MangoRx vs TrimRx: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

52 providers verified independently·Independent researchHow we rank →

TrimRx beats MangoRx overall, scoring 7.8/10 vs 7.5/10. TrimRx is more affordable at $149/mo vs $299/mo. Choose MangoRx for needle-phobic users who want oral-only glp-1 tablets from a . Choose TrimRx for users who want affordable compounded semaglutide at one flat.

A side-by-side look at MangoRx and TrimRx to help you decide. We compare them on:

  • Starting price per month
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for

MangoRx

#26 of 52
7.5/10

Multi-service telehealth platform offering compounded GLP-1 alongside other health services.

Visit MangoRx
Higher Rated

TrimRx

#11 of 52
7.8/10

Budget-friendly compounded GLP-1 provider with straightforward pricing and a focus on accessibility.

Visit TrimRx
FeatureMangoRxTrimRx
Our Score7.5/107.8/10
Starting Price$299/mo$149/mo
Medication TypeCompoundedCompounded
Insurance AcceptedNoNo
Best ForNeedle-phobic users who want oral-only GLP-1 tablets from a publicly traded companyUsers who want affordable compounded semaglutide at one flat, all-inclusive price
Ranking#26#11
Get startedVisit MangoRxVisit TrimRx

Pros & Cons Compared

MangoRx

Pros

  • +Oral dissolving tablets exclusively, zero injections for any GLP-1 option
  • +Publicly traded on NASDAQ (MGRX), SEC-required financial transparency that private competitors can't match
  • +Semaglutide tablet includes Vitamin B6 to help reduce nausea during treatment
  • +Free 100% online consultation with no video call required

Cons

  • Oral semaglutide at $299/mo runs 2-3x injectable alternatives ($99-149/mo). The premium only makes sense if needles are a hard no for you.
  • Early-stage public company with limited revenue; the same SEC filings that provide transparency also show the financial uncertainty reflected in the stock.
  • Oral tablets are the only format, with no injectable option if you want higher bioavailability. If you may switch to injections later, pick a platform that carries both.

TrimRx

Pros

  • +$149/mo all-inclusive for compounded semaglutide, one of the lowest prices for a full-service program
  • +Onboarding takes under 15 minutes with same-day provider review for most applications
  • +Free medication replacement if your shipment is lost or damaged in transit

Cons

  • Compounded semaglutide is the only medication, no tirzepatide and no brand-name options. Pick TrimRx only if you already know semaglutide is your drug.
  • No insurance billing and no superbill for out-of-network reimbursement, so treat the $149/mo as a pure cash-pay price

Our Verdict

TrimRx edges out MangoRx with a score of 7.8/10 vs 7.5/10. If budget is your priority, TrimRx starts at $149/mo compared to MangoRx's $299/mo. Choose MangoRx if you want: needle-phobic users who want oral-only glp-1 tablets from a publicly traded company. Choose TrimRx if you want: users who want affordable compounded semaglutide at one flat, all-inclusive price.

Still undecided? Editor's Featured Pick

Yucca Health

$146/mo · 7.7/10 · Compounded

If neither MangoRx nor TrimRx feels like the right fit, our featured pick across all 52 GLP-1 telehealth providers is Yucca Health. It is not the highest-scored provider in our full rankings. We feature it for its low-friction value: a flat $146/mo that stays the same at every dose.

Try MangoRx

Starting at $299/mo

Visit MangoRx

Try TrimRx

Starting at $149/mo

Visit TrimRx

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Featured Partners

Four affiliate partners we feature, we may earn a commission.

Yucca Health

7.7/10
$146/mo·Compounded

Gala

7.2/10
$149/mo·Brand & Compounded

TrimRx

7.8/10
$149/mo·Compounded

SkinnyRx

7.3/10
$199/mo·Compounded

Affiliate links, we earn a commission at no extra cost to you. These are featured partners, prioritized by our affiliate economics, not an editorial "best" ranking. The objective ranking (by methodology score) and full methodology are at glp1picks.com/best.