Comparison · updated October 25, 2026

Sesame Care vs SkinnyRx: Sesame Care for brand-name medication only, SkinnyRx for brand-name or compounded options

Sesame Care and SkinnyRx differ in what you pay, which medicines they list and their insurance terms. Compounded medicines are not FDA-approved.

These two prices are different kinds of bill, so read the line under each price before you compare them.

Compare plans and terms

Sesame Care and SkinnyRx pay us a commission when you join through our links. That never changes a score, an order or a fact on this page. How we make money

Which should you choose, Sesame Care or SkinnyRx?

Short answer: Choose Sesame Care if you want to use insurance. Choose SkinnyRx if you want a compounded option as well as brand-name medicine.

Choose Sesame Care if

  • you want to use insurance

Choose SkinnyRx if

  • you want a compounded option as well as brand-name medicine

The available assessments do not establish a score winner, so choose by the medicine, total cost and care you need.

By Iacob Pastina, Independent Researcher & Publisher
Reviewed & updated · Cites primary sources (FDA, NEJM, CMS) · Not medical advice

Sesame Care vs SkinnyRx side by side

Sesame Care and SkinnyRx compared fact by fact
Sesame CareSkinnyRx
Price$99/moProgram fee + medication; confirm monthly vs 28-day billing$99First month, ask the renewal price
MedicineBrand-name onlyBrand-name and compounded
Needle-free optionBothYes, a pill or other oral form
InsuranceAccepts insuranceNo insurance listed
ConsultationVisits start at $34 on the homepage, with some services listed from $36; visits are included in the Success by Sesame subscriptionIncluded
ShippingNot publishedFree (overnight on all orders)
Where it shipsNot confirmed: we could not verify which states Sesame Care serves47 for compounded medications (its terms exclude Alabama, Louisiana and Mississippi and bar residents of those states from ordering them); branded offerings may be available in all states
Trustpilot4.6 / 5 across 4,533 reviews4.8 / 5 across 4,100 reviews
BBB ratingA+Not tracked
Our score6.7/10 Fair5/10 Mixed
Assessment limitsBothChecked Oct 16, 2026; a rating claim didn't match Trustpilot.

What Sesame Care and SkinnyRx plans cost

Sesame Care

Provider choice, ongoing video care and medication prior-authorization help, with a separately priced brand-name GLP-1 menu and $59/mo advertised care on an annual commitment.

  • Success by Sesame (12-month plan)$59The $59/mo headline rate. The program page footnote reads "Based on a 12-month Success by Sesame commitment". Bundles provider visits, unlimited messaging and provider choice. Medication is separate.
  • Success by Sesame (6-month plan)$69Billed once every 6 months. The FAQ publishes this as a saving of $180 every 6 months against the $99 monthly rate, which works out near $69/mo. Medication is separate.
  • Success by Sesame (3-month plan)$79Billed once every 3 months. The FAQ publishes this as a saving of $60 every 3 months against the $99 monthly rate, which works out near $79/mo. Medication is separate.
All 9 Sesame Care plans
  • Success by Sesame (month-to-month)$99$99 program fee with no commitment; medication is separate. One program FAQ says billed every month, while another says every 28 days. Confirm the billing interval, your next payment date and how many charges you will pay in a year.
  • Single Consultation (pay-per-visit)$34One-off telehealth visit, no subscription required. The homepage says visits start at $34 and lists some services from $36.
  • Wegovy Pen (brand-name cash)$199Medication only: $199/month for the first two consecutive months at 0.25 or 0.5 mg for eligible new self-pay patients through December 31, 2026, then $349 for listed 0.25–2.4 mg doses. Care fees are separate
  • Wegovy Pill (oral semaglutide)$149Sesame lists $149/mo at 1.5 or 4 mg and $299 at 9 or 25 mg. Medication only; confirm current offer eligibility and add the separate care fee
  • Zepbound KwikPen (brand-name cash)$299The detailed menu lists $299 at 2.5 mg, $398 at 5 mg, $499 at 7.5 mg and $698 at 10–15 mg. A separate vial teaser also says from $299. Confirm the prescribed format and applicable manufacturer offer; care fees are separate
  • Foundayo (orforglipron oral)$149Medication only. Through December 31, 2026, Sesame's offer FAQ lists $149 at 0.8/2.5 mg, $199 at 5.5 mg and $299 at 9 mg. At 14.5/17.2 mg it lists $349, or $299 with Journey Program terms and refills within 45 days. The medication card shows higher non-promotional figures at some doses; confirm the applicable offer and add care fees
How Sesame Care bills

Program fee only. Medication is extra, so confirm the full bill. The program page says monthly in one FAQ and every 28 days in another. Confirm the billing interval and combined bill before paying.

