Sesame Care vs SkinnyRx: Which GLP-1 Provider Is Better?
By Iacob Pastina, Independent Researcher
Sesame Care beats SkinnyRx overall, scoring 7.9/10 vs 7.3/10. Sesame Care is more affordable at $59/mo vs $199/mo. Choose Sesame Care for users who want cheap fda-approved brand-name glp-1 access ($. Choose SkinnyRx for users who want flexibility in compounded glp-1 medication fo.
A side-by-side comparison of Sesame Care and SkinnyRx covering pricing, scores, medication types, insurance, and more to help you decide.
Sesame Care
#10 of 47Telehealth marketplace offering both a low-cost consultation model ($25/visit) and the new Success by Sesame membership program ($59/mo on 3/6/12-month plans) that bundles FDA-approved brand-name GLP-1 medications — including Foundayo (orforglipron), Wegovy pen and pill, and Zepbound.
Visit Sesame CareSkinnyRx
#36 of 47Direct-to-consumer telehealth platform offering compounded GLP-1 medications across five formats — injectable and sublingual semaglutide, semaglutide tablets, and tirzepatide as either injectable or tablets. Operated by Lean Rx, Inc. (Sacramento, CA). Compounded only — does not prescribe brand-name Wegovy/Zepbound/Ozempic/Mounjaro. Cash-pay only with HSA/FSA accepted; does not bill insurance. 4,100+ Trustpilot reviews at 4.8 stars.
Visit SkinnyRx| Feature | Sesame Care | SkinnyRx |
|---|---|---|
| Our Score | 7.9/10 | 7.3/10 |
| Starting Price | $59/mo | $199/mo |
| Medication Type | Both | Compounded |
| Insurance Accepted | Yes | No |
| Best For | Users who want cheap FDA-approved brand-name GLP-1 access ($149-349/mo Wegovy and Zepbound via Success by Sesame), or insured patients who just need a prescriber | Users who want flexibility in compounded GLP-1 medication format (injectable, sublingual, or tablet) at a mid-tier price point |
| Ranking | #10 | #36 |
Pros & Cons Compared
Sesame Care
Pros
- +Success by Sesame program launched 2026 — $59/mo on a 3/6/12-month plan, bundles labs, unlimited messaging, and provider choice
- +Brand-name cash pricing is competitive — Wegovy pen $199 intro / $349 ongoing, Zepbound vial $299, Wegovy pill $149
- +Foundayo (Lilly's FDA-approved oral GLP-1) available as of April 2026 at $149/mo
- +Original pay-per-visit model still available at $25/consultation for users who just need a prescriber
Cons
- −Membership model adds complexity — two distinct products (pay-per-visit vs Success membership) can be confusing
- −Success by Sesame requires a 3-month minimum commitment to hit the $59/mo rate
- −Compounded meds are de-emphasized on the current marketing — focus has shifted to FDA-approved brand-name paths
- −Less hand-holding than dedicated subscription platforms like Willow or Eden Health
SkinnyRx
Pros
- +Five medication formats — the broadest compounded-GLP-1 menu in DTC telehealth, including the rare oral tirzepatide tablet that almost no competitor offers
- +$199/mo entry price for both injectable and sublingual semaglutide is competitive in the mid-tier compounded segment
- +Fast onboarding: 5–10 minute online questionnaire, physician review in 24–48 hours, medication delivered in 3–7 business days with temperature-controlled shipping
- +4,100+ Trustpilot reviews at 4.8 stars — among the strongest aggregate social-proof signals in the GLP-1 telehealth category
Cons
- −No brand-name FDA-approved options (Wegovy, Zepbound, Ozempic, Mounjaro) — compounded-only model limits patients who want or need an FDA-approved finished product
- −Limited public transparency: founders, executive team, medical director, and specific compounding-pharmacy partners are not named on the public site
- −Cash-pay only — does not bill commercial insurance, Medicare, or Medicaid (HSA/FSA payments accepted)
- −Independent reviews flag inconsistent customer-service responsiveness, which is a real concern for a medication that requires titration support and dose-adjustment dialogue
Our Verdict
Sesame Care edges out SkinnyRx with a score of 7.9/10 vs 7.3/10. If budget is your priority, Sesame Care starts at $59/mo compared to SkinnyRx's $199/mo. Sesame Care accepts insurance, which can significantly reduce your out-of-pocket costs. Sesame Care offers both brand-name and compounded medications, giving you more flexibility. Choose Sesame Care if you want: users who want cheap fda-approved brand-name glp-1 access ($149-349/mo wegovy and zepbound via success by sesame), or insured patients who just need a prescriber. Choose SkinnyRx if you want: users who want flexibility in compounded glp-1 medication format (injectable, sublingual, or tablet) at a mid-tier price point.