Sesame Care vs SkinnyRx: Which GLP-1 Provider Is Better?
By Iacob Pastina, Independent Researcher
Sesame Care beats SkinnyRx overall, scoring 7.9/10 vs 7.3/10. Sesame Care is more affordable at $99/mo vs $199/mo. Choose Sesame Care for users who want cheap fda-approved brand-name glp-1 access ($. Choose SkinnyRx for users who want flexibility in compounded glp-1 medication fo.
A side-by-side look at Sesame Care and SkinnyRx to help you decide. We compare them on:
- •Starting price per month
- •Our overall score, out of 10
- •Medication type, brand-name or compounded
- •Whether they accept insurance
- •Who each one is best for
Sesame Care
#7 of 53Telehealth marketplace offering both a low-cost consultation model ($25/visit) and the new Success by Sesame membership program ($59/mo on 3/6/12-month plans) that bundles FDA-approved brand-name GLP-1 medications, including Foundayo (orforglipron), Wegovy pen and pill, and Zepbound.
Visit Sesame CareSkinnyRx
#35 of 53Direct-to-consumer telehealth platform offering compounded GLP-1 medications across five formats, injectable and sublingual semaglutide, semaglutide tablets, and tirzepatide as either injectable or tablets. Operated by Lean Rx, Inc. (Sacramento, CA). Compounded only, does not prescribe brand-name Wegovy/Zepbound/Ozempic/Mounjaro. Cash-pay only with HSA/FSA accepted; does not bill insurance. 4,100+ Trustpilot reviews at 4.8 stars.
Visit SkinnyRx| Feature | Sesame Care | SkinnyRx |
|---|---|---|
| Our Score | 7.9/10 | 7.3/10 |
| Starting Price | $99/mo | $199/mo |
| Medication Type | Both | Compounded |
| Insurance Accepted | Yes | No |
| Best For | Users who want cheap FDA-approved brand-name GLP-1 access ($149-349/mo Wegovy and Zepbound via Success by Sesame), or insured patients who just need a prescriber | Users who want flexibility in compounded GLP-1 medication format (injectable, sublingual, or tablet) at a mid-tier price point |
| Watch out for | Two distinct products (pay-per-visit vs the Success membership) sit side by side, so decide which you're buying before checkout | No brand-name FDA-approved options (Wegovy, Zepbound, Ozempic, Mounjaro), so patients who want or need an FDA-approved finished product should buy elsewhere |
| Ranking | #7 | #35 |
| Get started | Visit Sesame Care | Visit SkinnyRx |
Pros & Cons Compared
Sesame Care
Pros
- +Success by Sesame program launched 2026, $59/mo on a 3/6/12-month plan, bundles labs, unlimited messaging, and provider choice
- +Brand-name cash pricing is competitive, Wegovy pen $199 intro / $349 ongoing, Zepbound vial $299, Wegovy pill $149
- +Foundayo (Lilly's FDA-approved oral GLP-1) available as of April 2026 at $149/mo
- +Original pay-per-visit model still available at $25/consultation for users who just need a prescriber
Cons
- −Two distinct products (pay-per-visit vs the Success membership) sit side by side, so decide which you're buying before checkout
- −The $59/mo Success by Sesame rate requires a 3-month minimum commitment; month-to-month is available at $99/mo if you don't want to commit
- −Compounded meds are de-emphasized in the current marketing, the platform now leads with FDA-approved brand-name paths
- −A marketplace rather than a concierge, expect less hand-holding than dedicated subscription platforms
SkinnyRx
Pros
- +Five medication formats, the broadest compounded-GLP-1 menu in DTC telehealth, including the rare oral tirzepatide tablet that almost no competitor offers
- +$199/mo entry price for both injectable and sublingual semaglutide is competitive in the mid-tier compounded segment
- +Fast onboarding: 5-10 minute online questionnaire, physician review in 24-48 hours, medication delivered in 3-7 business days with temperature-controlled shipping
- +4,100+ Trustpilot reviews at 4.8 stars, among the strongest aggregate social-proof signals in the GLP-1 telehealth category
Cons
- −No brand-name FDA-approved options (Wegovy, Zepbound, Ozempic, Mounjaro), so patients who want or need an FDA-approved finished product should buy elsewhere
- −Light public disclosure: founders, executive team, medical director, and specific compounding-pharmacy partners are not named on the public site, ask support before enrolling if provenance matters to you
- −Cash-pay only, does not bill commercial insurance, Medicare, or Medicaid. HSA/FSA payments are accepted, which is the main way to soften the cost.
- −Independent reviews flag inconsistent customer-service responsiveness, a real consideration since titration support and dose adjustments run through chat
Our Verdict
Sesame Care edges out SkinnyRx with a score of 7.9/10 vs 7.3/10. If budget is your priority, Sesame Care starts at $99/mo compared to SkinnyRx's $199/mo. Sesame Care accepts insurance, which can significantly reduce your out-of-pocket costs. Sesame Care offers both brand-name and compounded medications, giving you more flexibility. Choose Sesame Care if you want: users who want cheap fda-approved brand-name glp-1 access ($149-349/mo wegovy and zepbound via success by sesame), or insured patients who just need a prescriber. Choose SkinnyRx if you want: users who want flexibility in compounded glp-1 medication format (injectable, sublingual, or tablet) at a mid-tier price point.
Read Full Reviews
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