We checked Sesame Care's prices on October 9, 2026.

SkinnyRx

A four-product compounded menu with separate injection and dissolving-tablet pages for semaglutide and tirzepatide. Compare the exact formulation, introductory bill and renewal terms; the different routes are not established as clinically equivalent.

All 4 SkinnyRx plans
  • Compounded Tirzepatide (tablets)$199Oral dissolving tablet, quoted at $199 for the first month. Confirm the exact dispensing directions and later bill; this is not an FDA-approved oral tirzepatide product.
How SkinnyRx bills

$99 is a first month rate quoted on the compounded semaglutide and tirzepatide injection product pages. SkinnyRx does not publish a month two price; its terms say the renewal rate is described during checkout.

We checked SkinnyRx's prices on September 26, 2026.

What to watch for with Sesame Care and SkinnyRx

Sesame Care

  • Sesame runs three separate routes under one brand: the Success by Sesame weight loss subscription, EverydayRx for diabetes, and one-off visits from $34. Check which one you are signing up for before you pay.
  • The $59/mo Success by Sesame rate applies only on a 12-month commitment. The 3-month plan works out near $79/mo and the 6-month near $69/mo from the savings the FAQ publishes. For the $99 no-commitment plan, one FAQ says monthly and another says every 28 days. Confirm the interval and number of charges before budgeting for a year.
Sesame Care's strengths, cautions and terms

Strengths

  • Success by Sesame is $59/mo on the 12-month commitment and includes provider visits, unlimited messaging and provider choice; lab work is covered only at Quest Diagnostics and not in AZ, HI, ND, NJ, NY, OK, RI, SD or WY, where lab fees are extra; medication is separate
  • Published medication-only offers include eligible Wegovy pen starter doses at $199 for two months, then $349; the Wegovy pill and Zepbound KwikPen have dose-specific prices
  • Listed oral brands include Wegovy and Foundayo, with medication starting at $149 for eligible doses; the care fee is separate
  • Provider choice, ongoing video visits, messaging and app tools for weight, dose and side-effect tracking are described in the program

More to watch for

  • Sesame says compounded semaglutide is not currently available. Its published GLP-1 menu is brand-name; medication is billed on top of the program or visit fee.
  • Providers can set higher fees than the advertised program rate. Confirm the selected clinician's price and support arrangements before enrolling
Medicines listed
  • Wegovy (brand-name injection pen)
  • Wegovy (brand-name oral pill)
  • Ozempic (brand-name injection)
  • Zepbound (brand-name KwikPen/vial)
  • Mounjaro (brand-name injection)
  • Rybelsus (brand-name oral)
  • Foundayo (brand-name orforglipron oral, FDA-approved April 2026)
Insurance
Lists insurance support. Confirm coverage for your plan.
Consultation
Visits start at $34 on the homepage, with some services listed from $36; visits are included in the Success by Sesame subscription (verified 2026-09-03)
Shipping
Not published. A shipping cost is not shown on the site's weight loss program, medication or FAQ pages (rendered check 2026-09-03). Prescriptions are picked up at a local pharmacy or sent by home delivery, so any delivery charge comes from the pharmacy
States
Not confirmed: we could not verify which states Sesame Care serves. Confirm your state during sign-up.
Cancellation
You can self-cancel Success by Sesame at any time, and cancellation must happen before the next billing cycle starts to avoid the next charge. A full refund applies only if you cancel at least 3 hours before the initial visit, no refund is issued for the first month once that visit has happened, and fees for previous months are not refundable (verified 2026-09-03)

