MangoRx vs Sesame Care: Which GLP-1 Provider Is Better?
By Iacob Pastina, Independent Researcher
Sesame Care beats MangoRx overall, scoring 7.9/10 vs 7.5/10. Sesame Care is more affordable at $99/mo vs $299/mo. Choose MangoRx for needle-phobic users who want oral-only glp-1 tablets from a . Choose Sesame Care for users who want cheap fda-approved brand-name glp-1 access ($.
A side-by-side look at MangoRx and Sesame Care to help you decide. We compare them on:
- •Starting price per month
- •Our overall score, out of 10
- •Medication type, brand-name or compounded
- •Whether they accept insurance
- •Who each one is best for
MangoRx
#26 of 52Multi-service telehealth platform offering compounded GLP-1 alongside other health services.
Visit MangoRxSesame Care
#7 of 52Telehealth marketplace offering both a low-cost consultation model ($25/visit) and the new Success by Sesame membership program ($59/mo on 3/6/12-month plans) that bundles FDA-approved brand-name GLP-1 medications, including Foundayo (orforglipron), Wegovy pen and pill, and Zepbound.
Visit Sesame Care| Feature | MangoRx | Sesame Care |
|---|---|---|
| Our Score | 7.5/10 | 7.9/10 |
| Starting Price | $299/mo | $99/mo |
| Medication Type | Compounded | Both |
| Insurance Accepted | No | Yes |
| Best For | Needle-phobic users who want oral-only GLP-1 tablets from a publicly traded company | Users who want cheap FDA-approved brand-name GLP-1 access ($149-349/mo Wegovy and Zepbound via Success by Sesame), or insured patients who just need a prescriber |
| Ranking | #26 | #7 |
| Get started | Visit MangoRx | Visit Sesame Care |
Pros & Cons Compared
MangoRx
Pros
- +Oral dissolving tablets exclusively, zero injections for any GLP-1 option
- +Publicly traded on NASDAQ (MGRX), SEC-required financial transparency that private competitors can't match
- +Semaglutide tablet includes Vitamin B6 to help reduce nausea during treatment
- +Free 100% online consultation with no video call required
Cons
- −Oral semaglutide at $299/mo runs 2-3x injectable alternatives ($99-149/mo). The premium only makes sense if needles are a hard no for you.
- −Early-stage public company with limited revenue; the same SEC filings that provide transparency also show the financial uncertainty reflected in the stock.
- −Oral tablets are the only format, with no injectable option if you want higher bioavailability. If you may switch to injections later, pick a platform that carries both.
Sesame Care
Pros
- +Success by Sesame program launched 2026, $59/mo on a 3/6/12-month plan, bundles labs, unlimited messaging, and provider choice
- +Brand-name cash pricing is competitive, Wegovy pen $199 intro / $349 ongoing, Zepbound vial $299, Wegovy pill $149
- +Foundayo (Lilly's FDA-approved oral GLP-1) available as of April 2026 at $149/mo
- +Original pay-per-visit model still available at $25/consultation for users who just need a prescriber
Cons
- −Two distinct products (pay-per-visit vs the Success membership) sit side by side, so decide which you're buying before checkout
- −The $59/mo Success by Sesame rate requires a 3-month minimum commitment; month-to-month is available at $99/mo if you don't want to commit
- −Compounded meds are de-emphasized in the current marketing, the platform now leads with FDA-approved brand-name paths
- −A marketplace rather than a concierge, expect less hand-holding than dedicated subscription platforms
Our Verdict
Sesame Care edges out MangoRx with a score of 7.9/10 vs 7.5/10. If budget is your priority, Sesame Care starts at $99/mo compared to MangoRx's $299/mo. Sesame Care accepts insurance, which can significantly reduce your out-of-pocket costs. Sesame Care offers both brand-name and compounded medications, giving you more flexibility. Choose MangoRx if you want: needle-phobic users who want oral-only glp-1 tablets from a publicly traded company. Choose Sesame Care if you want: users who want cheap fda-approved brand-name glp-1 access ($149-349/mo wegovy and zepbound via success by sesame), or insured patients who just need a prescriber.
Still undecided? Editor's Featured Pick
Yucca Health
$146/mo · 7.7/10 · Compounded
If neither MangoRx nor Sesame Care feels like the right fit, our featured pick across all 52 GLP-1 telehealth providers is Yucca Health. It is not the highest-scored provider in our full rankings. We feature it for its low-friction value: a flat $146/mo that stays the same at every dose.
Read Full Reviews
Related comparisons
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- MangoRx vs MyStart Health$299/mo
- MangoRx vs Direct Meds GLP-1$297/mo
- MangoRx vs Breeze Meds$199/mo
- Sesame Care vs Found$129/mo
- Sesame Care vs Hers$199/mo
- Sesame Care vs bmiMD$119/mo
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