Strut Health vs TMates: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher

Reviewed & updated August 14, 2026 · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

54 providers verified independently·Independent research·How we rank →

Short answer: TMates scores higher on our rubric, 7.8/10 against 6.2/10. Full reasoning, pricing and the cases where the other one wins are below.

Visit TMates - our pick of these two →or find your match

TMates beats Strut Health overall, scoring 7.8/10 vs 6.2/10. Published pricing is not a like-for-like monthly comparison: Strut Health is from $99/mo; TMates is from $158/mo. Choose Strut Health for users who prefer a needle-free oral semaglutide option at a reasonable price. Choose TMates for users who want commitment-discount pricing on compounded glp-1s ($158-$249/mo, medication included) or a $99/mo clinical path to brand wegovy or zepbound filled at their own pharmacy.

A side-by-side look at Strut Health and TMates to help you decide. We compare them on:

•Starting price per month
•Our overall score, out of 10
•Medication type, brand-name or compounded
•Whether they accept insurance
•Who each one is best for

Strut Health

#43 of 54

6.2/10

Oral-focused GLP-1 provider offering needle-free semaglutide options for users who prefer pills over injections.

Visit Strut Health

Higher Rated

TMates

#11 of 54

7.8/10

Telemedicine platform offering two distinct archetypes: compounded semaglutide and tirzepatide with medication included (commitment pricing $158-$249/mo), and a clinical-service-only path to brand-name Wegovy/Zepbound at $99/mo where the prescription is sent to the patient's pharmacy. Phentermine also available. 2026 expansion added brand-name FDA-approved options.

Visit TMates

Feature	Strut Health	TMates
Why each one	Needle-free first: oral compounded semaglutide from $99/mo, one of the lowest oral entry prices anywhere, with oral tirzepatide and auto-refill injectables on the same platform if you switch.	Two-archetype platform: (1) compounded GLP-1s with medication included and steep multi-month commitment discounts; (2) cheap $99/mo clinical service for brand Wegovy/Zepbound where you fill the prescription at your own pharmacy.
Our Score	6.2/10	7.8/10
Headline Price	from $99/mo	from $158/mo
Medication Type	Compounded	Both
Insurance Accepted	No	Yes
Best For	Users who prefer a needle-free oral semaglutide option at a reasonable price	Users who want commitment-discount pricing on compounded GLP-1s ($158-$249/mo, medication included) or a $99/mo clinical path to brand Wegovy or Zepbound filled at their own pharmacy
Watch out for	Compounded only, no brand-name Wegovy or Zepbound. Strut does not publish formulation-specific pharmacokinetic or comparative outcome evidence for its oral tablets, so their absorption and weight-loss results versus approved injections are unknown.	The $99/mo Wegovy/Zepbound tier is the clinical service only. Medication is billed separately at your pharmacy (can be $1,000+/mo cash without insurance). Choose this tier when your insurance covers the drug itself.
Ranking	#43	#11
Get started	Visit Strut Health	Visit TMates

Pros & Cons Compared

Strut Health

Pros

+Specializes in oral compounded semaglutide, the go-to for patients who absolutely won't do injections
+Needle-free oral semaglutide tablets from $99/mo, one of the lowest oral entry prices in the table, with oral tirzepatide ($199/mo) and auto-refill injectables ($149 to $199/mo) if you switch formats
+Clear educational content about oral semaglutide absorption and how to maximize effectiveness
+Simple enrollment: online questionnaire, async provider review, medication shipped to your door

Cons

−Compounded only, no brand-name Wegovy or Zepbound. Strut does not publish formulation-specific pharmacokinetic or comparative outcome evidence for its oral tablets, so their absorption and weight-loss results versus approved injections are unknown.
−Compounded oral semaglutide is not FDA-approved as a finished product or established as bioequivalent to approved oral or injectable semaglutide; do not infer equivalent dosing or results

TMates

Pros

+Clinical-service-only path to brand Wegovy and Zepbound at $99/mo, prescription goes to patient's pharmacy (you fill separately using insurance or cash)
+Steep multi-month commitment discounts on compounded sema, $158/mo on 12-month plan ($1,900 upfront) vs $249/mo month-to-month
+Same price at all dose levels for compounded, no cost escalation as you titrate up
+Phentermine available at $149/mo for patients who benefit from a different appetite-suppressant approach

Cons

−The $99/mo Wegovy/Zepbound tier is the clinical service only. Medication is billed separately at your pharmacy (can be $1,000+/mo cash without insurance). Choose this tier when your insurance covers the drug itself.
−The best compounded rates require prepayment: $1,050 upfront for 6 months, $1,900 for 12. Start at $249 month-to-month if you want to test fit first.
−The intake is a 90-second quiz. Fast, but lighter screening than competitors with full medical intakes. Better suited to patients who already know GLP-1 basics.
−TMates prescribes brand-name but does not dispense it, and is not affiliated with Novo Nordisk (Wegovy) or Eli Lilly (Zepbound). Your own pharmacy fills the Rx.

Our Verdict

TMates edges out Strut Health with a score of 7.8/10 vs 6.2/10. Published pricing is not a like-for-like monthly comparison: Strut Health is from $99/mo; TMates is from $158/mo. TMates accepts insurance, which can significantly reduce your out-of-pocket costs. TMates offers both brand-name and compounded medications, giving you more flexibility.