Enhance MD vs Oak Longevity: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice
54 providers verified independently·Independent researchHow we rank →

Short answer: Enhance MD scores higher on our rubric, 7.8/10 against 7.5/10. Full reasoning, pricing and the cases where the other one wins are below.

Enhance MD beats Oak Longevity overall, scoring 7.8/10 vs 7.5/10. Published pricing is not a like-for-like monthly comparison: Enhance MD is from $212/mo; Oak Longevity is from $167/mo. Choose Enhance MD for cash-pay shoppers who want the monthly price to stay flat as the dose goes up, and who will do a lab draw and a video visit to get it. Choose Oak Longevity for budget-conscious users who want one of the cheapest compounded glp-1 entries, a flat price across every dose, and a longevity-stack add-on (nad+, glutathione, sermorelin).

A side-by-side look at Enhance MD and Oak Longevity to help you decide. We compare them on:

  • Starting price per month
  • Our overall score, out of 10
  • Medication type, brand-name or compounded
  • Whether they accept insurance
  • Who each one is best for
Higher Rated

Enhance MD

#12 of 54
7.8/10

Cash-pay telehealth program selling compounded semaglutide, compounded tirzepatide, a formulation containing both, and a low-dose microdosing tirzepatide plan. Every GLP-1 it sells is compounded and not FDA-approved; there is no brand-name option. The price is flat at every dose, $212/mo on the 12-month plan and $249/mo month to month (verified 2026-09-03).

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Oak Longevity

#18 of 54
7.5/10

Telehealth platform offering compounded semaglutide and tirzepatide at the lower end of market pricing, across injectable and non-injectable routes, alongside a longevity stack (NAD+, Glutathione, Sermorelin). Every dose is priced the same, so titrating up does not raise the monthly cost. Plans run as a subscription that renews automatically and can be cancelled from the account at any time.

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FeatureEnhance MDOak Longevity
Why each oneThe most affordable platform offering both medication types plus unique combination therapies (GLP-1 + B12, GLP-1 + NAD+) that no other major provider offers at this price.
One price per medication regardless of dose, so titrating up does not raise the bill. Combined with three compounded routes and a longevity peptide menu, Oak reads as a 'menu' platform rather than the typical single-product flow.
Our Score7.8/107.5/10
Headline Pricefrom $212/mofrom $167/mo
Medication TypeCompoundedCompounded
Insurance AcceptedNoNo
Best ForCash-pay shoppers who want the monthly price to stay flat as the dose goes up, and who will do a lab draw and a video visit to get it
Budget-conscious users who want one of the cheapest compounded GLP-1 entries, a flat price across every dose, and a longevity-stack add-on (NAD+, Glutathione, Sermorelin)
Watch out forThe $212/mo headline is the 12-month plan, billed every 48 weeks. Paying month to month costs $249/mo on the GLP-1 Core pricing page (verified 2026-09-03)
Compounded is all you can actually buy. Its employer page says brand name is available alongside compounded tirzepatide and semaglutide, but no consumer page sells a brand product and the site has no Wegovy, Zepbound, Ozempic or Mounjaro page (rendered check 2026-09-03)
Ranking#12#18
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Pros & Cons Compared

Enhance MD

Pros

  • +Same price at every dose, so titrating up does not raise the monthly bill. GLP-1 Core is $212/mo on the 12-month plan and $249/mo month to month (verified 2026-09-03)
  • +The monthly price covers lab work, the video visit with a provider, medication from a partner pharmacy and 2-day shipping, with no separate consultation fee
  • +Support is staffed seven days a week, Monday to Friday 8:00 AM to 8:00 PM EDT and Saturday to Sunday 9:00 AM to 5:00 PM EDT, by phone and email
  • +Four compounded GLP-1 options including a capped 1mg microdosing tirzepatide plan at $169/mo, plus a full refund of the initial payment if a provider finds you ineligible during onboarding

Cons

  • The $212/mo headline is the 12-month plan, billed every 48 weeks. Paying month to month costs $249/mo on the GLP-1 Core pricing page (verified 2026-09-03)
  • Compounded only. Every GLP-1 product page states the formulation is not FDA-approved and is compounded under federal Section 503A guidelines, and no brand-name product is sold
  • Not nationwide. The FAQ lists 40 states plus DC and leaves out Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina and Tennessee
  • Cash pay with no same-day start: a Quest Diagnostics blood draw and a scheduled video visit both come before a prescription, and no insurance option is shown on the site's pricing, FAQ or terms pages (rendered check 2026-09-03)

Oak Longevity

Pros

  • +A $167/mo starting price on its compounded semaglutide page, with no membership fee, free shipping and free health coaching included
  • +Every dose costs the same, so moving to a higher dose during titration does not raise the monthly bill, stated on the product page and in the blog
  • +Three compounded routes including a non-injectable oral or sublingual option, unusual at this price
  • +Longevity peptides (NAD+, Glutathione, Sermorelin) sit alongside the GLP-1 menu on one platform
  • +Money-back guarantee if not approved by physician, useful safety net for borderline-eligibility patients
  • +Free shipping and free health coaching included in every program

Cons

  • Compounded is all you can actually buy. Its employer page says brand name is available alongside compounded tirzepatide and semaglutide, but no consumer page sells a brand product and the site has no Wegovy, Zepbound, Ozempic or Mounjaro page (rendered check 2026-09-03)
  • Obesity-certified doctors are advertised on the weight loss page, but no clinician roster or credentials are published, and no lab panels or blood work are offered anywhere on the site (rendered check 2026-09-03)
  • The 'up to 50% cheaper than competitors' marketing claim is unverified and inconsistent, judge Oak on its posted prices, which are genuinely low, not on the slogan
  • The longevity add-ons it lists (NAD+, Glutathione, Sermorelin) have limited clinical evidence for weight loss specifically, if weight loss is the goal, the GLP-1 alone does the work and the stack is optional
  • The operating entity appears only in the footer and legal pages, as Leaf Longevity Holdings Corp trading as Oak Longevity, and no founding date, named leadership, about page or team page exists on the site (rendered check 2026-09-03)
  • Its published starting price is not consistent: $119 a month in the homepage FAQ, $167 on the compounded semaglutide page, $180 in its own blog and $190 on the weight loss page, so settle the figure at checkout before you commit

Our Verdict

Enhance MD edges out Oak Longevity with a score of 7.8/10 vs 7.5/10. Published pricing is not a like-for-like monthly comparison: Enhance MD is from $212/mo; Oak Longevity is from $167/mo.

Cheapest complete recurring price in our index

Eden Health GLP-1

$99/mo month-to-month, from $34 on a plan · 6.9/10 · Both

Both Enhance MD and Oak Longevity start above the cheapest complete recurring program we track. Across all 54 providers in our index, the lowest price with affirmative medication, consultation, and shipping inclusion is Eden Health GLP-1 at $99/mo, price checked August 28, 2026. It scores 6.9/10 and is not the highest-scored provider in our full rankings, so this is a cost floor rather than a recommendation. Worth knowing before you decide.

Try Enhance MD

Headline price: from $212/mo

Visit Enhance MD

Try Oak Longevity

Headline price: from $167/mo

Visit Oak Longevity

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