Comparison · updated October 24, 2026

MangoRx vs SkinnyRx: MangoRx for compounded medication only, SkinnyRx for brand-name or compounded options

MangoRx and SkinnyRx differ in what you pay and which medicines they list. Compounded medicines are not FDA-approved.

These two prices are different kinds of bill, so read the line under each price before you compare them.

Compare plans and terms

MangoRx and SkinnyRx pay us a commission when you join through our links. That never changes a score, an order or a fact on this page. How we make money

Which should you choose, MangoRx or SkinnyRx?

Short answer: Choose SkinnyRx if you want brand-name medicine as an option. If that doesn't matter to you, compare their plans below.

MangoRx is best for

Adults considering a compounded oral tablet who can confirm the full bill before choosing.

Choose SkinnyRx if

  • you want brand-name medicine as an option

The available assessments do not establish a score winner, so choose by the medicine, total cost and care you need.

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

MangoRx vs SkinnyRx side by side

MangoRx and SkinnyRx compared fact by fact
MangoRxSkinnyRx
Pricefrom $67Advertised monthly Slim rate; confirm refill interval and consultation fees$99First month, ask the renewal price
MedicineCompounded onlyBrand-name and compounded
Needle-free optionBothYes, a pill or other oral form
InsuranceBothNo insurance listed
ConsultationFree when the visit ends in a prescriptionIncluded
ShippingStandard UPS Ground shipping includedFree (overnight on all orders)
Where it ships46 states plus Washington D.C. The FAQ shipping list leaves out Alabama, Alaska, Arkansas and Mississippi, and there is no separate state list for the Slim weight loss tablet47 for compounded medications (its terms exclude Alabama, Louisiana and Mississippi and bar residents of those states from ordering them); branded offerings may be available in all states
Trustpilot4.4 / 5 across 18 reviews4.8 / 5 across 4,100 reviews
Our score2.4/10 Limited5/10 Mixed
Assessment limitsChecked Oct 16, 2026; few independent reviews yet.Checked Oct 16, 2026; a rating claim didn't match Trustpilot.

What MangoRx and SkinnyRx plans cost

MangoRx

Slim is a compounded oral dissolving semaglutide tablet with Vitamin B6, rather than an injection.

  • Slim oral semaglutide tablets$67Advertised from $67/month, billed monthly on the product page. The general subscription FAQ says auto-refills process every 25 days. Standard ground shipping is included; confirm the selected supply, first payment, refill schedule, any consultation fees and full bill.
How MangoRx bills

Slim advertises a starting $67/month and says billed monthly on its product page. The general Subscribe and Save FAQ says auto-refills process every 25 days. Confirm the selected Slim supply, first payment, refill schedule and full total; consultation charges can apply if treatment is unsuitable after the appointment.

We checked MangoRx's prices on October 24, 2026.

SkinnyRx

A four-product compounded menu with separate injection and dissolving-tablet pages for semaglutide and tirzepatide. Compare the exact formulation, introductory bill and renewal terms; the different routes are not established as clinically equivalent.

All 4 SkinnyRx plans
  • Compounded Tirzepatide (tablets)$199Oral dissolving tablet, quoted at $199 for the first month. Confirm the exact dispensing directions and later bill; this is not an FDA-approved oral tirzepatide product.
How SkinnyRx bills

$99 is a first month rate quoted on the compounded semaglutide and tirzepatide injection product pages. SkinnyRx does not publish a month two price; its terms say the renewal rate is described during checkout.

We checked SkinnyRx's prices on September 26, 2026.

What to watch for with MangoRx and SkinnyRx

MangoRx

  • Slim's product page says billed monthly, while the general subscription FAQ says auto-refills process every 25 days. Confirm the selected supply, renewal and fee terms before comparing complete bills.
  • Company-wide reviews are a small sample and do not establish results for the Slim tablet.
MangoRx's strengths, cautions and terms

Strengths

  • Oral dissolving tablets exclusively, zero injections for any GLP-1 option
  • Mangoceuticals, Inc. publishes corporate information; company disclosure is separate from clinical quality
  • Slim lists compounded semaglutide with Vitamin B6; an ingredient listing does not establish a nausea benefit
  • Intake is 100% online with no insurance needed, and the provider visit costs nothing when it ends in a prescription

