Hume Care vs SkinnyRx: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher

Reviewed & updated September 15, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

36 providers verified independently·Independent research·How we rank →

Short answer: SkinnyRx scores higher on our rubric, 5.3/10 against 3.8/10. Full reasoning, pricing and the cases where the other one wins are below.

Visit SkinnyRx - our pick of these two →or find your match

SkinnyRx beats Hume Care overall, scoring 5.3/10 vs 3.8/10. Published pricing is not a like-for-like monthly comparison: Hume Care is from $199/mo; SkinnyRx is $99 first month, rises after. Choose Hume Care for readers comparing a self-pay glp-1 program with connected app and body-composition tracking. Choose SkinnyRx for users who want a choice of compounded glp-1 format, a weekly injection or a daily tablet taken under the tongue, at a low first month price.

A side-by-side look at Hume Care and SkinnyRx to help you decide. We compare them on:

•Starting price and billing period
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

Hume Care

#35 of 36

3.8/10

Hume Care is a prescribing-access program operated by Hume Health Care LLC, distinct from Hume’s device-only products. Its GLP-1Rx page advertises $199 monthly with medication if prescribed and care. The terms identify an independent clinical network and link to MDIntegrations. Specific pharmacy, dose-level prices and consistent clinical-leadership details remain unverified.

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Higher Rated

SkinnyRx

#28 of 36

5.3/10

Direct-to-consumer telehealth platform operated by Lean Rx, Inc. (Sacramento, CA). Its Treatments menu carries four compounded GLP-1 formats, semaglutide and tirzepatide each as a once-weekly injection or a once-daily tablet taken under the tongue, plus two brand-name oral pills, the Wegovy Pill and the Foundayo Pill, both badged FDA-approved and both shown as Unavailable and offered through a SkinnyRx Membership. Every advertised price is a first month rate. Compounded medications are not sold in Alabama, Louisiana or Mississippi. Cash-pay only with HSA/FSA accepted; does not bill insurance. 4,100+ Trustpilot reviews at 4.8 stars.

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Feature	Hume Care	SkinnyRx
Our Score	3.8/10	5.3/10
Headline Price	from $199/mo	$99 first month, rises after
Medication Type	Compounded	Both
Insurance Accepted	Self-pay only under the current terms; not a Medicare or insurance coverage route.	No
Best For	Readers comparing a self-pay GLP-1 program with connected app and body-composition tracking	Users who want a choice of compounded GLP-1 format, a weekly injection or a daily tablet taken under the tongue, at a low first month price
Watch out for	No verified dispensing pharmacy in the sources reviewed	Every advertised price is a first month rate and SkinnyRx does not publish what month two costs. Its terms say the renewal rate is described at checkout, and that discounts may be reversed if you cancel before the end of a promotional or committed term.
Ranking	#35	#28
Get started	Visit Hume Care	Visit SkinnyRx

Pros & Cons Compared

Hume Care

Pros

+Published $199 monthly GLP-1Rx offer with care and medication if prescribed
+Connected app for logging and program support
+Independent clinical network and legal entity identified in terms

Cons

−No verified dispensing pharmacy in the sources reviewed
−Oral formulation and dose-specific prices are not sufficiently clear to compare
−Clinical-leadership details differ across public pages
−Independent treatment outcomes and customer-review totals have not been established

SkinnyRx

Pros

+Four compounded formats, both molecules as both a weekly injection and a daily tablet taken under the tongue, including the tirzepatide tablet that almost no competitor offers
+$99 for the first month on both the compounded semaglutide and the compounded tirzepatide injection, quoted on each product page, among the lowest entry rates in the compounded segment
+Fast onboarding: a short online intake, a prescription within 24 hours where no video visit is required, and free overnight shipping on all orders with tracking within 2 business days
+4,100+ Trustpilot reviews at 4.8 stars, among the strongest aggregate social-proof signals in the GLP-1 telehealth category

Cons

−Every advertised price is a first month rate and SkinnyRx does not publish what month two costs. Its terms say the renewal rate is described at checkout, and that discounts may be reversed if you cancel before the end of a promotional or committed term.
−SkinnyRx names its medical director, Sajad Zalzala, M.D., and names AyaRx as the telemedicine partner behind its medical services, but it does not name the compounding pharmacy that fills prescriptions and it publishes no founders or executive team.
−Cash-pay only, does not bill commercial insurance, Medicare, or Medicaid. HSA/FSA payments are accepted, which is the main way to soften the cost.
−Independent reviews flag inconsistent customer-service responsiveness, a real consideration since titration support and dose adjustments run through chat
−FDA warning letter #717989, issued February 20, 2026 to Lean Rx, Inc. dba SkinnyRx, cites misleading labels and website claims for compounded GLP-1s. It is a labeling/marketing record, not an unsafe-medication finding

Our Verdict

SkinnyRx edges out Hume Care with a score of 5.3/10 vs 3.8/10. Published pricing is not a like-for-like monthly comparison: Hume Care is from $199/mo; SkinnyRx is $99 first month, rises after. SkinnyRx offers both brand-name and compounded medications, giving you more flexibility.