Enhance MD vs Oak Longevity: Which GLP-1 Provider Is Better?
By Iacob Pastina, Independent Researcher
Enhance MD beats Oak Longevity overall, scoring 7.8/10 vs 7.5/10. Oak Longevity is more affordable at $130/mo vs $212/mo. Choose Enhance MD for budget-conscious users interested in combination therapies. Choose Oak Longevity for budget-conscious users who want one of the cheapest compound.
A side-by-side comparison of Enhance MD and Oak Longevity covering pricing, scores, medication types, insurance, and more to help you decide.
Enhance MD
#17 of 42Affordable telehealth provider offering both compounded and brand-name GLP-1 medications with combination therapy options.
Visit Enhance MDOak Longevity
#23 of 42Telehealth platform offering compounded semaglutide and tirzepatide at the lower end of market pricing, alongside an oral Wegovy option, brand-name FDA-approved GLP-1s, and a longevity stack (NAD+, Glutathione, Sermorelin, Tesamorelin). Distinctive non-subscription billing — patients pay each month manually rather than auto-renew.
Visit Oak Longevity| Feature | Enhance MD | Oak Longevity |
|---|---|---|
| Our Score | 7.8/10 | 7.5/10 |
| Starting Price | $212/mo | $130/mo |
| Medication Type | Both | Both |
| Insurance Accepted | No | No |
| Best For | Budget-conscious users interested in combination therapies | Budget-conscious users who want one of the cheapest compounded GLP-1 entries plus a no-subscription billing model and a longevity-stack add-on (NAD+, Sermorelin) |
| Ranking | #17 | #23 |
Pros & Cons Compared
Enhance MD
Pros
- +$115/mo starting price with access to both brand-name and compounded — rare at this price point
- +Offers combination therapies (GLP-1 + B12, GLP-1 + NAD+) for patients wanting enhanced protocols
- +Quick asynchronous consultations — most patients approved within 24 hours without video calls
- +Flexible dosing: can start at lower doses than standard protocols for sensitive patients
Cons
- −Lighter clinical support than higher-priced platforms — check-ins are patient-initiated, not scheduled
- −No insurance billing and limited customer support hours (business days only, no weekends)
Oak Longevity
Pros
- +$130/mo for compounded semaglutide is among the cheapest entries on the market — Sprout Health ($99) and Sesame Care ($99) are lower, but Oak undercuts most mid-tier platforms
- +Compounded tirzepatide at $199/mo is competitively priced for a GLP-1+GIP dual agonist
- +No-subscription model — patients are not auto-charged each month, choose to renew manually. Reduces unwanted recurring charges
- +Broadest medication mix on the platform: compounded sema + tirz, oral Wegovy, brand Wegovy/Ozempic/Zepbound/Mounjaro, plus longevity peptides (NAD+, Glutathione, Sermorelin, Tesamorelin)
- +Money-back guarantee if not approved by physician — useful safety net for borderline-eligibility patients
- +Free shipping and free health coaching included in every program
Cons
- −Brand-name pricing ($1,200-$1,500/mo) is significantly above market — NovoCare direct pricing for Wegovy is $349/mo, LillyDirect Zepbound $299/mo. Never buy brand-name through Oak
- −No published lab panels, no specialty (obesity medicine) physicians disclosed — clinical depth is shallow
- −'Up to 50% cheaper than competitors' marketing claim is unverified and inconsistent — depends on which competitor and which medication tier
- −'Longevity' framing pushes users toward add-on products (NAD+, Sermorelin, Tesamorelin) that have limited clinical evidence for weight loss specifically
- −Newer brand without disclosed company history, founding date, or executive team on landing pages
- −Three-month plans are billed upfront — pricing transparency is good, but commit-up-front is a friction point for users testing the platform
Our Verdict
Enhance MD edges out Oak Longevity with a score of 7.8/10 vs 7.5/10. If budget is your priority, Oak Longevity starts at $130/mo compared to Enhance MD's $212/mo. Choose Enhance MD if you want: budget-conscious users interested in combination therapies. Choose Oak Longevity if you want: budget-conscious users who want one of the cheapest compounded glp-1 entries plus a no-subscription billing model and a longevity-stack add-on (nad+, sermorelin).