MEDVi vs SkinnyRx: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher

Reviewed & updated August 14, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

54 providers verified independently·Independent research·How we rank →

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MEDVi beats SkinnyRx overall, scoring 5.7/10 vs 5.3/10. Published pricing is not a like-for-like monthly comparison: MEDVi is $179 first month, then $299/mo; SkinnyRx is from $199/mo. Choose MEDVi for users who want both oral and injectable compounded options i. Choose SkinnyRx for users who want flexibility in compounded glp-1 medication fo.

A side-by-side look at MEDVi and SkinnyRx to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

Higher Rated

MEDVi

#46 of 54

5.7/10

MEDVi offers oral and injectable compounded GLP-1 care. Semaglutide is $179 for month one and $299 for refills. Trustpilot is 4.4/5 across roughly 11,000 reviews, while BBB is F/not accredited. FDA warning letter #721455 concerns misleading labeling and marketing, not an allegation that the medication was unsafe.

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SkinnyRx

#48 of 54

5.3/10

Direct-to-consumer telehealth platform offering compounded GLP-1 medications across five formats, injectable and sublingual semaglutide, semaglutide tablets, and tirzepatide as either injectable or tablets. Operated by Lean Rx, Inc. (Sacramento, CA). Compounded only, does not prescribe brand-name Wegovy/Zepbound/Ozempic/Mounjaro. Cash-pay only with HSA/FSA accepted; does not bill insurance. 4,100+ Trustpilot reviews at 4.8 stars.

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Feature	MEDVi	SkinnyRx
Why each one	Oral and injectable compounded formats in one program, with micro-dosing options and a path to FDA-approved brand medication.	The broadest compounded-GLP-1 menu in DTC telehealth, five medication formats including the uncommon sublingual semaglutide and even rarer oral tirzepatide tablets. Most competitors offer one or two formats; SkinnyRx covers every administration route a compounded patient might prefer.
Our Score	5.7/10	5.3/10
Headline Price	$179 first month, then $299/mo	from $199/mo
Medication Type	Both	Compounded
Insurance Accepted	No	No
Best For	Users who want both oral and injectable compounded options in one telehealth program	Users who want flexibility in compounded GLP-1 medication format (injectable, sublingual, or tablet) at a mid-tier price point
Watch out for	FDA warning letter #721455, issued February 20, 2026, cites misleading labeling and marketing that implied MEDVi compounded the drugs and that compounded products were equivalent to or FDA-evaluated like approved brands. The letter does not allege unsafe medication	No brand-name FDA-approved options (Wegovy, Zepbound, Ozempic, Mounjaro), so patients who want or need an FDA-approved finished product should buy elsewhere
Ranking	#46	#48
Get started	Visit MEDVi	Visit SkinnyRx

Pros & Cons Compared

MEDVi

Pros

+One of the few compounded providers offering both oral tablets and injectable semaglutide
+Micro-dosing options available, can start at sub-standard doses for patients concerned about side effects
+Sleek onboarding experience with clear progress tracking through their patient portal
+$179 covers the first month of compounded semaglutide on the current Katalys landing, including clinician review, medication and shipping

Cons

−FDA warning letter #721455, issued February 20, 2026, cites misleading labeling and marketing that implied MEDVi compounded the drugs and that compounded products were equivalent to or FDA-evaluated like approved brands. The letter does not allege unsafe medication
−Its third-party records conflict: 4.4/5 across roughly 11,000 Trustpilot reviews, but an F and no accreditation at the BBB
−The $179 semaglutide price is introductory; the current Katalys landing says refills are $299/mo, making the first-year total $3,468 rather than $2,148
−Brand-name Wegovy and Zepbound paths add a $99 membership plus the medication cost, which the current landing does not publish; availability can change
−No insurance accepted, and oral compounded semaglutide has less clinical data than injectable forms

SkinnyRx

Pros

+Five medication formats, the broadest compounded-GLP-1 menu in DTC telehealth, including the rare oral tirzepatide tablet that almost no competitor offers
+$199/mo entry price for both injectable and sublingual semaglutide is competitive in the mid-tier compounded segment
+Fast onboarding: 5-10 minute online questionnaire, physician review in 24-48 hours, medication delivered in 3-7 business days with temperature-controlled shipping
+4,100+ Trustpilot reviews at 4.8 stars, among the strongest aggregate social-proof signals in the GLP-1 telehealth category

Cons

−No brand-name FDA-approved options (Wegovy, Zepbound, Ozempic, Mounjaro), so patients who want or need an FDA-approved finished product should buy elsewhere
−Light public disclosure: founders, executive team, medical director, and specific compounding-pharmacy partners are not named on the public site, ask support before enrolling if provenance matters to you
−Cash-pay only, does not bill commercial insurance, Medicare, or Medicaid. HSA/FSA payments are accepted, which is the main way to soften the cost.
−Independent reviews flag inconsistent customer-service responsiveness, a real consideration since titration support and dose adjustments run through chat
−FDA warning letter #717989, issued February 20, 2026 to Lean Rx, Inc. dba SkinnyRx, cites misleading labels and website claims for compounded GLP-1s. It is a labeling/marketing record, not an unsafe-medication finding

Our Verdict

MEDVi edges out SkinnyRx with a score of 5.7/10 vs 5.3/10. Published pricing is not a like-for-like monthly comparison: MEDVi is $179 first month, then $299/mo; SkinnyRx is from $199/mo. MEDVi offers both brand-name and compounded medications, giving you more flexibility. Choose MEDVi if you want: users who want both oral and injectable compounded options in one telehealth program. Choose SkinnyRx if you want: users who want flexibility in compounded glp-1 medication format (injectable, sublingual, or tablet) at a mid-tier price point.