Comparison · updated October 16, 2026

MangoRx vs Sesame Care: MangoRx for compounded medication, Sesame Care for brand-name medication

MangoRx and Sesame Care differ in what you pay, which medicines they list and their insurance terms. Compounded medicines are not FDA-approved.

These two prices are different kinds of bill, so read the line under each price before you compare them.

Compare plans and terms

MangoRx and Sesame Care pay us a commission when you join through our links. That never changes a score, an order or a fact on this page. How we make money

Which should you choose, MangoRx or Sesame Care?

Short answer: Choose MangoRx if you want a compounded medicine and accept that it is not FDA-approved. Choose Sesame Care if you want brand-name medicine rather than a compounded version.

Choose MangoRx if

  • you want a compounded medicine and accept that it is not FDA-approved

Choose Sesame Care if

  • you want brand-name medicine rather than a compounded version
  • you want to use insurance

The available assessments do not establish a score winner, so choose by the medicine, total cost and care you need.

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

MangoRx vs Sesame Care side by side

MangoRx and Sesame Care compared fact by fact
MangoRxSesame Care
Price$299Slim tablets; confirm billing interval, shipping and consultation fees$99/moProgram fee + medication; confirm monthly vs 28-day billing
MedicineCompounded onlyBrand-name only
Needle-free optionBothYes, a pill or other oral form
InsuranceNo insurance listedAccepts insurance
ConsultationFree when the visit ends in a prescriptionVisits start at $34 on the homepage, with some services listed from $36; visits are included in the Success by Sesame subscription
ShippingPublished sources conflict: the homepage advertises free shipping on all orders, while the FAQ ties free shipping to Subscribe and SaveNot published
Where it ships46 states plus Washington D.C. The FAQ shipping list leaves out Alabama, Alaska, Arkansas and Mississippi, and there is no separate state list for the Slim weight loss tabletAll 50 states
Trustpilot4.4 / 5 across 18 reviews4.6 / 5 across 4,533 reviews
BBB ratingNot trackedA+
Our score2.4/10 Limited6.7/10 Fair
Assessment limitsChecked Oct 16, 2026; few independent reviews yet.Checked Oct 16, 2026; a rating claim didn't match Trustpilot.

What MangoRx and Sesame Care plans cost

MangoRx

Slim is a compounded oral dissolving semaglutide tablet with Vitamin B6, rather than an injection.

  • Slim oral semaglutide tablets$299Advertised product price. Monthly delivery is described, but the general subscription FAQ says auto-refills process every 25 days. Confirm Slim's charge schedule, shipping, any consultation fees and the full bill.
How MangoRx bills

Slim advertises $299 on its product page, checked October 10, 2026. Monthly delivery does not establish the billing interval: the general Subscribe and Save FAQ says auto-refills process every 25 days. Confirm the selected Slim supply, charge schedule and full total.

We checked MangoRx's prices on October 10, 2026.

Sesame Care

Provider choice, ongoing video care and medication prior-authorization help, with a separately priced brand-name GLP-1 menu and $59/mo advertised care on an annual commitment.

  • Success by Sesame (12-month plan)$59The $59/mo headline rate. The program page footnote reads "Based on a 12-month Success by Sesame commitment". Bundles provider visits, unlimited messaging and provider choice. Medication is separate.
  • Success by Sesame (6-month plan)$69Billed once every 6 months. The FAQ publishes this as a saving of $180 every 6 months against the $99 monthly rate, which works out near $69/mo. Medication is separate.
  • Success by Sesame (3-month plan)$79Billed once every 3 months. The FAQ publishes this as a saving of $60 every 3 months against the $99 monthly rate, which works out near $79/mo. Medication is separate.
All 9 Sesame Care plans
  • Success by Sesame (month-to-month)$99$99 program fee with no commitment; medication is separate. One program FAQ says billed every month, while another says every 28 days. Confirm the billing interval, your next payment date and how many charges you will pay in a year.
  • Single Consultation (pay-per-visit)$34One-off telehealth visit, no subscription required. The homepage says visits start at $34 and lists some services from $36.
  • Wegovy Pen (brand-name cash)$199Medication only: $199/month for the first two consecutive months at 0.25 or 0.5 mg for eligible new self-pay patients through December 31, 2026, then $349 for listed 0.25–2.4 mg doses. Care fees are separate
  • Wegovy Pill (oral semaglutide)$149Sesame lists $149/mo at 1.5 or 4 mg and $299 at 9 or 25 mg. Medication only; confirm current offer eligibility and add the separate care fee
  • Zepbound KwikPen (brand-name cash)$299The detailed menu lists $299 at 2.5 mg, $398 at 5 mg, $499 at 7.5 mg and $698 at 10–15 mg. A separate vial teaser also says from $299. Confirm the prescribed format and applicable manufacturer offer; care fees are separate
  • Foundayo (orforglipron oral)$149Medication only. Through December 31, 2026, Sesame's offer FAQ lists $149 at 0.8/2.5 mg, $199 at 5.5 mg and $299 at 9 mg. At 14.5/17.2 mg it lists $349, or $299 with Journey Program terms and refills within 45 days. The medication card shows higher non-promotional figures at some doses; confirm the applicable offer and add care fees
How Sesame Care bills

Program fee only. Medication is extra, so confirm the full bill. The program page says monthly in one FAQ and every 28 days in another. Confirm the billing interval and combined bill before paying.

We checked Sesame Care's prices on October 9, 2026.

