MangoRx vs Sesame Care: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher

Reviewed & updated August 14, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

54 providers verified independently·Independent research·How we rank →

Short answer: Sesame Care scores higher on our rubric, 7.9/10 against 7.5/10. Full reasoning, pricing and the cases where the other one wins are below.

Visit Sesame Care - our pick of these two →or find your match

Sesame Care beats MangoRx overall, scoring 7.9/10 vs 7.5/10. Published pricing is not a like-for-like monthly comparison: MangoRx is from $299/mo; Sesame Care is published $99/mo; total not verified. Choose MangoRx for needle-phobic users who want oral-only glp-1 tablets from a publicly traded company. Choose Sesame Care for users who want cheap fda-approved brand-name glp-1 access ($149-349/mo wegovy and zepbound via success by sesame), or insured patients who just need a prescriber.

A side-by-side look at MangoRx and Sesame Care to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

MangoRx

#22 of 54

7.5/10

Multi-service telehealth platform offering compounded GLP-1 alongside other health services.

Visit MangoRx

Higher Rated

Sesame Care

#5 of 54

7.9/10

Telehealth marketplace offering both a low-cost consultation model ($25/visit) and the new Success by Sesame membership program ($59/mo on 3/6/12-month plans), which coordinates access to FDA-approved brand-name GLP-1 medications including Foundayo (orforglipron), Wegovy pen and pill, and Zepbound. Medication is billed separately.

Visit Sesame Care

Feature	MangoRx	Sesame Care
Why each one	Oral dissolving tablets exclusively (zero injections) from a publicly traded company (NASDAQ: MGRX) with SEC-level financial transparency.	The broadest FDA-approved brand-name GLP-1 menu among low-cost telehealth options, Wegovy pen and pill, Zepbound, Ozempic, Mounjaro, Rybelsus, and Foundayo, coordinated through the new Success by Sesame membership at $59/mo plus medication.
Our Score	7.5/10	7.9/10
Headline Price	from $299/mo	published $99/mo; total not verified
Medication Type	Compounded	Both
Insurance Accepted	No	Yes
Best For	Needle-phobic users who want oral-only GLP-1 tablets from a publicly traded company	Users who want cheap FDA-approved brand-name GLP-1 access ($149-349/mo Wegovy and Zepbound via Success by Sesame), or insured patients who just need a prescriber
Watch out for	Oral semaglutide at $299/mo runs 2-3x injectable alternatives ($99-149/mo). The premium only makes sense if needles are a hard no for you.	Two distinct products (pay-per-visit vs the Success membership) sit side by side, so decide which you're buying before checkout
Ranking	#22	#5
Get started	Visit MangoRx	Visit Sesame Care

Pros & Cons Compared

MangoRx

Pros

+Oral dissolving tablets exclusively, zero injections for any GLP-1 option
+Publicly traded on NASDAQ (MGRX), SEC-required financial transparency that private competitors can't match
+Semaglutide tablet includes Vitamin B6 to help reduce nausea during treatment
+Free 100% online consultation with no video call required

Cons

−Oral semaglutide at $299/mo runs 2-3x injectable alternatives ($99-149/mo). The premium only makes sense if needles are a hard no for you.
−Early-stage public company with limited revenue; the same SEC filings that provide transparency also show the financial uncertainty reflected in the stock.
−Oral tablets are the only format, with no injectable option if you want higher bioavailability. If you may switch to injections later, pick a platform that carries both.

Sesame Care

Pros

+Success by Sesame program launched 2026, $59/mo on a 3/6/12-month plan, includes labs, unlimited messaging, and provider choice; medication is separate
+Brand-name cash pricing is competitive, Wegovy pen $199 intro / $349 ongoing, Zepbound vial $299, Wegovy pill $149
+Foundayo (Lilly's FDA-approved oral GLP-1) available as of April 2026 at $149/mo
+Original pay-per-visit model still available at $25/consultation for users who just need a prescriber

Cons

−Two distinct products (pay-per-visit vs the Success membership) sit side by side, so decide which you're buying before checkout
−The $59/mo Success by Sesame rate requires a 3-month minimum commitment; month-to-month is available at $99/mo if you don't want to commit
−Compounded meds are de-emphasized in the current marketing, the platform now leads with FDA-approved brand-name paths
−A marketplace rather than a concierge, expect less hand-holding than dedicated subscription platforms

Our Verdict

Sesame Care edges out MangoRx with a score of 7.9/10 vs 7.5/10. Published pricing is not a like-for-like monthly comparison: MangoRx is from $299/mo; Sesame Care is published $99/mo; total not verified. Sesame Care accepts insurance, which can significantly reduce your out-of-pocket costs. Sesame Care offers both brand-name and compounded medications, giving you more flexibility.