AgelessRx vs Sesame Care: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

48 providers verified independently·Independent research·How we rank →

Sesame Care beats AgelessRx overall, scoring 7.9/10 vs 7/10. Sesame Care is more affordable at $99/mo vs $340/mo. Choose AgelessRx for longevity-minded users who want glp-1 alongside anti-aging t. Choose Sesame Care for users who want cheap fda-approved brand-name glp-1 access ($.

A side-by-side comparison of AgelessRx and Sesame Care covering pricing, scores, medication types, insurance, and more to help you decide.

AgelessRx

#47 of 48

7/10

Longevity-focused telehealth platform combining GLP-1 medications with anti-aging and wellness treatments.

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Higher Rated

Sesame Care

#10 of 48

7.9/10

Telehealth marketplace offering both a low-cost consultation model ($25/visit) and the new Success by Sesame membership program ($59/mo on 3/6/12-month plans) that bundles FDA-approved brand-name GLP-1 medications — including Foundayo (orforglipron), Wegovy pen and pill, and Zepbound.

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Feature	AgelessRx	Sesame Care
Our Score	7/10	7.9/10
Starting Price	$340/mo	$99/mo
Medication Type	Both	Both
Insurance Accepted	No	Yes
Best For	Longevity-minded users who want GLP-1 alongside anti-aging treatments	Users who want cheap FDA-approved brand-name GLP-1 access ($149-349/mo Wegovy and Zepbound via Success by Sesame), or insured patients who just need a prescriber
Ranking	#47	#10

Pros & Cons Compared

AgelessRx

Pros

+No membership fee — pay only for treatments you choose, unlike platforms that require $50-149/mo subscriptions
+GLP-1 microdosing protocols available from $79/mo — one of only two platforms offering sub-therapeutic doses for metabolic health
+Broader longevity medicine platform with NAD+, metformin, and rapamycin alongside GLP-1 treatment
+Brand-name Zepbound available via LillyDirect partnership starting at $349/mo

Cons

−$50/mo clinical oversight fee on top of medication cost — semaglutide totals ~$340/mo, making it one of the pricier options
−Longevity medicine framing may overwhelm patients who just want straightforward weight loss medication
−Cold-shipping limitations may affect availability in Alaska and Hawaii

Sesame Care

Pros

+Success by Sesame program launched 2026 — $59/mo on a 3/6/12-month plan, bundles labs, unlimited messaging, and provider choice
+Brand-name cash pricing is competitive — Wegovy pen $199 intro / $349 ongoing, Zepbound vial $299, Wegovy pill $149
+Foundayo (Lilly's FDA-approved oral GLP-1) available as of April 2026 at $149/mo
+Original pay-per-visit model still available at $25/consultation for users who just need a prescriber

Cons

−Membership model adds complexity — two distinct products (pay-per-visit vs Success membership) can be confusing
−Success by Sesame requires a 3-month minimum commitment to hit the $59/mo rate
−Compounded meds are de-emphasized on the current marketing — focus has shifted to FDA-approved brand-name paths
−Less hand-holding than dedicated subscription platforms like Willow or Eden Health

Our Verdict

Sesame Care edges out AgelessRx with a score of 7.9/10 vs 7/10. If budget is your priority, Sesame Care starts at $99/mo compared to AgelessRx's $340/mo. Sesame Care accepts insurance, which can significantly reduce your out-of-pocket costs. Choose AgelessRx if you want: longevity-minded users who want glp-1 alongside anti-aging treatments. Choose Sesame Care if you want: users who want cheap fda-approved brand-name glp-1 access ($149-349/mo wegovy and zepbound via success by sesame), or insured patients who just need a prescriber.

Still undecided? Editor's #1 Overall Pick

Eden Health GLP-1

$249/mo · 8.9/10 · Both

If neither AgelessRx nor Sesame Care feels like the right fit, our overall #1 pick across all 48 GLP-1 telehealth providers is Eden Health GLP-1 — strongest balance of clinical oversight, transparent pricing, and verified availability.

Visit Eden Health GLP-1→Read our full Eden Health GLP-1 review