SkinnyRx

  • Every advertised price is a first month rate and SkinnyRx does not publish what month two costs. Its terms say the renewal rate is described at checkout, and that discounts may be reversed if you cancel before the end of a promotional or committed term.
  • SkinnyRx names its medical director, Sajad Zalzala, M.D., and names AyaRx as the telemedicine partner behind its medical services, but it does not name the compounding pharmacy that fills prescriptions and it publishes no founders or executive team.
SkinnyRx's strengths, cautions and terms

Strengths

  • Four product-specific options to discuss with a clinician: semaglutide or tirzepatide, each as an injection or a dissolving tablet
  • $99 for the first month on both the compounded semaglutide and the compounded tirzepatide injection, quoted on each product page, among the lowest entry rates in the compounded segment
  • Fast onboarding: a short online intake, a prescription within 24 hours where no video visit is required, and free overnight shipping on all orders with tracking within 2 business days
  • A public Trustpilot profile provides service feedback to read alongside the FDA record and the written billing terms; those reviews do not establish tablet effectiveness

More to watch for

  • Cash-pay only, does not bill commercial insurance, Medicare, or Medicaid. HSA/FSA payments are accepted, which is the main way to soften the cost.
  • Independent reviews flag inconsistent customer-service responsiveness, a real consideration since titration support and dose adjustments run through chat
  • FDA warning letter #717989, issued February 20, 2026 to Lean Rx, Inc. dba SkinnyRx, cites misleading labels and website claims for compounded GLP-1s. It is a labeling/marketing record, not an unsafe-medication finding
Medicines listed
  • Semaglutide (compounded, injectable)
  • Wegovy Pill (brand-name oral semaglutide, badged FDA-approved on its product page but shown as Unavailable and offered via SkinnyRx Membership, no price published, verified 2026-09-03)
  • Foundayo Pill (brand-name orforglipron, badged FDA-approved on its product page but shown as Unavailable and offered via SkinnyRx Membership, no price published, verified 2026-09-03)
  • Semaglutide (compounded, oral dissolving tablets; confirm placement with the dispensing pharmacy)
  • Tirzepatide (compounded, injectable)
  • Tirzepatide (compounded, oral dissolving tablets; confirm placement with the dispensing pharmacy)
Insurance
No insurance support listed
Consultation
Included
Shipping
Free (overnight on all orders)
States
47 for compounded medications (its terms exclude Alabama, Louisiana and Mississippi and bar residents of those states from ordering them); branded offerings may be available in all states
Cancellation
The September 22 terms allow renewal processing up to five days before the next period and require cancellation at least five days before the applicable renewal-processing date. They include non-refundable fees, return-before-refund conditions and possible reversal of promotional discounts. Product FAQs use simpler cancellation/refund wording. Ask support for the exact deadline, refund eligibility and any return requirement in writing before paying; canceling is not a guaranteed refund.

Compounded medicines are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality before they are sold. Read the FDA's explanation of the risks.

Sesame Care vs SkinnyRx: common questions

Is Sesame Care or SkinnyRx cheaper?

At least one headline price is a starting, introductory, prepaid or partial figure, so neither is simply cheaper.

  • Sesame Care$99/moprogram fee + medication; confirm monthly vs 28-day billing
  • SkinnyRx$99first month, ask the renewal price

Which is better, Sesame Care or SkinnyRx?

Neither wins outright on our scores, so the better one is the one that fits your medicine, budget and care needs.

Sesame Care lists brand-name medication only, and SkinnyRx lists brand-name and compounded medication. Sesame Care lists insurance support, and SkinnyRx does not.

Do Sesame Care and SkinnyRx offer brand-name medication?

Sesame Care lists brand-name medication only, and SkinnyRx lists brand-name and compounded medication.

Compounded medications are not FDA-approved. Your prescriber decides which medicine suits you.

Do Sesame Care and SkinnyRx take insurance?

Sesame Care lists insurance support, and SkinnyRx does not.

Confirm coverage for your exact plan and prescription before you pay.

Where these facts come from

Sesame Care:prices checked October 9, 2026, score evidence assessed October 16, 2026.Read our Sesame Care review

SkinnyRx:prices checked September 26, 2026, score evidence assessed October 16, 2026.Read our SkinnyRx review

We score on a published methodology, and partnership never changes a score or a fact here.

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