First month, ask the renewal price · checked Sep 26
Check price for SkinnyRxOn SkinnyRx's site · partner link
Comparison · updated October 16, 2026
SkinnyRx vs SynergyRx: Costs, care and treatment fit
SkinnyRx and SynergyRx differ in what you pay and which medicines they list. Compounded medicines are not FDA-approved.
Confirm the billing interval and additional fees
See prices and terms for SynergyRxThese two prices are different kinds of bill, so read the line under each price before you compare them.
SkinnyRx pays us a commission when you join through our links. SynergyRx does not. That never changes a score, an order or a fact on this page. How we make money
Which should you choose, SkinnyRx or SynergyRx?
Short answer: SkinnyRx and SynergyRx differ in what you pay and which medicines they list, so the plans below decide it.
SkinnyRx is best for
Cash-pay readers comparing compounded injections and dissolving tablets with a clinician, after confirming the refill bill and evidence for the exact formulation.
SynergyRx is best for
Needle-phobic users who want oral dissolving tablets for semaglutide or tirzepatide, with 24/7 support included.
The available assessments do not establish a score winner, so choose by the medicine, total cost and care you need.
By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice
SkinnyRx vs SynergyRx side by side
| SkinnyRx | SynergyRx | |
|---|---|---|
| Price | $99First month, ask the renewal price | $199Confirm the billing interval and additional fees |
| Medicine | BothBrand-name and compounded | |
| Needle-free option | BothYes, a pill or other oral form | |
| Insurance | BothNo insurance listed | |
| Consultation | Included | Included in most plans according to the homepage FAQ, not confirmed for every offer |
| Shipping | Free (overnight on all orders) | Free expedited |
| Where it ships | 47 for compounded medications (its terms exclude Alabama, Louisiana and Mississippi and bar residents of those states from ordering them); branded offerings may be available in all states | Availability depends on the patient's state, the service and clinician eligibility under the terms reviewed October 8, 2026; no all-state GLP-1 service list was verified |
| Trustpilot | 4.8 / 5 across 4,100 reviews | Not tracked |
| Our score | 5/10 Mixed | 6.2/10 Fair |
| Assessment limits | Checked Oct 16, 2026; a rating claim didn't match Trustpilot. | Checked Oct 16, 2026; few independent reviews yet. |
What SkinnyRx and SynergyRx plans cost
SkinnyRx
A four-product compounded menu with separate injection and dissolving-tablet pages for semaglutide and tirzepatide. Compare the exact formulation, introductory bill and renewal terms; the different routes are not established as clinically equivalent.
- Compounded Semaglutide (injectable)$99Once-weekly injection, quoted at $99 for the first month on its product page. A microdose option is offered.
- Compounded Semaglutide (tablets)$149Oral dissolving tablet, quoted at $149 for the first month. Confirm the exact dispensing directions and later bill; merchant guidance differs on placement.
- Compounded Tirzepatide (injectable)$99Once-weekly tirzepatide injection, a GLP-1 and GIP dual agonist, quoted at $99 for the first month on its product page.
All 4 SkinnyRx plans
- Compounded Tirzepatide (tablets)$199Oral dissolving tablet, quoted at $199 for the first month. Confirm the exact dispensing directions and later bill; this is not an FDA-approved oral tirzepatide product.
How SkinnyRx bills
$99 is a first month rate quoted on the compounded semaglutide and tirzepatide injection product pages. SkinnyRx does not publish a month two price; its terms say the renewal rate is described during checkout.
We checked SkinnyRx's prices on September 26, 2026.
SynergyRx
Offers oral dissolving tablets for semaglutide and tirzepatide alongside injectable options. Discuss the specific formulation and its supporting evidence with your prescriber rather than assuming the same results across routes.
- Compounded Semaglutide (injection)$199Injectable format, listed as starting at $199 on the products page
- Compounded Semaglutide (oral dissolving tablet)$299Needle-free tablet, listed as starting at $299 on the products page
- Compounded Tirzepatide (injection)$349Injectable format, listed as starting at $349 on the products page
All 6 SynergyRx plans
- Compounded Tirzepatide (oral dissolving tablet)$399Needle-free tablet, listed as starting at $399 on the products page
- Brand-Name Ozempic$499FDA-approved Ozempic with clinical support
- Brand-Name Wegovy/Mounjaro$947FDA-approved brand-name with full clinical support
How SynergyRx bills
Compounded semaglutide injection starts at $199; the oral dissolving tablet starts at $299. Supply duration and billing interval are not publicly confirmed. Most plans include visits and medication, but the full charge depends on the plan, medication and pharmacy. A $100 welcome credit is advertised as applied at checkout with no code needed; confirm how it applies to your offer
We checked SynergyRx's prices on September 3, 2026.
What to watch for with SkinnyRx and SynergyRx
SkinnyRx
- Every advertised price is a first month rate and SkinnyRx does not publish what month two costs. Its terms say the renewal rate is described at checkout, and that discounts may be reversed if you cancel before the end of a promotional or committed term.
- SkinnyRx names its medical director, Sajad Zalzala, M.D., and names AyaRx as the telemedicine partner behind its medical services, but it does not name the compounding pharmacy that fills prescriptions and it publishes no founders or executive team.
SkinnyRx's strengths, cautions and terms
Strengths
- Four product-specific options to discuss with a clinician: semaglutide or tirzepatide, each as an injection or a dissolving tablet
- $99 for the first month on both the compounded semaglutide and the compounded tirzepatide injection, quoted on each product page, among the lowest entry rates in the compounded segment
- Fast onboarding: a short online intake, a prescription within 24 hours where no video visit is required, and free overnight shipping on all orders with tracking within 2 business days
- A public Trustpilot profile provides service feedback to read alongside the FDA record and the written billing terms; those reviews do not establish tablet effectiveness
More to watch for
- Cash-pay only, does not bill commercial insurance, Medicare, or Medicaid. HSA/FSA payments are accepted, which is the main way to soften the cost.
