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AgelessRx vs Sesame Care: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice
54 providers verified independently·Independent researchHow we rank →

Short answer: Sesame Care scores higher on our rubric, 7.9/10 against 7.0/10. Full reasoning, pricing and the cases where the other one wins are below.

Sesame Care beats AgelessRx overall, scoring 7.9/10 vs 7/10. Published pricing is not a like-for-like monthly comparison: AgelessRx is from $199/mo + $50/mo clinical oversight; Sesame Care is published $99/mo; total not verified. Choose AgelessRx for longevity-minded users who want glp-1 alongside anti-aging treatments. Choose Sesame Care for users who want cheap fda-approved brand-name glp-1 access ($149-349/mo wegovy and zepbound via success by sesame), or insured patients who just need a prescriber.

A side-by-side look at AgelessRx and Sesame Care to help you decide. We compare them on:

  • Starting price per month
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for

AgelessRx

#40 of 54
7/10

Longevity-focused telehealth platform combining GLP-1 medications with anti-aging and wellness treatments.

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Higher Rated

Sesame Care

#5 of 54
7.9/10

Telehealth marketplace offering both a low-cost consultation model ($25/visit) and the new Success by Sesame membership program ($59/mo on 3/6/12-month plans), which coordinates access to FDA-approved brand-name GLP-1 medications including Foundayo (orforglipron), Wegovy pen and pill, and Zepbound. Medication is billed separately.

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FeatureAgelessRxSesame Care
Why each oneLongevity medicine pioneer offering GLP-1 microdosing alongside anti-aging treatments (NAD+, metformin, rapamycin), no membership fee required.The broadest FDA-approved brand-name GLP-1 menu among low-cost telehealth options, Wegovy pen and pill, Zepbound, Ozempic, Mounjaro, Rybelsus, and Foundayo, coordinated through the new Success by Sesame membership at $59/mo plus medication.
Our Score7/107.9/10
Headline Pricefrom $199/mo + $50/mo clinical oversightpublished $99/mo; total not verified
Medication TypeBothBoth
Insurance AcceptedNoYes
Best ForLongevity-minded users who want GLP-1 alongside anti-aging treatmentsUsers who want cheap FDA-approved brand-name GLP-1 access ($149-349/mo Wegovy and Zepbound via Success by Sesame), or insured patients who just need a prescriber
Watch out for$50/mo clinical oversight fee is charged on top of medication; the published $199 semaglutide path totals $249/moTwo distinct products (pay-per-visit vs the Success membership) sit side by side, so decide which you're buying before checkout
Ranking#40#5
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Pros & Cons Compared

AgelessRx

Pros

  • +No membership fee, pay only for treatments you choose, unlike platforms that require $50-149/mo subscriptions
  • +GLP-1 microdosing protocols available from $79/mo, one of only two platforms offering sub-therapeutic doses for metabolic health
  • +Broader longevity medicine platform with NAD+, metformin, and rapamycin alongside GLP-1 treatment
  • +Brand-name Zepbound available via LillyDirect partnership starting at $349/mo

Cons

  • $50/mo clinical oversight fee is charged on top of medication; the published $199 semaglutide path totals $249/mo
  • Longevity medicine framing may overwhelm patients who just want straightforward weight loss medication
  • Cold-shipping limitations may affect availability in Alaska and Hawaii

Sesame Care

Pros

  • +Success by Sesame program launched 2026, $59/mo on a 3/6/12-month plan, includes labs, unlimited messaging, and provider choice; medication is separate
  • +Brand-name cash pricing is competitive, Wegovy pen $199 intro / $349 ongoing, Zepbound vial $299, Wegovy pill $149
  • +Foundayo (Lilly's FDA-approved oral GLP-1) available as of April 2026 at $149/mo
  • +Original pay-per-visit model still available at $25/consultation for users who just need a prescriber

Cons

  • Two distinct products (pay-per-visit vs the Success membership) sit side by side, so decide which you're buying before checkout
  • The $59/mo Success by Sesame rate requires a 3-month minimum commitment; month-to-month is available at $99/mo if you don't want to commit
  • Compounded meds are de-emphasized in the current marketing, the platform now leads with FDA-approved brand-name paths
  • A marketplace rather than a concierge, expect less hand-holding than dedicated subscription platforms

Our Verdict

Sesame Care edges out AgelessRx with a score of 7.9/10 vs 7/10. Published pricing is not a like-for-like monthly comparison: AgelessRx is from $199/mo + $50/mo clinical oversight; Sesame Care is published $99/mo; total not verified. Sesame Care accepts insurance, which can significantly reduce your out-of-pocket costs.

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