MangoRx vs TMates: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

48 providers verified independently·Independent research·How we rank →

TMates beats MangoRx overall, scoring 7.8/10 vs 7.5/10. TMates is more affordable at $158/mo vs $299/mo. Choose MangoRx for users who want a multi-service telehealth platform covering . Choose TMates for users who want flexible pricing across compounded glp-1s (me.

A side-by-side comparison of MangoRx and TMates covering pricing, scores, medication types, insurance, and more to help you decide.

MangoRx

#27 of 48

7.5/10

Multi-service telehealth platform offering compounded GLP-1 alongside other health services.

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Higher Rated

TMates

#16 of 48

7.8/10

Telemedicine platform offering two distinct archetypes: compounded semaglutide and tirzepatide with medication included (commitment pricing $158-$249/mo), and a clinical-service-only path to brand-name Wegovy/Zepbound at $99/mo where the prescription is sent to the patient's pharmacy. Phentermine also available. 2026 expansion added brand-name FDA-approved options.

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Feature	MangoRx	TMates
Our Score	7.5/10	7.8/10
Starting Price	$299/mo	$158/mo
Medication Type	Compounded	Both
Insurance Accepted	No	Yes
Best For	Users who want a multi-service telehealth platform covering weight loss and men's health	Users who want flexible pricing across compounded GLP-1s (medication included, $158-$249/mo with commitment discounts) and a cheap clinical-service-only path to brand Wegovy or Zepbound ($99/mo, patient fills at own pharmacy)
Ranking	#27	#16

Pros & Cons Compared

MangoRx

Pros

+Oral dissolving tablets exclusively — zero injections for any GLP-1 option
+Publicly traded on NASDAQ (MGRX) — SEC-required financial transparency that private competitors can't match
+Semaglutide tablet includes Vitamin B6 to help reduce nausea during treatment
+Free 100% online consultation with no video call required

Cons

−$299/mo for oral semaglutide is 2-3x the cost of injectable alternatives at $99-149/mo
−Early-stage public company with limited revenue — stock performance reflects financial uncertainty
−Only oral tablet format available — no injectable options if you want higher bioavailability

TMates

Pros

+Steep multi-month commitment discounts on compounded sema — $158/mo on 12-month plan ($1,900 upfront) vs $249/mo month-to-month
+Clinical-service-only path to brand Wegovy and Zepbound at $99/mo — prescription goes to patient's pharmacy (you fill separately using insurance or cash)
+Same price at all dose levels for compounded — no cost escalation as you titrate up
+Phentermine available at $149/mo for patients who benefit from a different appetite-suppressant approach

Cons

−Brand Wegovy/Zepbound $99/mo is CLINICAL SERVICE ONLY — medication cost is separate (paid at your pharmacy, which can be $1,000+/mo cash without insurance)
−Best compounded pricing requires 6-12 month prepayment (upfront $1,050-$1,900)
−90-second assessment quiz suggests convenience over clinical thoroughness compared to competitors with full medical intakes
−Not affiliated with Novo Nordisk (Wegovy) or Eli Lilly (Zepbound) — TMates prescribes but does not dispense brand-name

Our Verdict

TMates edges out MangoRx with a score of 7.8/10 vs 7.5/10. If budget is your priority, TMates starts at $158/mo compared to MangoRx's $299/mo. TMates accepts insurance, which can significantly reduce your out-of-pocket costs. TMates offers both brand-name and compounded medications, giving you more flexibility. Choose MangoRx if you want: users who want a multi-service telehealth platform covering weight loss and men's health. Choose TMates if you want: users who want flexible pricing across compounded glp-1s (medication included, $158-$249/mo with commitment discounts) and a cheap clinical-service-only path to brand wegovy or zepbound ($99/mo, patient fills at own pharmacy).

Still undecided? Editor's #1 Overall Pick

Eden Health GLP-1

$249/mo · 8.9/10 · Both

If neither MangoRx nor TMates feels like the right fit, our overall #1 pick across all 48 GLP-1 telehealth providers is Eden Health GLP-1 — strongest balance of clinical oversight, transparent pricing, and verified availability.

Visit Eden Health GLP-1→Read our full Eden Health GLP-1 review