- Independent reviews flag inconsistent customer-service responsiveness, a real consideration since titration support and dose adjustments run through chat
- FDA warning letter #717989, issued February 20, 2026 to Lean Rx, Inc. dba SkinnyRx, cites misleading labels and website claims for compounded GLP-1s. It is a labeling/marketing record, not an unsafe-medication finding
- Medicines listed
- Semaglutide (compounded, injectable)
- Wegovy Pill (brand-name oral semaglutide, badged FDA-approved on its product page but shown as Unavailable and offered via SkinnyRx Membership, no price published, verified 2026-09-03)
- Foundayo Pill (brand-name orforglipron, badged FDA-approved on its product page but shown as Unavailable and offered via SkinnyRx Membership, no price published, verified 2026-09-03)
- Semaglutide (compounded, oral dissolving tablets; confirm placement with the dispensing pharmacy)
- Tirzepatide (compounded, injectable)
- Tirzepatide (compounded, oral dissolving tablets; confirm placement with the dispensing pharmacy)
- Insurance
- No insurance support listed
- Consultation
- Included
- Shipping
- Free (overnight on all orders)
- States
- 47 for compounded medications (its terms exclude Alabama, Louisiana and Mississippi and bar residents of those states from ordering them); branded offerings may be available in all states
- Cancellation
- The September 22 terms allow renewal processing up to five days before the next period and require cancellation at least five days before the applicable renewal-processing date. They include non-refundable fees, return-before-refund conditions and possible reversal of promotional discounts. Product FAQs use simpler cancellation/refund wording. Ask support for the exact deadline, refund eligibility and any return requirement in writing before paying; canceling is not a guaranteed refund.
SynergyRx
- The terms publish a Casper, WY address. The October 8, 2026 source check did not confirm a Trustpilot profile on its exact domain; that does not establish that no profile or reviews exist.
- Recorded brand-name starting prices are $499-947, with supply duration and billing interval unconfirmed. Compare the same medication, dose, eligibility and complete charge with the relevant manufacturer's program; a compounded tablet is not an FDA-approved brand equivalent.
SynergyRx's strengths, cautions and terms
Strengths
- Oral dissolving tablets for BOTH semaglutide AND tirzepatide, one of the few platforms with needle-free tirzepatide
- Free expedited shipping included with all orders
- Advertises 24/7 support with unlimited appointments and messaging
- Both compounded and brand-name options available (Ozempic, Wegovy, Mounjaro)
More to watch for
- Founding date and ownership are not shown on the site's contact, about, terms or FAQ pages (rendered check 2026-09-03); the terms disclose only a Delaware corporation. The terms also name Usable Health, PC as the medical group while the FAQ names Lion MD.
- Medicines listed
- Semaglutide (compounded, injectable and oral dissolving tablet)
- Tirzepatide (compounded, injectable and oral dissolving tablet)
- Ozempic (brand-name)
- Wegovy (brand-name)
- Mounjaro (brand-name)
- Insurance
- No insurance support listed
- Consultation
- Included in most plans according to the homepage FAQ, not confirmed for every offer. The terms allow charges to vary by medication and pharmacy; confirm the consultation fee and full total before paying.
- Shipping
- Free expedited
- States
- Availability depends on the patient's state, the service and clinician eligibility under the terms reviewed October 8, 2026; no all-state GLP-1 service list was verified. Confirm your state before paying.
- Cancellation
- All sales final. The terms say medical consult fees are not eligible for a refund and prescription products cannot be returned, and no cancellation or auto-renewal clause appears in them, yet the about page still shows a Money Back Guarantee badge with no terms attached.
Compounded medicines are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality before they are sold. Read the FDA's explanation of the risks.
SkinnyRx vs SynergyRx: common questions
Is SkinnyRx or SynergyRx cheaper?
At least one headline price is a starting, introductory, prepaid or partial figure, so neither is simply cheaper.
- SkinnyRx$99first month, ask the renewal price
- SynergyRx$199Confirm the billing interval and additional fees
Which is better, SkinnyRx or SynergyRx?
Neither wins outright on our scores, so the better one is the one that fits your medicine, budget and care needs.
Do SkinnyRx and SynergyRx offer brand-name medication?
SkinnyRx and SynergyRx both list brand-name and compounded medication.
Compounded medications are not FDA-approved. Your prescriber decides which medicine suits you.
Do SkinnyRx and SynergyRx take insurance?
Neither SkinnyRx nor SynergyRx lists insurance support.
Where these facts come from
SkinnyRx:prices checked September 26, 2026, score evidence assessed October 16, 2026.Read our SkinnyRx review
SynergyRx:prices checked September 3, 2026, score evidence assessed October 16, 2026.SynergyRx pricing and sources
We score on a published methodology, and partnership never changes a score or a fact here.
What should you compare next?
- Compare Wegovy pill prices and accessUse the dedicated guide for dose-specific costs, required memberships and which providers currently list the FDA-approved pill.
- Compare complete recurring program costsSee which prices include medication, clinical care and shipping, and which headline amounts require another fee or commitment.
- Compare semaglutide providers and pricesMove from this head-to-head to the broader semaglutide market without confusing compounded products with FDA-approved brands.
Before you sign up, read our trust check: is SkinnyRx legit.
SkinnyRx reviewSynergyRx prices and sourcesAll comparisonsFind your match