team, and medical director remain undisclosed
−The $99/mo semaglutide headline needs $1,188 paid up front for a full year. Buying month to month costs $190 on its pricing page, verified 2026-09-03
−The 4.8/5 from 12,000+ members block uses illustrative composites rather than an independent review platform
−Cash-pay only, with no insurance billing or prior-authorization support
−Compounded medications sit outside FDA premarket approval as finished products

TMates

Pros

+Clinical-service-only path to brand Wegovy and Zepbound at $99/mo, prescription goes to patient's pharmacy (you fill separately using insurance or cash)
+Steep multi-month commitment discounts on compounded sema, $158/mo on 12-month plan ($1,900 upfront) vs $249/mo month-to-month
+Same price at all dose levels for compounded, no cost escalation as you titrate up
+Phentermine available at $149/mo for patients who benefit from a different appetite-suppressant approach

Cons

−The $99/mo Wegovy or Zepbound tier buys the prescription and provider oversight only. TMates says it does not dispense or ship the drug, and no price for the medication itself appears on its product or category pages, so your own pharmacy bills you separately (checked 2026-09-03).
−The best compounded rates require prepayment: $1,050 upfront for 6 months, $1,900 for 12. Start at $249 month-to-month if you want to test fit first.
−The intake is a 90-second quiz. Fast, but lighter screening than competitors with full medical intakes. Better suited to patients who already know GLP-1 basics.
−TMates prescribes brand-name but does not dispense it, and is not affiliated with Novo Nordisk (Wegovy) or Eli Lilly (Zepbound). Your own pharmacy fills the Rx.

Our Verdict

TMates edges out HealthRX with a score of 7.8/10 vs 5.2/10. Published pricing is not a like-for-like monthly comparison: HealthRX is from $99/mo; TMates is from $158/mo. TMates accepts insurance, which can significantly reduce your out-of-pocket costs. TMates offers both brand-name and compounded medications, giving you more flexibility.