More to watch for

  • The verified GLP-1 menu is oral-only. A compounded tablet is not interchangeable with an FDA-approved product, and injection results do not establish its effectiveness.
Medicines listed
  • Semaglutide 1 to 6 mg compounded with Vitamin B6 into a mint-flavored oral dissolving tablet, sold as Slim and the only weight loss product in the catalogue (verified 2026-09-03)
Insurance
No insurance support listed
Consultation
Free when the visit ends in a prescription. The refund policy charges $80 for a video consult or $70 for a phone consult if GLP-1s are judged not a good fit after the appointment, and $80 for a cancellation inside 24 hours or a no-show (verified 2026-09-03)
Shipping
Standard UPS Ground shipping included. Optional two-day and overnight shipping cost extra at the rates offered for the order.
States
46 states plus Washington D.C. The FAQ shipping list leaves out Alabama, Alaska, Arkansas and Mississippi, and there is no separate state list for the Slim weight loss tablet (verified 2026-09-03)
Cancellation
Published on the refund policy page: cancel or reschedule at least 24 hours ahead or pay an $80 fee, no-shows are also $80, refund requests must be made within 30 days, and the terms state all sales are final with auto-refills cancellable up to 48 hours before renewal (verified 2026-09-03)

SkinnyRx

  • Every advertised price is a first month rate and SkinnyRx does not publish what month two costs. Its terms say the renewal rate is described at checkout, and that discounts may be reversed if you cancel before the end of a promotional or committed term.
  • SkinnyRx names its medical director, Sajad Zalzala, M.D., and names AyaRx as the telemedicine partner behind its medical services, but it does not name the compounding pharmacy that fills prescriptions and it publishes no founders or executive team.
SkinnyRx's strengths, cautions and terms

Strengths

  • Four product-specific options to discuss with a clinician: semaglutide or tirzepatide, each as an injection or a dissolving tablet
  • $99 for the first month on both the compounded semaglutide and the compounded tirzepatide injection, quoted on each product page, among the lowest entry rates in the compounded segment
  • Fast onboarding: a short online intake, a prescription within 24 hours where no video visit is required, and free overnight shipping on all orders with tracking within 2 business days
  • A public Trustpilot profile provides service feedback to read alongside the FDA record and the written billing terms; those reviews do not establish tablet effectiveness

More to watch for

  • Cash-pay only, does not bill commercial insurance, Medicare, or Medicaid. HSA/FSA payments are accepted, which is the main way to soften the cost.
  • Independent reviews flag inconsistent customer-service responsiveness, a real consideration since titration support and dose adjustments run through chat
  • FDA warning letter #717989, issued February 20, 2026 to Lean Rx, Inc. dba SkinnyRx, cites misleading labels and website claims for compounded GLP-1s. It is a labeling/marketing record, not an unsafe-medication finding
Medicines listed
  • Semaglutide (compounded, injectable)
  • Wegovy Pill (brand-name oral semaglutide, badged FDA-approved on its product page but shown as Unavailable and offered via SkinnyRx Membership, no price published, verified 2026-09-03)
  • Foundayo Pill (brand-name orforglipron, badged FDA-approved on its product page but shown as Unavailable and offered via SkinnyRx Membership, no price published, verified 2026-09-03)
  • Semaglutide (compounded, oral dissolving tablets; confirm placement with the dispensing pharmacy)
  • Tirzepatide (compounded, injectable)
  • Tirzepatide (compounded, oral dissolving tablets; confirm placement with the dispensing pharmacy)
Insurance
No insurance support listed
Consultation
Included
Shipping
Free (overnight on all orders)
States
47 for compounded medications (its terms exclude Alabama, Louisiana and Mississippi and bar residents of those states from ordering them); branded offerings may be available in all states
Cancellation
The September 22 terms allow renewal processing up to five days before the next period and require cancellation at least five days before the applicable renewal-processing date. They include non-refundable fees, return-before-refund conditions and possible reversal of promotional discounts. Product FAQs use simpler cancellation/refund wording. Ask support for the exact deadline, refund eligibility and any return requirement in writing before paying; canceling is not a guaranteed refund.

Compounded medicines are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality before they are sold. Read the FDA's explanation of the risks.

MangoRx vs SkinnyRx: common questions

Is MangoRx or SkinnyRx cheaper?

At least one headline price is a starting, introductory, prepaid or partial figure, so neither is simply cheaper.

  • MangoRxfrom $67advertised monthly Slim rate; confirm refill interval and consultation fees
  • SkinnyRx$99first month, ask the renewal price

Which is better, MangoRx or SkinnyRx?

Neither wins outright on our scores, so the better one is the one that fits your medicine, budget and care needs.

MangoRx lists compounded medication only, and SkinnyRx lists brand-name and compounded medication.

Do MangoRx and SkinnyRx offer brand-name medication?

MangoRx lists compounded medication only, and SkinnyRx lists brand-name and compounded medication.

Compounded medications are not FDA-approved. Your prescriber decides which medicine suits you.

Do MangoRx and SkinnyRx take insurance?

Neither MangoRx nor SkinnyRx lists insurance support.

Where these facts come from

MangoRx:prices checked October 24, 2026, score evidence assessed October 16, 2026.Read our MangoRx review

SkinnyRx:prices checked September 26, 2026, score evidence assessed October 16, 2026.Read our SkinnyRx review

We score on a published methodology, and partnership never changes a score or a fact here.

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