What to watch for with MangoRx and Sesame Care

MangoRx

  • The current Slim amount does not identify its billing interval or full cost. Get the written supply, renewal and fee terms before comparing it with a monthly plan.
  • Company-wide reviews are a small sample and do not establish results for the Slim tablet.
MangoRx's strengths, cautions and terms

Strengths

  • Oral dissolving tablets exclusively, zero injections for any GLP-1 option
  • Mangoceuticals, Inc. publishes corporate information; company disclosure is separate from clinical quality
  • Slim lists compounded semaglutide with Vitamin B6; an ingredient listing does not establish a nausea benefit
  • Intake is 100% online with no insurance needed, and the provider visit costs nothing when it ends in a prescription

More to watch for

  • The verified GLP-1 menu is oral-only. A compounded tablet is not interchangeable with an FDA-approved product, and injection results do not establish its effectiveness.
Medicines listed
  • Semaglutide 1 to 6 mg compounded with Vitamin B6 into a mint-flavored oral dissolving tablet, sold as Slim and the only weight loss product in the catalogue (verified 2026-09-03)
Insurance
No insurance support listed
Consultation
Free when the visit ends in a prescription. The refund policy charges $80 for a video consult or $70 for a phone consult if GLP-1s are judged not a good fit after the appointment, and $80 for a cancellation inside 24 hours or a no-show (verified 2026-09-03)
Shipping
Published sources conflict: the homepage advertises free shipping on all orders, while the FAQ ties free shipping to Subscribe and Save. Confirm the shipping charge for the selected Slim plan (checked October 8, 2026).
States
46 states plus Washington D.C. The FAQ shipping list leaves out Alabama, Alaska, Arkansas and Mississippi, and there is no separate state list for the Slim weight loss tablet (verified 2026-09-03)
Cancellation
Published on the refund policy page: cancel or reschedule at least 24 hours ahead or pay an $80 fee, no-shows are also $80, refund requests must be made within 30 days, and the terms state all sales are final with auto-refills cancellable up to 48 hours before renewal (verified 2026-09-03)

Sesame Care

  • Sesame runs three separate routes under one brand: the Success by Sesame weight loss subscription, EverydayRx for diabetes, and one-off visits from $34. Check which one you are signing up for before you pay.
  • The $59/mo Success by Sesame rate applies only on a 12-month commitment. The 3-month plan works out near $79/mo and the 6-month near $69/mo from the savings the FAQ publishes. For the $99 no-commitment plan, one FAQ says monthly and another says every 28 days. Confirm the interval and number of charges before budgeting for a year.
Sesame Care's strengths, cautions and terms

Strengths

  • Success by Sesame is $59/mo on the 12-month commitment and includes provider visits, unlimited messaging and provider choice; lab work is covered only at Quest Diagnostics and not in AZ, HI, ND, NJ, NY, OK, RI, SD or WY, where lab fees are extra; medication is separate
  • Published medication-only offers include eligible Wegovy pen starter doses at $199 for two months, then $349; the Wegovy pill and Zepbound KwikPen have dose-specific prices
  • Listed oral brands include Wegovy and Foundayo, with medication starting at $149 for eligible doses; the care fee is separate
  • Provider choice, ongoing video visits, messaging and app tools for weight, dose and side-effect tracking are described in the program

More to watch for

  • Sesame says compounded semaglutide is not currently available. Its published GLP-1 menu is brand-name; medication is billed on top of the program or visit fee.
  • Providers can set higher fees than the advertised program rate. Confirm the selected clinician's price and support arrangements before enrolling
Medicines listed
  • Wegovy (brand-name injection pen)
  • Wegovy (brand-name oral pill)
  • Ozempic (brand-name injection)
  • Zepbound (brand-name KwikPen/vial)
  • Mounjaro (brand-name injection)
  • Rybelsus (brand-name oral)
  • Foundayo (brand-name orforglipron oral, FDA-approved April 2026)
Insurance
Lists insurance support. Confirm coverage for your plan.
Consultation
Visits start at $34 on the homepage, with some services listed from $36; visits are included in the Success by Sesame subscription (verified 2026-09-03)
Shipping
Not published. A shipping cost is not shown on the site's weight loss program, medication or FAQ pages (rendered check 2026-09-03). Prescriptions are picked up at a local pharmacy or sent by home delivery, so any delivery charge comes from the pharmacy
States
All
Cancellation
You can self-cancel Success by Sesame at any time, and cancellation must happen before the next billing cycle starts to avoid the next charge. A full refund applies only if you cancel at least 3 hours before the initial visit, no refund is issued for the first month once that visit has happened, and fees for previous months are not refundable (verified 2026-09-03)

Compounded medicines are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality before they are sold. Read the FDA's explanation of the risks.

MangoRx vs Sesame Care: common questions

Is MangoRx or Sesame Care cheaper?

At least one headline price is a starting, introductory, prepaid or partial figure, so neither is simply cheaper.

  • MangoRx$299Slim tablets; confirm billing interval, shipping and consultation fees
  • Sesame Care$99/moprogram fee + medication; confirm monthly vs 28-day billing

Which is better, MangoRx or Sesame Care?

Neither wins outright on our scores, so the better one is the one that fits your medicine, budget and care needs.

MangoRx lists compounded medication only, and Sesame Care lists brand-name medication only. Sesame Care lists insurance support, and MangoRx does not.

Do MangoRx and Sesame Care offer brand-name medication?

MangoRx lists compounded medication only, and Sesame Care lists brand-name medication only.

Compounded medications are not FDA-approved. Your prescriber decides which medicine suits you.

Do MangoRx and Sesame Care take insurance?

Sesame Care lists insurance support, and MangoRx does not.

Confirm coverage for your exact plan and prescription before you pay.

Where these facts come from

MangoRx:prices checked October 10, 2026, score evidence assessed October 16, 2026.Read our MangoRx review

Sesame Care:prices checked October 9, 2026, score evidence assessed October 16, 2026.Read our Sesame Care review

We score on a published methodology, and partnership never changes a score or a fact here.

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